Osteoporosis PostmenopausalNCT07148479
Telerehabilitation Versus Traditional Balance Training in Women With Osteoporosis.
A study testing Telerehabilitation group and Traditional balance training group in people with Osteoporosis Postmenopausal, run by Riphah International University at 1 site in Pakistan.
Trial summary
Osteoporosis is a silent disease that leads to fractures, postural deformities, and impaired balance, especially in postmenopausal women. In Pakistan, prevalence is high, with 39% of women reported as severely osteoporotic. Read more about this study
- Who is it for?
- Ages 50 to 70 years, women only
- Conditions the study is for
- Osteoporosis Postmenopausal
- What is being tested?
- Telerehabilitation group and Traditional balance training group
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 0 participants
- Where
- 1 sitePakistan
- Study dates
- Jan 2026to Jul 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 70 years
- Women only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- • Women diagnosed with osteopenia and osteoporosis at hip and lumbar spine through DEXA
- Age 50-70 years
- Have mobile phones and can communicate in video call
- Have Balance score (21-44) on berg balance scale
- A caregiver must be available to assist the participant during Tele sessions.
Who cannot join
- • Women with severe mobility impairments.
- Women with cognitive conditions affecting participation.
- Women with lower limb joint injury or surgery
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of Telerehabilitation and Traditional Balance Training in Post Menopausal Women With Osteoporosis.
Osteoporosis is a silent disease that leads to fractures, postural deformities, and impaired balance, especially in postmenopausal women. In Pakistan, prevalence is high, with 39% of women reported as severely osteoporotic. Postmenopausal women with osteoporosis and balance issues face increased fall risk due to poor bone density, weakened muscles especially in the lower limb band altered posture .Balance and strength training reduce fall risk, but access to in-person rehabilitation is limited. Telerehabilitation provides remote delivery of structured exercise programs and has shown positive outcomes in balance and bone health. Few studies, however, have compared telerehabilitation with conventional training across all balance domains. The goal of this randomized controlled trial is to compare the effect of Telerehabilitation and Traditional Balance Training in Post Menopausal Women with osteoporosis. Participants will be randomly assigned to one of the two groups, and both will receive an identical standardized balance training program . The results of this clinical trial will help evaluate how telerehabilitation can improve the balance of postmenopausal women with osteoporosis and improve health outcomes.
Read the detailed description
Osteoporosis often remains undetected until fractures occur, typically involving the hip, wrist, or spine, and may also cause back pain, height loss, and kyphosis. Postmenopausal women face increased fall risk due to reduced bone density, weakened lower limb muscles, and altered posture. Many also develop fear of falling, which restricts activity and accelerates muscle weakness.
Globally, osteoporosis affects about 23.1% of women and 11.7% of men, with fragility fractures being a major cause of disability. In Pakistan, hospital-based findings show a high proportion of postmenopausal women as severely osteoporotic, with a strong link to fall-related injuries.
Exercise interventions, including balance, resistance, and weight-bearing training, are known to improve bone strength, postural control, and confidence by stimulating bone remodelling and enhancing musculoskeletal performance. Telerehabilitation, delivered via video conferencing, provides remote access to such programs and has demonstrated improvements in stability, weight-shifting, and functional balance.
However, most studies assess limited outcomes using tools like TUG or BBS, without addressing static, dynamic, anticipatory, and reactive balance together. Evidence largely comes from high-income countries, while data from resource-limited settings like Pakistan remain scarce. This trial seeks to evaluate telerehabilitation compared to traditional training across comprehensive balance domains in postmenopausal women with osteoporosis.
- Conditions
- Osteoporosis Postmenopausal
- Being tested
- Telerehabilitation group, Traditional balance training group
- Keywords
- Telerehabilitation, Balance, Osteoporosis, Posmenopausal, Virtual exercise
- Medical subject headings
- Osteoporosis, Postmenopausal, Osteoporosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Telerehabilitation groupOther
The telerehabilitation group participated in balance training sessions delivered through secure virtual platforms such as WhatsApp video calls. Participants completed 3 sessions per week, each lasting 45-60 minutes, over a total of 6 weeks (18 sessions). The program target static, dynamic, anticipatory, and reactive balance. participants will use households items.session began with warm-up exercises such as gentle marching, arm circles, and hamstring stretches, followed by balance training targeting static, dynamic, anticipatory, and reactive components. Exercises included heel-to-toe standing, single-leg stance, tandem stance, obstacle walking, heel-to-toe walking, side stepping, functional reach, weight shifting, caregiver-assisted perturbations, and foam surface standing. All exercises were performed in 3 sets with specified holds or repetitions. Sessions concluded with cool-down activities including tricep stretches, forward bends, and deep breathing.
Traditional balance training groupOther
Same as telerehabilitation group but it will concluded in a clinical setting.
| Study group | Role | What they receive |
|---|---|---|
| Telerehabilitation group | Experimental | This group will receive a 6 week structured telerehabilitation exercise protocol of low to moderate intensity (18 sessions , 3 sessions per week,45 to 60 minutes ), warmup, balance training and cool down exercises. delivered online by a physiotherapist and progressively increasing every three weeks. Receives: Other: Telerehabilitation group |
| Traditional Balance Training group | Active comparator | In the traditional balance training group the protocol will be delivered by a physiotherapist in a clinical environment face to face. The standardized balance training protocol will be monitored exactly the same as telerehabilitation group Receives: Other: Traditional balance training group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Berg Balance Scale score
The Berg Balance Scale (BBS) is a widely used clinical tool to assess static and dynamic balance in individuals, particularly older adults. It's a 14-item test that evaluates a person's ability to perform various balance-related tasks, such as sitting, standing, reaching, and turning. Each item is scored on a 0-4 scale, with 0 indicating the lowest level of function and 4 indicating the highest. The total score ranges from 0 to 56, with lower scores suggesting a higher risk of falls
Measured: Baseline and 6 weeks
Secondary outcomes (4)
Change in Time up and Go test score
The Timed Up and Go Test (TUG) is a simple yet widely validated tool used to assess mobility and fall risk. It measures how quickly an individual can rise from a chair, walk three meters, turn, walk back, and sit down
Measured: Baseline and 6 weeks
Functional reach test
The Functional Reach Test (FRT) assesses how far an individual can reach forward while standing, without stepping or losing balance. It's particularly effective for identifying balance limitations in frail or elderly populations
Measured: Baseline and 6 weeks
Change in Push and release test score
Push and Release Test is designed to measure reactive postural control by observing how a person recovers after being released from a supported backward lean.
Measured: Baseline and 6 weeks
Change in Single leg stance test score
The Single Leg Stance Test (SLS) is a simple but powerful tool to evaluate balance and stability, particularly in older adults or individuals with conditions like osteoporosis. In this test, the person is asked to stand on one leg usually with eyes open and hands on hips while the clinician times how long they can maintain that position without support. It's an effective way to spot balance problems that could lead to falls
Measured: Baseline and 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Aug 2025
- Study startJan 2026 (estimated)
- Primary completionJun 2026 (estimated)
- Study completionJul 2026 (estimated)
Why it stopped: Unavailability of patients and other resources to the researchers
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Osteoporosis PostmenopausalStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- There will be comparison between the two groups, experimental and control.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 0 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Prof. Dr. Huma Riaz, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07148479
- Sponsor's protocol ID
- Mehak bibi
- Status last verified
- Aug 2026
- First submitted
- 24 Aug 2025
- Last updated
- 27 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Li S, Li Y, Liang Q, Yang WJ, Zi R, Wu X, Du C, Jiang Y. Effects of tele-exercise rehabilitation intervention on women at high risk of osteoporotic fractures: study protocol for a randomised controlled trial. BMJ Open. 2022 Nov 7;12(11):e064328. doi: 10.1136/bmjopen-2022-064328.
PubMed 36344002Rezaei MK, Torkaman G, Bahrami F, Bayat N. The effect of six week virtual reality training on the improvement of functional balance in women with type-I osteoporosis: A preliminary study. Sport Sci Health. 2023;19(1):185-194. doi: 10.1007/s11332-022-01018-8. Epub 2022 Nov 15.
PubMed 36408530Wei F, Hu Z, He R, Wang Y. Effects of balance training on balance and fall efficacy in patients with Osteoporosis: A systematic review and meta-analysis with trial sequential analysis. J Rehabil Med. 2023 May 17;55:jrm00390. doi: 10.2340/jrm.v55.4529.
PubMed 37194565
Study at a glance
From the registry record, last updated by the sponsor on 27 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Telerehabilitation and Traditional Balance Training in Post Menopausal Women With Osteoporosis.
- ClinicalTrials.gov ID
- NCT07148479
- Acronym / sponsor ID
- Mehak bibi
- Conditions
- Osteoporosis Postmenopausal
- Keywords
- Telerehabilitation, Balance, Osteoporosis, Posmenopausal, Virtual exercise
- Study type
- Interventional
- Recruitment status
- WithdrawnReason stopped: Unavailability of patients and other resources to the researchers
- Enrolment
- 0 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- Jan 2026 (estimated)
- Primary completion
- Jun 2026 (estimated)
- Study completion
- Jul 2026 (estimated)
- First posted
- 29 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Osteoporosis is a silent disease that leads to fractures, postural deformities, and impaired balance, especially in postmenopausal women. In Pakistan, prevalence is high, with 39% of women reported as severely osteoporotic. Postmenopausal women with osteoporosis and balance issues face increased fall risk due to poor bone density, weakened muscles especially in the lower limb band altered posture .Balance and strength training reduce fall risk, but access to in-person rehabilitation is limited. Telerehabilitation provides remote delivery of structured exercise programs and has shown positive outcomes in balance and bone health. Few studies, however, have compared telerehabilitation with conventional training across all balance domains. The goal of this randomized controlled trial is to compare the effect of Telerehabilitation and Traditional Balance Training in Post Menopausal Women with osteoporosis. Participants will be randomly assigned to one of the two groups, and both will receive an identical standardized balance training program . The results of this clinical trial will help evaluate how telerehabilitation can improve the balance of postmenopausal women with osteoporosis and improve health outcomes.
Detailed description
Osteoporosis often remains undetected until fractures occur, typically involving the hip, wrist, or spine, and may also cause back pain, height loss, and kyphosis. Postmenopausal women face increased fall risk due to reduced bone density, weakened lower limb muscles, and altered posture. Many also develop fear of falling, which restricts activity and accelerates muscle weakness.
Globally, osteoporosis affects about 23.1% of women and 11.7% of men, with fragility fractures being a major cause of disability. In Pakistan, hospital-based findings show a high proportion of postmenopausal women as severely osteoporotic, with a strong link to fall-related injuries.
Exercise interventions, including balance, resistance, and weight-bearing training, are known to improve bone strength, postural control, and confidence by stimulating bone remodelling and enhancing musculoskeletal performance. Telerehabilitation, delivered via video conferencing, provides remote access to such programs and has demonstrated improvements in stability, weight-shifting, and functional balance.
However, most studies assess limited outcomes using tools like TUG or BBS, without addressing static, dynamic, anticipatory, and reactive balance together. Evidence largely comes from high-income countries, while data from resource-limited settings like Pakistan remain scarce. This trial seeks to evaluate telerehabilitation compared to traditional training across comprehensive balance domains in postmenopausal women with osteoporosis.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- There will be comparison between the two groups, experimental and control.
| Arm | Type | Receives |
|---|---|---|
| Telerehabilitation group | Experimental | Other: Telerehabilitation groupThis group will receive a 6 week structured telerehabilitation exercise protocol of low to moderate intensity (18 sessions , 3 sessions per week,45 to 60 minutes ), warmup, balance training and cool down exercises. delivered online by a physiotherapist and progressively increasing every three weeks. |
| Traditional Balance Training group | Active comparator | Other: Traditional balance training groupIn the traditional balance training group the protocol will be delivered by a physiotherapist in a clinical environment face to face. The standardized balance training protocol will be monitored exactly the same as telerehabilitation group |
Who may qualify
- Ages
- 50 to 70 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- • Women diagnosed with osteopenia and osteoporosis at hip and lumbar spine through DEXA
Key exclusion criteria (3 listed)
- • Women with severe mobility impairments.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Telerehabilitation groupThe telerehabilitation group participated in balance training sessions delivered through secure virtual platforms such as WhatsApp video calls. Participants completed 3 sessions per week, each lasting 45-60 minutes, over a total of 6 weeks (18 sessions). The program target static, dynamic, anticipatory, and reactive balance. participants will use households items.session began with warm-up exercises such as gentle marching, arm circles, and hamstring stretches, followed by balance training targeting static, dynamic, anticipatory, and reactive components. Exercises included heel-to-toe standing, single-leg stance, tandem stance, obstacle walking, heel-to-toe walking, side stepping, functional reach, weight shifting, caregiver-assisted perturbations, and foam surface standing. All exercises were performed in 3 sets with specified holds or repetitions. Sessions concluded with cool-down activities including tricep stretches, forward bends, and deep breathing. | Other | Telerehabilitation group |
| Traditional balance training groupSame as telerehabilitation group but it will concluded in a clinical setting. | Other | Traditional Balance Training group |
Primary outcome
Change in Berg Balance Scale score
Time frame: Baseline and 6 weeks
The Berg Balance Scale (BBS) is a widely used clinical tool to assess static and dynamic balance in individuals, particularly older adults. It's a 14-item test that evaluates a person's ability to perform various balance-related tasks, such as sitting, standing, reaching, and turning. Each item is scored on a 0-4 scale, with 0 indicating the lowest level of function and 4 indicating the highest. The total score ranges from 0 to 56, with lower scores suggesting a higher risk of falls
4 secondary outcomes
Change in Time up and Go test score
Time frame: Baseline and 6 weeks
Functional reach test
Time frame: Baseline and 6 weeks
Change in Push and release test score
Time frame: Baseline and 6 weeks
Change in Single leg stance test score
Time frame: Baseline and 6 weeks
Results and safety
The study was withdrawn before enrolling participants, so there are no results.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Aug 2026.
- Background: PubMed 36344002Li S, Li Y, Liang Q, Yang WJ, Zi R, Wu X, Du C, Jiang Y. Effects of tele-exercise rehabilitation intervention on women at high risk of osteoporotic fractures: study protocol for a randomised controlled trial. BMJ Open. 2022 Nov 7;12(11):e064328. doi: 10.1136/bmjopen-2022-064328.
- Background: PubMed 36408530Rezaei MK, Torkaman G, Bahrami F, Bayat N. The effect of six week virtual reality training on the improvement of functional balance in women with type-I osteoporosis: A preliminary study. Sport Sci Health. 2023;19(1):185-194. doi: 10.1007/s11332-022-01018-8. Epub 2022 Nov 15.
- Background: PubMed 37194565Wei F, Hu Z, He R, Wang Y. Effects of balance training on balance and fall efficacy in patients with Osteoporosis: A systematic review and meta-analysis with trial sequential analysis. J Rehabil Med. 2023 May 17;55:jrm00390. doi: 10.2340/jrm.v55.4529.
- Individual participant dataSharing planned: No
Related trials for Osteoporosis Postmenopausal
Active, not recruitingObservational study
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Prof. Dr. Huma Riaz principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Telerehabilitation group and Traditional balance training group in people with Osteoporosis Postmenopausal, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: withdrawn, as of the sponsor's last update on 27 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was withdrawn before enrolling participants, so there are no results.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Berg Balance Scale score (time frame: Baseline and 6 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07148479, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Aug 2026.