HiccupNCT07149025
OMT & Intractable Singultus
A study testing Osteopathic Manipulative Therapy in people with Hiccup, run by Michigan State University at 1 site in United States.
Trial summary
This study plans to use the effects osteopathic manipulative medicine (OMM) techniques to aid in treatment of patients with symptoms of, somatic dysfunction related to, and/or a diagnosis of Intractable Singultus. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Hiccup
- What is being tested?
- Osteopathic Manipulative Therapy
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 5 participants
- Where
- 1 siteUnited States
- Study dates
- 1 May 2023to 28 Feb 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Over 18 years old
- Living with daily episodes of hiccups that have lasted longer than 1 month
Who cannot join
- Any contraindications to OMT based on screening questionnaire or during treatment.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Intractable Singultus Pilot Study
This study plans to use the effects osteopathic manipulative medicine (OMM) techniques to aid in treatment of patients with symptoms of, somatic dysfunction related to, and/or a diagnosis of Intractable Singultus. The aim of our study is to document any changes in associated symptoms of Intractable Singultus before and after osteopathic manipulative treatment (OMT).
- Conditions
- Hiccup
- Being tested
- Osteopathic Manipulative Therapy
- Keywords
- intractable singultus, chronic hiccup
- Medical subject headings
- Hiccup
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Osteopathic Manipulative TherapyProcedure or surgery
Also called ONMM, OMM
1 session of OMT
| Study group | Role | What they receive |
|---|---|---|
| OMT | Experimental | Not described Receives: Procedure: Osteopathic Manipulative Therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of Hiccups
Measured: Days 1-7 before OMT (baseline), and Days 1-7 following OMT
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Aug 2025
- Study start1 May 2023
- Primary completion11 Feb 2025
- Study completion28 Feb 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HiccupStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 5 participants (actual)
Sponsor and investigators
- Lead sponsor
- Michigan State University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, J'Aimee Lippert, Michigan State University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07149025
- Sponsor's protocol ID
- STUDY 7900
- Status last verified
- Aug 2025
- First submitted
- 20 Aug 2025
- Last updated
- 29 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Intractable Singultus Pilot Study
- ClinicalTrials.gov ID
- NCT07149025
- Acronym / sponsor ID
- STUDY 7900
- Conditions
- Hiccup
- Keywords
- intractable singultus, chronic hiccup
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 5 participants (actual)
- Lead sponsor
- Michigan State UniversityUniversity, hospital or other
- Study start
- 1 May 2023 (actual)
- Primary completion
- 11 Feb 2025 (actual)
- Study completion
- 28 Feb 2025 (actual)
- First posted
- 29 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study plans to use the effects osteopathic manipulative medicine (OMM) techniques to aid in treatment of patients with symptoms of, somatic dysfunction related to, and/or a diagnosis of Intractable Singultus. The aim of our study is to document any changes in associated symptoms of Intractable Singultus before and after osteopathic manipulative treatment (OMT).
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| OMT | Experimental | Procedure: Osteopathic Manipulative Therapy |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Over 18 years old
- Living with daily episodes of hiccups that have lasted longer than 1 month
Key exclusion criteria (1 listed)
- Any contraindications to OMT based on screening questionnaire or during treatment.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Osteopathic Manipulative TherapyAlso: ONMM, OMM1 session of OMT | Procedure or surgery | OMT |
Primary outcome
Number of Hiccups
Time frame: Days 1-7 before OMT (baseline), and Days 1-7 following OMT
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Aug 2025.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Osteopathic Manipulative Therapy in people with Hiccup, run by Michigan State University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of Hiccups (time frame: Days 1-7 before OMT (baseline), and Days 1-7 following OMT). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Aug 2025; AzTrials last refreshed its copy on 1 Nov 2026.