Multiple SclerosisNCT07151534
Body Awareness, Trunk Stability, and Arm Function in MS
An observational study of Multiple Sclerosis, run by Hacettepe University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to investigate the relationship between body awareness, trunk stabilization, and upper extremity functionality in patients with Multiple Sclerosis (MS). Hypotheses of the study: H1: There is a significant relationship between body awareness and upper extremity functionality in patients with… Read more about this study
- Who is it for?
- Ages 10 years and olderHealthy volunteers can take part
- Conditions the study is for
- Multiple Sclerosis
- How many people
- 50 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 6 Aug 2025to 1 Jan 2027
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 years and older
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: MS patients and healthy subjects with inclusion criteria
Who may be able to join
- Diagnosed with Multiple Sclerosis (MS) by a neurologist according to the McDonald criteria
- Aged 18 years or older
- Expanded Disability Status Scale (EDSS) score ≤ 5
- Mini-Mental State Examination (MMSE) score ≥ 24
- A control group consisting of healthy individuals matched with MS patients in terms of age and sex
Who cannot join
- Having a neurological disorder other than MS
- Having experienced a relapse and/or used corticosteroids in the past 3 months
- Having an orthopedic/systemic condition affecting the upper extremities or trunk
- Being pregnant
- Refusing to participate or not providing written informed consent
- Healthy individuals who have an orthopedic/systemic condition affecting the upper extremities or trunk, who are pregnant, or who do not agree to participate and provide written informed consent will be excluded.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Hacettepe University
Ankara, Altındağ
Güngör Beyza Özvar Şenöz, PhD, 5053888617 ext. +90, beyzaozvar@gmail.com
About this study
Official title: Investigation of the Relationship Between Body Awareness, Trunk Stabilization, and Upper Extremity Functionality in Individuals With Multiple Sclerosis
The aim of this study is to investigate the relationship between body awareness, trunk stabilization, and upper extremity functionality in patients with Multiple Sclerosis (MS).
Hypotheses of the study:
H1: There is a significant relationship between body awareness and upper extremity functionality in patients with MS.
H2: There is a significant relationship between body awareness and trunk stabilization in patients with MS.
H3: Body awareness is reduced in patients with MS compared to healthy individuals.
H4: Trunk stabilization is reduced in patients with MS compared to healthy individuals.
H5: Upper extremity functionality is reduced in patients with MS compared to healthy individuals.
Read the detailed description
Patients' demographic and disease-specific information will be recorded. Subsequently, body awareness, upper extremity functionality, and trunk stabilization will be assessed.
- Conditions
- Multiple Sclerosis
- Keywords
- body awareness, upper extremity, trunk stabilization, multiple sclerosis
- Medical subject headings
- Multiple Sclerosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Multiple Sclerosis | Diagnosed with Multiple Sclerosis (MS) by a neurologist according to the McDonald criteria, aged 18 years or older, Expanded Disability Status Scale (EDSS) score of ≤ 5, Mini-Mental State Examination score of 24 or higher will be included in the study. | |
| Healthy | A control group consisting of healthy individuals matched with MS patients by age and sex will be included in the study. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Body Awareness Questionnaire
To assess body awareness, the Body Awareness Questionnaire will be used.This questionnaire consists of 18 items, each scored on a scale from 1 to 7, and evaluates body awareness. Higher scores indicate better body awareness. The Turkish version has been validated and found to be reliable.
Measured: up to 6 months
Body Awareness Rating Questionnaire
To assess body awareness,the Body Awareness Rating Questionnaire will be used. Body Awareness Rating Questionnaire:This questionnaire includes 24 items across 4 domains: function, mood, feeling/sensation, and awareness. Higher scores indicate better body awareness. The Turkish version has been validated and shown to be reliable.
Measured: up to 6 months
Upper Extremity Functionality-Grip strength
Grip strength will be measured with a Jamar dynamometer. It will be performed three times bilaterally, and average values (kg) will be recorded.
Measured: up to 6 months
Upper Extremity Functionality-Pinch strength
Pinch strengths will be assessed using a Baseline pinch gauge. It will be performed three times bilaterally, and average values (kg) will be recorded.
Measured: up to 6 months
Upper Extremity Functionality-Nine Hole Peg Test (9HPT)
The 9HPT will evaluate hand dexterity by timing how quickly participants place and remove nine pegs. Each hand will be tested three times. It will be recorded in seconds. An average time ≥33.3 seconds will indicate dysfunction in MS patients.
Measured: up to 6 months
Trunk Stabilization- Trunk Impairment Scale (TIS),
Trunk stabilization will be evaluated using the TIS.TIS: Assesses static/dynamic balance and trunk coordination (17 items, 0-23 points).
Measured: up to 6 months
Trunk Stabilization-plank endurance test
Trunk stabilization will be evaluated using the plank endurance test. The test measures core endurance. Plank test: Time held in forearm plank recorded. It will be recorded in seconds.
Measured: up to 6 months
Trunk Stabilization-side bridge test
Trunk stabilization will be evaluated using the side bridge test. The test measures core endurance Time held in side plank on both sides recorded.It will be recorded in seconds.
Measured: up to 6 months
Trunk Stabilization-Modified Biering-Sorensen
Trunk stabilization will be evaluated using the Modified Biering-Sorensen test. The test measures core endurance. Time holding trunk in horizontal position prone over table edge. It will be recorded in seconds.
Measured: up to 6 months
Trunk Stabilization-Trunk flexor test
Trunk stabilization will be evaluated using the Trunk flexor test test.The test measures core endurance. Time maintaining 60° trunk flexion with knees/hips at 90°. It will be recorded in seconds.
Measured: up to 6 months
Trunk Stabilization-Sit up test
The 30-second Sit-up Test measures core strength. The person lies on their back with knees bent and feet on the floor. They do as many sit-ups as possible in 30 seconds, keeping proper form. The score is the number of correct sit-ups completed.
Measured: up to 6 months
Trunk Stabilization-Modifiye push up test
The 30-second Modified Push-up Test measures core strength. The person starts in a push-up position but with knees on the floor. They perform as many push-ups as possible in 30 seconds, keeping the body straight and lowering the chest close to the ground. The score is the number of correct push-ups completed.
Measured: up to 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Sep 2025
- Study start6 Aug 2025
- Primary completion31 Dec 2026 (estimated)
- Study completion1 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Multiple SclerosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 50 participants (estimated)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Hacettepe University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Güngör Beyza ÖZVAR, Hacettepe University
- Investigators
- Muhammed Kılınç, Principal investigator, Hacettepe UniversityÖzge Onursal Kılınç, Study director, Hacettepe University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07151534
- Sponsor's protocol ID
- Body Awareness
- Status last verified
- Sep 2026
- First submitted
- 6 Aug 2025
- Last updated
- 17 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Relationship Between Body Awareness, Trunk Stabilization, and Upper Extremity Functionality in Individuals With Multiple Sclerosis
- ClinicalTrials.gov ID
- NCT07151534
- Acronym / sponsor ID
- Body Awareness
- Conditions
- Multiple Sclerosis
- Keywords
- body awareness, upper extremity, trunk stabilization, multiple sclerosis
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Hacettepe UniversityUniversity, hospital or other
- Study start
- 6 Aug 2025 (actual)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 1 Jan 2027 (estimated)
- First posted
- 3 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate the relationship between body awareness, trunk stabilization, and upper extremity functionality in patients with Multiple Sclerosis (MS).
Hypotheses of the study:
H1: There is a significant relationship between body awareness and upper extremity functionality in patients with MS.
H2: There is a significant relationship between body awareness and trunk stabilization in patients with MS.
H3: Body awareness is reduced in patients with MS compared to healthy individuals.
H4: Trunk stabilization is reduced in patients with MS compared to healthy individuals.
H5: Upper extremity functionality is reduced in patients with MS compared to healthy individuals.
Detailed description
Patients' demographic and disease-specific information will be recorded. Subsequently, body awareness, upper extremity functionality, and trunk stabilization will be assessed.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Target follow-up
- 1 Day
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Multiple Sclerosis | – | –Diagnosed with Multiple Sclerosis (MS) by a neurologist according to the McDonald criteria, aged 18 years or older, Expanded Disability Status Scale (EDSS) score of ≤ 5, Mini-Mental State Examination score of 24 or higher will be included in the study. |
| Healthy | – | –A control group consisting of healthy individuals matched with MS patients by age and sex will be included in the study. |
Who may qualify
- Ages
- 10 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- MS patients and healthy subjects with inclusion criteria
Key inclusion criteria (5 listed)
- Diagnosed with Multiple Sclerosis (MS) by a neurologist according to the McDonald criteria
- Aged 18 years or older
- Expanded Disability Status Scale (EDSS) score ≤ 5
- Mini-Mental State Examination (MMSE) score ≥ 24
Key exclusion criteria (6 listed)
- Having a neurological disorder other than MS
- Having experienced a relapse and/or used corticosteroids in the past 3 months
- Having an orthopedic/systemic condition affecting the upper extremities or trunk
- Being pregnant
- Refusing to participate or not providing written informed consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Body Awareness Questionnaire
Time frame: up to 6 months
To assess body awareness, the Body Awareness Questionnaire will be used.This questionnaire consists of 18 items, each scored on a scale from 1 to 7, and evaluates body awareness. Higher scores indicate better body awareness. The Turkish version has been validated and found to be reliable.
Body Awareness Rating Questionnaire
Time frame: up to 6 months
To assess body awareness,the Body Awareness Rating Questionnaire will be used. Body Awareness Rating Questionnaire:This questionnaire includes 24 items across 4 domains: function, mood, feeling/sensation, and awareness. Higher scores indicate better body awareness. The Turkish version has been validated and shown to be reliable.
Upper Extremity Functionality-Grip strength
Time frame: up to 6 months
Grip strength will be measured with a Jamar dynamometer. It will be performed three times bilaterally, and average values (kg) will be recorded.
Upper Extremity Functionality-Pinch strength
Time frame: up to 6 months
Pinch strengths will be assessed using a Baseline pinch gauge. It will be performed three times bilaterally, and average values (kg) will be recorded.
Upper Extremity Functionality-Nine Hole Peg Test (9HPT)
Time frame: up to 6 months
The 9HPT will evaluate hand dexterity by timing how quickly participants place and remove nine pegs. Each hand will be tested three times. It will be recorded in seconds. An average time ≥33.3 seconds will indicate dysfunction in MS patients.
Trunk Stabilization- Trunk Impairment Scale (TIS),
Time frame: up to 6 months
Trunk stabilization will be evaluated using the TIS.TIS: Assesses static/dynamic balance and trunk coordination (17 items, 0-23 points).
Trunk Stabilization-plank endurance test
Time frame: up to 6 months
Trunk stabilization will be evaluated using the plank endurance test. The test measures core endurance. Plank test: Time held in forearm plank recorded. It will be recorded in seconds.
Trunk Stabilization-side bridge test
Time frame: up to 6 months
Trunk stabilization will be evaluated using the side bridge test. The test measures core endurance Time held in side plank on both sides recorded.It will be recorded in seconds.
Trunk Stabilization-Modified Biering-Sorensen
Time frame: up to 6 months
Trunk stabilization will be evaluated using the Modified Biering-Sorensen test. The test measures core endurance. Time holding trunk in horizontal position prone over table edge. It will be recorded in seconds.
Trunk Stabilization-Trunk flexor test
Time frame: up to 6 months
Trunk stabilization will be evaluated using the Trunk flexor test test.The test measures core endurance. Time maintaining 60° trunk flexion with knees/hips at 90°. It will be recorded in seconds.
Trunk Stabilization-Sit up test
Time frame: up to 6 months
The 30-second Sit-up Test measures core strength. The person lies on their back with knees bent and feet on the floor. They do as many sit-ups as possible in 30 seconds, keeping proper form. The score is the number of correct sit-ups completed.
Trunk Stabilization-Modifiye push up test
Time frame: up to 6 months
The 30-second Modified Push-up Test measures core strength. The person starts in a push-up position but with knees on the floor. They perform as many push-ups as possible in 30 seconds, keeping the body straight and lowering the chest close to the ground. The score is the number of correct push-ups completed.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Sep 2026.
- Individual participant dataSharing planned: No
Related trials for Multiple Sclerosis
RecruitingPhase 1
A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders
B-cell Mediated Autoimmune Disorders
RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity
Multiple Sclerosis Spasticity
RecruitingPhase 3
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Multiple Sclerosis (MS) Primary Progressive
Active, not recruiting
Tai Chi Training for Persons With Multiple Sclerosis.
Multiple Sclerosis (MS) - Relapsing-remitting
RecruitingPhase 3
A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis
Secondary Progressive Multiple Sclerosis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Muhammed Kılınç principal investigator
Hacettepe University
Özge Onursal Kılınç study director
Hacettepe University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Multiple Sclerosis, run by Hacettepe University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Güngör Beyza Özvar Şenöz (5053888617 ext. +90, beyzaozvar@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Body Awareness Questionnaire (time frame: up to 6 months). The study lists 12 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Sep 2026.