PsoriasisNCT07154420
Periodontal Health and Quality of Life in Psoriasis Patients
An observational study of Psoriasis and Periodontal Diseases, run by Saglik Bilimleri Universitesi at 1 site in Turkey (Türkiye).
Trial summary
This study aims to evaluate the relationship between psoriasis, a chronic inflammatory skin disease, and oral health. We will assess the periodontal (gum) condition of patients with psoriasis and examine how it affects their quality of life. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Psoriasis, Periodontal Diseases
- What is being tested?
- Diagnostic Test: Periodontal Examination
- How many people
- 226 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 20 Apr 2025to 20 Jul 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Participants aged 18 to 65 years, clinically diagnosed with active psoriasis, and applying to the Dermatology and Venereal Diseases Department outpatient clinic of the Gulhane Faculty of Medicine were recruited into the test group (n=113). The control group consisted of healthy individuals without any dermatological or systemic diseases (n=113).
Who may be able to join
- Participants aged 18 to 65 years
- Clinically diagnosed with active psoriasis
- The presence of at least 12 teeth (excluding third molars)
- Absence of contraindications for periodontal clinical examination
Who cannot join
- Other dermatological conditions
- Pregnancy or lactation
- Antibiotic use within the last 3 months
- Chemotherapy or radiotherapy within the last year
- Periodontal treatment within the last 6 months
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Periodontal Status and Quality of Life in Patients With Psoriasis: A Cross-Sectional Study
This study aims to evaluate the relationship between psoriasis, a chronic inflammatory skin disease, and oral health. We will assess the periodontal (gum) condition of patients with psoriasis and examine how it affects their quality of life. A group of psoriasis patients and a control group without psoriasis will undergo oral examinations and complete a short questionnaire. The goal is to better understand whether psoriasis has an impact on gum health and daily well-being.
- Conditions
- Psoriasis, Periodontal Diseases
- Being tested
- Diagnostic Test: Periodontal Examination
- Keywords
- psoriasis,periodontitis
- Medical subject headings
- Psoriasis, Periodontal Diseases, Periodontitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Diagnostic Test: Periodontal ExaminationDiagnostic test
Diagnostic Test: Periodontal Examination
Diagnostic Test: Periodontal ExaminationDiagnostic test
Periodontal Examination
| Study group | Role | What they receive |
|---|---|---|
| psoriasis patient group | Not described Receives: Diagnostic Test: Diagnostic Test: Periodontal Examination | |
| healthy control group | Not described Receives: Diagnostic Test: Diagnostic Test: Periodontal Examination |
What is being measured
The primary outcome is the main question the study is designed to answer.
Evaluation of oral health-related quality of life in psoriasis patients
The Turkish version of the OHIP-14 questionnaire was administered through face-to-face interviews by a single investigator (G.U.), who was blinded to the periodontal status of the participants. The OHIP-14 consists of seven subscales, each including two items: functional limitation, physical pain, psychological discomfort, physical disability, psychological disability, social disability, and handicap. Participants rated the frequency of negative experiences on a five-point Likert scale (0 = never, 1 = rarely, 2 = occasionally, 3 = quite often, 4 = very often). The total score ranges from 0 to 56, with higher scores reflecting a greater negative impact on oral health-related quality of life
Measured: Baseline
Secondary outcomes (1)
Evaluation of dermatology-specific quality of life in psoriasis patients
Psoriasis Quality of Life Questionnaire (PQLQ) measures functional limitation, physical discomfort, psychological distress, social maladjustment, and disability. Each item was scored on a Likert-type scale, with higher scores reflecting a greater impact on daily life.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Sep 2025
- Study start20 Apr 2025
- Primary completion20 Jul 2025
- Study completion20 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PsoriasisStudies of the same condition, open and under way.
- More trials run by Saglik Bilimleri UniversitesiThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 226 participants (actual)
Sponsor and investigators
- Lead sponsor
- Saglik Bilimleri Universitesi
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Gülbahar Ustaoğlu, Saglik Bilimleri Universitesi
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07154420
- Sponsor's protocol ID
- GUSTAOGLU
- Status last verified
- Aug 2025
- First submitted
- 19 Aug 2025
- Last updated
- 4 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Periodontal Status and Quality of Life in Patients With Psoriasis: A Cross-Sectional Study
- ClinicalTrials.gov ID
- NCT07154420
- Acronym / sponsor ID
- GUSTAOGLU
- Conditions
- Psoriasis, Periodontal Diseases
- Keywords
- psoriasis,periodontitis
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 226 participants (actual)
- Lead sponsor
- Saglik Bilimleri UniversitesiUniversity, hospital or other
- Study start
- 20 Apr 2025 (actual)
- Primary completion
- 20 Jul 2025 (actual)
- Study completion
- 20 Jul 2025 (actual)
- First posted
- 4 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the relationship between psoriasis, a chronic inflammatory skin disease, and oral health. We will assess the periodontal (gum) condition of patients with psoriasis and examine how it affects their quality of life. A group of psoriasis patients and a control group without psoriasis will undergo oral examinations and complete a short questionnaire. The goal is to better understand whether psoriasis has an impact on gum health and daily well-being.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| psoriasis patient group | – | Diagnostic Test: Diagnostic Test: Periodontal Examination |
| healthy control group | – | Diagnostic Test: Diagnostic Test: Periodontal Examination |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Participants aged 18 to 65 years, clinically diagnosed with active psoriasis, and applying to the Dermatology and Venereal Diseases Department outpatient clinic of the Gulhane Faculty of Medicine were recruited into the test group (n=113). The control group consisted of healthy individuals without any dermatological or systemic diseases (n=113).
Key inclusion criteria (4 listed)
- Participants aged 18 to 65 years
- Clinically diagnosed with active psoriasis
- The presence of at least 12 teeth (excluding third molars)
- Absence of contraindications for periodontal clinical examination
Key exclusion criteria (5 listed)
- Other dermatological conditions
- Pregnancy or lactation
- Antibiotic use within the last 3 months
- Chemotherapy or radiotherapy within the last year
- Periodontal treatment within the last 6 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Diagnostic Test: Periodontal ExaminationDiagnostic Test: Periodontal Examination | Diagnostic test | healthy control group, psoriasis patient group |
| Diagnostic Test: Periodontal ExaminationPeriodontal Examination | Diagnostic test | healthy control group, psoriasis patient group |
Primary outcome
Evaluation of oral health-related quality of life in psoriasis patients
Time frame: Baseline
The Turkish version of the OHIP-14 questionnaire was administered through face-to-face interviews by a single investigator (G.U.), who was blinded to the periodontal status of the participants. The OHIP-14 consists of seven subscales, each including two items: functional limitation, physical pain, psychological discomfort, physical disability, psychological disability, social disability, and handicap. Participants rated the frequency of negative experiences on a five-point Likert scale (0 = never, 1 = rarely, 2 = occasionally, 3 = quite often, 4 = very often). The total score ranges from 0 to 56, with higher scores reflecting a greater negative impact on oral health-related quality of life
1 secondary outcome
Evaluation of dermatology-specific quality of life in psoriasis patients
Time frame: Baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Sep 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Psoriasis and Periodontal Diseases, run by Saglik Bilimleri Universitesi at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Evaluation of oral health-related quality of life in psoriasis patients (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Sep 2025.