Infective EndocarditisNCT07156292
The Epidemiology Change From 2006 to 2022 of Infective Endocarditis in Taiwan
An observational study of Infective Endocarditis, run by National Taiwan University Hospital at 1 site in Taiwan.
Trial summary
Infective endocarditis has long been one of the significant diseases causing death and disability worldwide. Its incidence has shown an increasing trend over the past few decades. Moreover, there seems to be significant variation in prevalence and epidemiology in different geographic regions and countries. Read more about this study
- Who is it for?
- Ages Up to 18 years
- Conditions the study is for
- Infective Endocarditis
- What is being tested?
- Observational study, not interventional
- How many people
- 2,247 participants
- Where
- 1 siteTaiwan
- Study dates
- 8 Nov 2023to 31 Dec 2025
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Up to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Study population: Patients who were discharged from hospital or received an emergency diagnosis of infective endocarditis between January 1, 2006 and December 31, 2022
Who may be able to join
- Patients who were discharged from hospital or received an emergency diagnosis of infective endocarditis between January 1, 2006 and December 31, 2022
Who cannot join
- Patients without infective endocarditis
Trial locations and contacts
1 site in 1 country.
About this study
Infective endocarditis has long been one of the significant diseases causing death and disability worldwide. Its incidence has shown an increasing trend over the past few decades. Moreover, there seems to be significant variation in prevalence and epidemiology in different geographic regions and countries. This study aims to understand the trends and changes in the epidemiology of infective endocarditis in Taiwan from the 2006s to the present. Through a retrospective database analysis using the "Taiwan Healthcare System Integration Database," the goal is to improve the prognosis of infective endocarditis treatment in Taiwan.
- Conditions
- Infective Endocarditis
- Being tested
- Observational study, not interventional
- Keywords
- Infective endocarditis, epidemiology, 2006 to 2022
- Medical subject headings
- Endocarditis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Observational study, not interventionalOther
Observational study, not interventional
What is being measured
The primary outcome is the main question the study is designed to answer.
Recent epidemiological trends and changes in infective endocarditis in Taiwan over the past decades
Measured: 2006 to 2022
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Sep 2025
- Study start8 Nov 2023
- Primary completion31 Dec 2025 (estimated)
- Study completion31 Dec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Infective EndocarditisStudies of the same condition, open and under way.
- More trials run by National Taiwan University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 2,247 participants (actual)
Sponsor and investigators
- Lead sponsor
- National Taiwan University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, National Taiwan University Clinical Trial Center, National Taiwan University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07156292
- Sponsor's protocol ID
- 202309097RINB
- Status last verified
- Apr 2025
- First submitted
- 28 Apr 2025
- Last updated
- 5 Sep 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: local epidemiology in order
Study at a glance
From the registry record, last updated by the sponsor on 5 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Epidemiology Change From 2006 to 2022 of Infective Endocarditis in Taiwan
- ClinicalTrials.gov ID
- NCT07156292
- Acronym / sponsor ID
- 202309097RINB
- Conditions
- Infective Endocarditis
- Keywords
- Infective endocarditis, epidemiology, 2006 to 2022
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 2,247 participants (actual)
- Lead sponsor
- National Taiwan University HospitalUniversity, hospital or other
- Study start
- 8 Nov 2023 (actual)
- Primary completion
- 31 Dec 2025 (estimated)
- Study completion
- 31 Dec 2025 (estimated)
- First posted
- 5 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Infective endocarditis has long been one of the significant diseases causing death and disability worldwide. Its incidence has shown an increasing trend over the past few decades. Moreover, there seems to be significant variation in prevalence and epidemiology in different geographic regions and countries. This study aims to understand the trends and changes in the epidemiology of infective endocarditis in Taiwan from the 2006s to the present. Through a retrospective database analysis using the "Taiwan Healthcare System Integration Database," the goal is to improve the prognosis of infective endocarditis treatment in Taiwan.
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
Who may qualify
- Ages
- Up to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
- Study population
- Patients who were discharged from hospital or received an emergency diagnosis of infective endocarditis between January 1, 2006 and December 31, 2022
Key inclusion criteria (1 listed)
- Patients who were discharged from hospital or received an emergency diagnosis of infective endocarditis between January 1, 2006 and December 31, 2022
Key exclusion criteria (1 listed)
- Patients without infective endocarditis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Observational study, not interventionalObservational study, not interventional | Other | – |
Primary outcome
Recent epidemiological trends and changes in infective endocarditis in Taiwan over the past decades
Time frame: 2006 to 2022
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Sep 2025.
- Individual participant dataSharing planned: Yes. local epidemiology in order
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Infective Endocarditis, run by National Taiwan University Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 5 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Recent epidemiological trends and changes in infective endocarditis in Taiwan over the past decades (time frame: 2006 to 2022). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Sep 2025.