Post-traumatic Stress SymptomsNCT07160933
Development of a Psychosocial Intervention to Reduce Post Traumatic Stress in Young Adult Survivors of Cancer
A study testing Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young Adults in people with Post-traumatic Stress Symptoms, run by Zeba Ahmad, Ph.D. at 1 site in United States.
Trial summary
The goal of this study is to develop a virtual group intervention to address post-traumatic stress related to cancer in young adult cancer survivors (YACs, aged 18-39). The study team will do this by integrating evidence-guided treatments and expert clinician feedback (N=10) on the content, delivery, and structure of… Read more about this study
- Who is it for?
- Ages 18 to 39 years
- Conditions the study is for
- Post-traumatic Stress Symptoms
- What is being tested?
- Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young Adults
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Sep 2026to 30 Jun 2030
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 39 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
None listed.
Who cannot join
- Unable to provide verbal consent
- Reporting active symptoms of psychosis that preclude safe participation.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Mass General Cancer Center
Boston, Massachusetts, 02114
Blane Zhu, B.S., (617) 726-5130, xzhu@mgh.harvard.edu
Zeba N Ahmad, Ph.D.
About this study
Official title: Adaptation and Refinement of a Psychosocial Intervention to Reduce Post-Traumatic Stress in Young Adult Survivors of Cancer
The goal of this study is to develop a virtual group intervention to address post-traumatic stress related to cancer in young adult cancer survivors (YACs, aged 18-39). The study team will do this by integrating evidence-guided treatments and expert clinician feedback (N=10) on the content, delivery, and structure of the intervention. Next, the study team will refine this intervention through a pilot trial with a group of YACs (N=80).
- Conditions
- Post-traumatic Stress Symptoms
- Being tested
- Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young Adults
- Keywords
- young adult cancer survivors, cancer-related post-traumatic stress, post-traumatic stress
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young AdultsBehavioural
A new group-based virtual intervention to address post-traumatic stress related to cancer in YACs, integrating evidence-guided treatments from Cognitive Processing Therapy and Mind-Body Resiliency interventions.
| Study group | Role | What they receive |
|---|---|---|
| Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young Adults | Experimental | The study team aims to evaluate the feasibility and acceptability of the adapted psychosocial intervention through a pilot trial with a group of 80 YACs, followed by mixed-methods data analysis of feasibility and acceptability outcomes. Receives: Behavioral: Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young Adults |
What is being measured
The primary outcome is the main question the study is designed to answer.
Intervention Feasibility: Percent of Identified Prospective Participants Who Enroll
Percent of eligible participants who were offered participation and who enroll in the study by completing consent and baseline assessment.
Measured: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Intervention Feasibility: Proportion of Participants Completing the Program
Percent of enrolled participants who complete the program, defined as completing 6 out of 8 sessions.
Measured: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Intervention Acceptability
Acceptability will be assessed by the Client Satisfaction Questionnaire (CSQ-8). The intervention study will be considered acceptable if ≥80% of participants rate it as acceptable (defined as a CSQ-8 score ≥20).
Measured: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Sep 2025
- Study start1 Sep 2026 (estimated)
- Primary completion30 Jun 2030 (estimated)
- Study completion30 Jun 2030 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Post-traumatic Stress SymptomsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Zeba Ahmad, Ph.D.
- Sponsor type
- University, hospital or other
- Collaborators
- American Cancer Society, Inc.
- Responsible party
- Sponsor-investigator, Zeba Ahmad, Ph.D., Massachusetts General Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07160933
- Sponsor's protocol ID
- 25-306
- Other IDs
- CSDG-24-1319592-01-CTPS
- Status last verified
- Aug 2026
- First submitted
- 29 Aug 2025
- Last updated
- 18 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Adaptation and Refinement of a Psychosocial Intervention to Reduce Post-Traumatic Stress in Young Adult Survivors of Cancer
- ClinicalTrials.gov ID
- NCT07160933
- Acronym / sponsor ID
- 25-306
- Conditions
- Post-traumatic Stress Symptoms
- Keywords
- young adult cancer survivors, cancer-related post-traumatic stress, post-traumatic stress
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Zeba Ahmad, Ph.D.University, hospital or other
- Collaborators
- American Cancer Society, Inc.
- Study start
- 1 Sep 2026 (estimated)
- Primary completion
- 30 Jun 2030 (estimated)
- Study completion
- 30 Jun 2030 (estimated)
- First posted
- 8 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to develop a virtual group intervention to address post-traumatic stress related to cancer in young adult cancer survivors (YACs, aged 18-39). The study team will do this by integrating evidence-guided treatments and expert clinician feedback (N=10) on the content, delivery, and structure of the intervention. Next, the study team will refine this intervention through a pilot trial with a group of YACs (N=80).
Study design
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young Adults | Experimental | Behavioral: Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young AdultsThe study team aims to evaluate the feasibility and acceptability of the adapted psychosocial intervention through a pilot trial with a group of 80 YACs, followed by mixed-methods data analysis of feasibility and acceptability outcomes. |
Who may qualify
- Ages
- 18 to 39 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (0 listed)
Key exclusion criteria (2 listed)
- Unable to provide verbal consent
- Reporting active symptoms of psychosis that preclude safe participation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young AdultsA new group-based virtual intervention to address post-traumatic stress related to cancer in YACs, integrating evidence-guided treatments from Cognitive Processing Therapy and Mind-Body Resiliency interventions. | Behavioural | Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young Adults |
Primary outcome
Intervention Feasibility: Percent of Identified Prospective Participants Who Enroll
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Percent of eligible participants who were offered participation and who enroll in the study by completing consent and baseline assessment.
Intervention Feasibility: Proportion of Participants Completing the Program
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Percent of enrolled participants who complete the program, defined as completing 6 out of 8 sessions.
Intervention Acceptability
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Acceptability will be assessed by the Client Satisfaction Questionnaire (CSQ-8). The intervention study will be considered acceptable if ≥80% of participants rate it as acceptable (defined as a CSQ-8 score ≥20).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Psychosocial Intervention for Cancer-Related Post-Traumatic Stress in Young Adults in people with Post-traumatic Stress Symptoms, run by Zeba Ahmad, Ph.D. at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 0 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 18 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Zeba N Ahmad, Ph.D. (617-724-1586, zahmad2@mgh.harvard.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Intervention Feasibility: Percent of Identified Prospective Participants Who Enroll (time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Aug 2026; AzTrials last refreshed its copy on 6 Nov 2026.