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ColonoscopyNCT07171853

The Carbon Footprint Study of Colonoscopy

An observational study of Colonoscopy, run by King Chulalongkorn Memorial Hospital at 1 site in Thailand.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

With global warming intensifying, GI endoscopy is among the top three greenhouse gas-emitting medical procedures. Colonoscopy, a cornerstone for colorectal cancer (CRC) screening, significantly contributes to the carbon footprint (CF). Read more about this study

Who is it for?
Ages 18 to 80 years
Conditions the study is for
Colonoscopy
How many people
362 participants
Where
1 siteThailand
Study dates
1 Oct 2025to 30 Apr 2026
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 80 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: Patients aged 18-80 years who received a colonoscopy at King Chulalongkorn Memorial Hospital

Who may be able to join

  • Patients aged 18-80 years

Who cannot join

  • Patient status grade III-V according to the American Society of Anesthesiologists (ASA)
  • Poor bowel preparation (grade <6 in the Boston Bowel Preparation Scale [BBPS])
  • Endoscopic JNET type III or suspicion of malignancy
  • Hematologic or coagulation disorders, Plt<140,000/mcL, INR>1.5
  • anti-platelet/anticoagulant medication that could not be paused as recommended in the current guideline
  • Emergency colonoscopy, GI bleeding, unstable vital sign, critical ill patient
Show all 12Show fewer
  • Inflammatory bowel disease
  • Pregnancy
  • Severe cardiopulmonary disease
  • Severe infection
  • Malignancy
  • History of allergy to IV sedative medication

Trial locations and contacts

1 site in 1 country.

Thailand1 site
  • King Chulalongkorn Memorial Hospital

    Bangkok, Bangkok, 10330

Other trials in Thailand

About this study

Official title: The Carbon Footprint Study of Colonoscopy for Colorectal Cancer Screening and Various Techniques of Colonic Polypectomy

With global warming intensifying, GI endoscopy is among the top three greenhouse gas-emitting medical procedures. Colonoscopy, a cornerstone for colorectal cancer (CRC) screening, significantly contributes to the carbon footprint (CF). This study quantifies CO₂ emissions in different steps of colonoscopy and evaluates the environmental impact of common polypectomy techniques to establish baseline CF data and identify opportunities for mitigation. This study included patients undergoing colonoscopy for CRC screening. CO₂ emissions were comprehensively measured at each step of the procedure (pre-, during, and post-colonoscopy), including energy consumption, all equipment and medications, waste management, and endoscopy reprocessing. Emission data were also collected for common polypectomy techniques, including cold forceps biopsy (CFB), cold snare polypectomy (CSP), hot snare polypectomy (HSP), and hot snare endoscopic mucosal resection (EMR), all performed according to standard polypectomy protocols.

Read the detailed description

Global warming refers to the long-term increase in Earth's average surface temperature, primarily caused by the buildup of greenhouse gases in the atmosphere due to human activities. The carbon footprint of a colonoscopy refers to the total greenhouse gas emissions (primarily CO₂ equivalents) generated throughout the procedure. While colonoscopy for colon cancer screening improves survival outcomes, it still contributes to environmental impact through energy use, medical supplies, and waste. Calculating a carbon footprint involves estimating the total greenhouse gas emissions, usually expressed in carbon dioxide equivalents (CO₂e).

Main formula : Carbon footprint (CO₂e) = Activity Data × Emission Factor

Carbon footprint assessment is a tool for assessing the magnitude of greenhouse gas emissions from public health care processes for planning, developing and systematically improving public health systems to reduce carbon footprints leading to environmental sustainability.

Carbon footprint measurement in this study

  1. Volunteers underwent bowel preparation by taking laxatives until their stool appearance met the clear criteria. The amount of laxative taken was recorded.
  2. A nurse conducted a medical history interview using a standardized safety checklist before the colonoscopy, measured the patient's vital signs, and established intravenous access for administering medication or fluids.
  3. Research participants were fitted with a nasal oxygen delivery device and given intravenous sedatives to induce an appropriate level of sedation. Vital signs and fingertip oxygen saturation levels were monitored before starting the colonoscopy.
  4. During the colonoscopy, the nurse monitored vital signs and oxygen saturation periodically and adjusted the sedative dosage based on the patient's level of consciousness.
  5. Patients underwent colonoscopy for colorectal cancer screening and diagnosis. If a colonic polyp was found, it was removed according to clinical indications and current treatment guidelines. The size of the polyp was estimated visually by comparing it with the size of the resection instrument. In the event of bleeding or perforation, endoscopic procedures were performed as indicated for treatment. During the procedure, all equipment used, the volume of water, the type and amount of sedative medication, and the duration of the colonoscopy and colonic polypectomy were recorded for subsequent carbon footprint analysis.
  6. The removed colonic polyp tissue was preserved in a formalin-containing specimen jar for pathological examination by a pathologist.
  7. After the colonoscopy, the patient was transferred to a recovery room, where vital signs were monitored periodically until the participant regained full consciousness.
  8. After polypectomy, the patient resumed antiplatelet and anticoagulant medications according to the timing recommended by standard clinical guidelines.

The data from the patient's intake of laxatives for bowel preparation through to the completion of the colonoscope cleaning process was recorded and analyzed to calculate the carbon footprint in collaboration with the faculty team from the Environmental Research Institute of Chulalongkorn University.

Conditions
Colonoscopy
Keywords
Carbon footprint, Colonoscopy, Colonic polypectomy

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Study groups in NCT07171853
Study groupRoleWhat they receive
Diagnostic ColonoscopyPatient receiving diagnostic colonoscopy for colorectal cancer screening without therapeutic intervention
Colonoscopy with colonic polypectomyPatient receiving colonoscopy with various techniques of colonic polypectomy

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Carbon footprint of normal screening colonoscopy

    Mean carbon footprint, expressed as kgCO₂e per procedure, calculated across the pre-endoscopic, endoscopic, and post-endoscopic phases.

    Measured: From bowel preparation ingestion through completion of endoscope reprocessing for each colonoscopy procedure.

  2. Incremental carbon footprint according to colonic polypectomy technique

    Mean incremental carbon footprint, expressed as kgCO₂e per resected polyp, for cold forceps biopsy, cold snare polypectomy, hot snare polypectomy, and endoscopic mucosal resection.

    Measured: From insertion of the polypectomy device through completion of polyp removal and specimen retrieval for each resected polyp.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted15 Sep 2025
  2. Study start1 Oct 2025
  3. Primary completion30 Apr 2026
  4. Study completion30 Apr 2026

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
362 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07171853
Sponsor's protocol ID
RP028
Status last verified
Aug 2026
First submitted
6 Sep 2025
Last updated
4 Aug 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Publications

  • Steubing B, de Koning A, Merciai S, Tukker A. How do carbon footprints from LCA and EEIOA databases compare? A comparison of ecoinvent and EXIOBASE. Journal of Industrial Ecology. 2022;26(4):1406-22.

  • Turner DA, Williams ID, Kemp S. Greenhouse gas emission factors for recycling of source-segregated waste materials. Resources, Conservation and Recycling. 2015;105:186-97.

  • McGinnis S, Johnson-Privitera C, Nunziato JD, Wohlford S. Environmental Life Cycle Assessment in Medical Practice: A User's Guide. Obstet Gynecol Surv. 2021 Jul;76(7):417-428. doi: 10.1097/OGX.0000000000000906.

    PubMed 34324694
  • Sevigne-Itoiz E, Mwabonje O, Panoutsou C, Woods J. Life cycle assessment (LCA): informing the development of a sustainable circular bioeconomy? Philos Trans A Math Phys Eng Sci. 2021 Sep 20;379(2206):20200352. doi: 10.1098/rsta.2020.0352. Epub 2021 Aug 2.

    PubMed 34334023
  • Yu X, Tan C. China's process-related greenhouse gas emission dataset 1990-2020. Sci Data. 2023 Jan 25;10(1):55. doi: 10.1038/s41597-023-01957-y.

    PubMed 36697420
  • Rodriguez de Santiago E, Dinis-Ribeiro M, Pohl H, Agrawal D, Arvanitakis M, Baddeley R, Bak E, Bhandari P, Bretthauer M, Burga P, Donnelly L, Eickhoff A, Hayee B, Kaminski MF, Karlovic K, Lorenzo-Zuniga V, Pellise M, Pioche M, Siau K, Siersema PD, Stableforth W, Tham TC, Triantafyllou K, Tringali A, Veitch A, Voiosu AM, Webster GJ, Vienne A, Beilenhoff U, Bisschops R, Hassan C, Gralnek IM, Messmann H. Reducing the environmental footprint of gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastroenterology and Endoscopy Nurses and Associates (ESGENA) Position Statement. Endoscopy. 2022 Aug;54(8):797-826. doi: 10.1055/a-1859-3726. Epub 2022 Jul 8.

    PubMed 35803275
  • Vaccari M, Tudor T, Perteghella A. Costs associated with the management of waste from healthcare facilities: An analysis at national and site level. Waste Manag Res. 2018 Jan;36(1):39-47. doi: 10.1177/0734242X17739968. Epub 2017 Nov 14.

    PubMed 29132259
  • Ferlitsch M, Hassan C, Bisschops R, Bhandari P, Dinis-Ribeiro M, Risio M, Paspatis GA, Moss A, Libanio D, Lorenzo-Zuniga V, Voiosu AM, Rutter MD, Pellise M, Moons LMG, Probst A, Awadie H, Amato A, Takeuchi Y, Repici A, Rahmi G, Koecklin HU, Albeniz E, Rockenbauer LM, Waldmann E, Messmann H, Triantafyllou K, Jover R, Gralnek IM, Dekker E, Bourke MJ. Colorectal polypectomy and endoscopic mucosal resection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2024. Endoscopy. 2024 Jul;56(7):516-545. doi: 10.1055/a-2304-3219. Epub 2024 Apr 26.

    PubMed 38670139
  • Iwatate M, Sano Y, Tanaka S, Kudo SE, Saito S, Matsuda T, Wada Y, Fujii T, Ikematsu H, Uraoka T, Kobayashi N, Nakamura H, Hotta K, Horimatsu T, Sakamoto N, Fu KI, Tsuruta O, Kawano H, Kashida H, Takeuchi Y, Machida H, Kusaka T, Yoshida N, Hirata I, Terai T, Yamano HO, Nakajima T, Sakamoto T, Yamaguchi Y, Tamai N, Nakano N, Hayashi N, Oka S, Ishikawa H, Murakami Y, Yoshida S, Saito Y; Japan NBI Expert Team (JNET). Validation study for development of the Japan NBI Expert Team classification of colorectal lesions. Dig Endosc. 2018 Sep;30(5):642-651. doi: 10.1111/den.13065. Epub 2018 Jun 26.

    PubMed 29603399
  • The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002. Gastrointest Endosc. 2003 Dec;58(6 Suppl):S3-43. doi: 10.1016/s0016-5107(03)02159-x. No abstract available.

    PubMed 14652541
  • ASGE Standards of Practice Committee; Early DS, Ben-Menachem T, Decker GA, Evans JA, Fanelli RD, Fisher DA, Fukami N, Hwang JH, Jain R, Jue TL, Khan KM, Malpas PM, Maple JT, Sharaf RS, Dominitz JA, Cash BD. Appropriate use of GI endoscopy. Gastrointest Endosc. 2012 Jun;75(6):1127-31. doi: 10.1016/j.gie.2012.01.011. No abstract available.

    PubMed 22624807
  • Cunha Neves JA, Rodriguez de Santiago E, Aabakken L. Approaches for greening endoscopy and reducing waste. Gut. 2023 Nov 24;72(12):2204-2206. doi: 10.1136/gutjnl-2023-330917. No abstract available.

    PubMed 37977580
  • Brown JJ, Asumeng CK, Greenwald D, Weissman M, Zauber A, Striplin J, Weng O, List JM, Farley SM, Winawer SJ. Decreased colorectal cancer incidence and mortality in a diverse urban population with increased colonoscopy screening. BMC Public Health. 2021 Jun 30;21(1):1280. doi: 10.1186/s12889-021-11330-6.

    PubMed 34193094
  • Doubeni CA, Corley DA, Quinn VP, Jensen CD, Zauber AG, Goodman M, Johnson JR, Mehta SJ, Becerra TA, Zhao WK, Schottinger J, Doria-Rose VP, Levin TR, Weiss NS, Fletcher RH. Effectiveness of screening colonoscopy in reducing the risk of death from right and left colon cancer: a large community-based study. Gut. 2018 Feb;67(2):291-298. doi: 10.1136/gutjnl-2016-312712. Epub 2016 Oct 12.

    PubMed 27733426
  • Han J, Tan Z, Chen M, Zhao L, Yang L, Chen S. Carbon Footprint Research Based on Input-Output Model-A Global Scientometric Visualization Analysis. Int J Environ Res Public Health. 2022 Sep 9;19(18):11343. doi: 10.3390/ijerph191811343.

    PubMed 36141618

Questions about this trial

What is this clinical trial studying?

An observational study of Colonoscopy, run by King Chulalongkorn Memorial Hospital at 1 site in Thailand.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 4 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Carbon footprint of normal screening colonoscopy (time frame: From bowel preparation ingestion through completion of endoscope reprocessing for each colonoscopy procedure.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07171853, which also lists 22 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Aug 2026.

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