FrailNCT07176520
AI-Assisted Rehabilitation In Frailty
A study testing AI-assisted rehabilitation in people with Frail, run by SingHealth Community Hospitals.
Trial summary
This study investigates the effectiveness and implementation of an AI-assisted rehabilitation tool for adults with frailty in the real-world. The main questions it aims to answer are: Does AI-assisted rehabilitation among frail adults improve patients' physical outcomes? Is there a particular subgroup of frail… Read more about this study
- Who is it for?
- Ages 21 to 120 years
- Conditions the study is for
- Frail
- What is being tested?
- AI-assisted rehabilitation
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 220 participants
- Where
- No sites listed yet
- Study dates
- 1 Dec 2025to 30 Apr 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 to 120 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults aged ≥ 21years
- Clinical Frailty Score (CFS) 4 to 6 *
- Provided informed consent (for cognitively impaired persons MMSE<18, next-of-kin or proxy to give consent).
- Have access to smartphone/tablet (own or loaned from investigators)/
Who cannot join
- Medical conditions precluding safe home exercises or severely affect interaction with AI-tool (angina, vision loss, hearing impairment).
- Cognitive impairment (MMSE<18) and no caregiver to assist with use of tool.
- Participation in structured outpatient physiotherapy (>1 times/week), or day rehab programme.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: AI-Assisted Rehabilitation for Frail Older Adults Discharged From Community Hospitals: A Hybrid Effectiveness-Implementation Trial
This study investigates the effectiveness and implementation of an AI-assisted rehabilitation tool for adults with frailty in the real-world. The main questions it aims to answer are:
Does AI-assisted rehabilitation among frail adults improve patients' physical outcomes? Is there a particular subgroup of frail subjects that will benefit most from AI-assisted rehabilitation?
Read more
Researchers will compare AI-assisted rehabilitation to standard practice (advice and QR link for rehabilitation videos to be done at home) to see if AI-assisted rehabilitation improves clinical outcomes compared to standard practice.
Participants will either:
Undergo an AI-assisted rehab with the AI-sensor tool or a standard practice post-discharge from community hospitals for 12 weeks.
Undergo interval assessments of outcomes. Keep a diary of outpatient rehabilitations (if applicable for the subjects).
Read the detailed description
This is a pragmatic, randomized controlled study on frail patients discharged from three community hospitals in Singapore.
- Conditions
- Frail
- Being tested
- AI-assisted rehabilitation, usual care only
- Keywords
- hybrid effectiveness-implementation study, pragmatic
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
AI-assisted rehabilitationDevice
Receives AI-assisted rehabilitation post-discharge at home in addition to usual care
usual care onlyOther
Verbal and written discharge summary, advice, and referral to outpatient physiotherapy (if applicable)
| Study group | Role | What they receive |
|---|---|---|
| Usual care | Other | Verbal and written discharge summary, advice, and referral to outpatient physiotherapy (if applicable) Receives: Other: usual care only |
| AI-assisted rehabilitation | Active comparator | AI-assisted rehabilitation on top of usual care Receives: Device: AI-assisted rehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Absolute Functional Gain (AFG)
AFG= Functional score (at discharge/follow-up points) - functional score (at admission). Functional score is based on Modified Barthel Index (MBI).
Measured: baseline, 3, 6, 9 and 12 weeks.
Secondary outcomes (1)
Functional outcome: Short Physical Performance Battery (SPBB)
SPBB is a validated and commonly used tool to evaluate physical performance particularly in older adults. It is based on three timed tasks: gait speed (over short distance of 4 metres), balance tests (side-by-side, semi-tandem, and full-tandem), and repetitive chair sit-to-stand (strength and endurance) performance.45 It is an indicator of vulnerability, is associated with readmissions, and predictive of all-cause mortality.
Measured: baseline, 3, 6, 9, 12-weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Sep 2025
- Study start1 Dec 2025 (estimated)
- Primary completion31 Jan 2027 (estimated)
- Study completion30 Apr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for FrailStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Care provider, Investigator, Outcomes assessor
- Enrolment
- 220 participants (estimated)
Sponsor and investigators
- Lead sponsor
- SingHealth Community Hospitals
- Sponsor type
- University, hospital or other
- Collaborators
- Jurong Community Hospital, Singapore
- Responsible party
- Principal investigator, Ong Chong Yau, SingHealth Community Hospitals
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07176520
- Sponsor's protocol ID
- 2025-1300
- Status last verified
- Sep 2025
- First submitted
- 9 Sep 2025
- Last updated
- 16 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: In accordance to my ethical board and institutional requirements.
Study at a glance
From the registry record, last updated by the sponsor on 16 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- AI-Assisted Rehabilitation for Frail Older Adults Discharged From Community Hospitals: A Hybrid Effectiveness-Implementation Trial
- ClinicalTrials.gov ID
- NCT07176520
- Acronym / sponsor ID
- 2025-1300
- Conditions
- Frail
- Keywords
- hybrid effectiveness-implementation study, pragmatic
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 220 participants (estimated)
- Lead sponsor
- SingHealth Community HospitalsUniversity, hospital or other
- Collaborators
- Jurong Community Hospital, Singapore
- Study start
- 1 Dec 2025 (estimated)
- Primary completion
- 31 Jan 2027 (estimated)
- Study completion
- 30 Apr 2027 (estimated)
- First posted
- 16 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study investigates the effectiveness and implementation of an AI-assisted rehabilitation tool for adults with frailty in the real-world. The main questions it aims to answer are:
Does AI-assisted rehabilitation among frail adults improve patients' physical outcomes? Is there a particular subgroup of frail subjects that will benefit most from AI-assisted rehabilitation?
Researchers will compare AI-assisted rehabilitation to standard practice (advice and QR link for rehabilitation videos to be done at home) to see if AI-assisted rehabilitation improves clinical outcomes compared to standard practice.
Participants will either:
Undergo an AI-assisted rehab with the AI-sensor tool or a standard practice post-discharge from community hospitals for 12 weeks.
Undergo interval assessments of outcomes. Keep a diary of outpatient rehabilitations (if applicable for the subjects).
Detailed description
This is a pragmatic, randomized controlled study on frail patients discharged from three community hospitals in Singapore.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (care provider, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Usual care | Other | Other: usual care onlyVerbal and written discharge summary, advice, and referral to outpatient physiotherapy (if applicable) |
| AI-assisted rehabilitation | Active comparator | Device: AI-assisted rehabilitationAI-assisted rehabilitation on top of usual care |
Who may qualify
- Ages
- 21 to 120 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Adults aged ≥ 21years
- Clinical Frailty Score (CFS) 4 to 6 *
- Provided informed consent (for cognitively impaired persons MMSE<18, next-of-kin or proxy to give consent).
- Have access to smartphone/tablet (own or loaned from investigators)/
Key exclusion criteria (3 listed)
- Medical conditions precluding safe home exercises or severely affect interaction with AI-tool (angina, vision loss, hearing impairment).
- Cognitive impairment (MMSE<18) and no caregiver to assist with use of tool.
- Participation in structured outpatient physiotherapy (>1 times/week), or day rehab programme.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| AI-assisted rehabilitationReceives AI-assisted rehabilitation post-discharge at home in addition to usual care | Device | AI-assisted rehabilitation |
| usual care onlyVerbal and written discharge summary, advice, and referral to outpatient physiotherapy (if applicable) | Other | Usual care |
Primary outcome
Absolute Functional Gain (AFG)
Time frame: baseline, 3, 6, 9 and 12 weeks.
AFG= Functional score (at discharge/follow-up points) - functional score (at admission). Functional score is based on Modified Barthel Index (MBI).
1 secondary outcome
Functional outcome: Short Physical Performance Battery (SPBB)
Time frame: baseline, 3, 6, 9, 12-weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Sep 2025.
- Individual participant dataSharing planned: No. In accordance to my ethical board and institutional requirements.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing AI-assisted rehabilitation in people with Frail, run by SingHealth Community Hospitals.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 16 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Chong Yau Clinical Asst Professor, MBBS (6569703000, ong.chong.yau@singhealth.com.sg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Absolute Functional Gain (AFG) (time frame: baseline, 3, 6, 9 and 12 weeks.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Sep 2025.