Skin SaggingNCT07188051
Ovolux Beauty From Within Trial#2
A study testing Ovolux brand eggshell membrane powder in people with Skin Sagging and Skin Wrinkling, run by ESM Technologies, LLC at 1 site in United States.
Trial summary
The purpose of this study is to evaluate the effectiveness of an eggshell membrane dietary supplement (Ovolux brand) in supporting beauty from within. Read more about this study
- Who is it for?
- Ages 35 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Skin Sagging, Skin Wrinkling, Skin Dryness
- What is being tested?
- Ovolux brand eggshell membrane powder
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 100 participants
- Where
- 1 siteUnited States
- Study dates
- 22 Sep 2025to 25 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Participant is willing and able to read, understand, and provide written Informed Consent and Photo Release.
- Participant is a healthy female or male, aged 35 through 65 years (inclusive).
- Participant is willing and able to swallow capsules.
- Participant has self-perceived facial wrinkles and facial sagging skin.
- Participant is seeking improvements to hair and nails such as hair growth and thickness and nail strength and appearance.
- Participant agrees to keep their hair at least 3 inches long.
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- Participant is willing to comply with all study procedures and attend all study visits.
- Participant agrees not to have any hair cosmetic procedures such as relaxers or perms, etc. while on the study. Coloring/dyeing is permitted if part of the participant's regular routine and this routine is maintained during the study.
- Participant is willing to forego taking any hair, nail or skin supplements or using/applying any other hair, nail or skin products on their hair/scalp, nails or face that promote nail or hair growth or are collagen boosting for the duration of the study.
- Participant is willing to discontinue any hair or nail or collagen boosting dietary or nutritional supplements two weeks before the onset of the study and for the study duration. Dietary supplements such as a general multi-vitamin, vitamins A, C or D, iron or calcium are acceptable.
- Participant agrees not to wet their face or consume hot or cold or caffeine containing foods or beverages within 2 hours of all visits.
- Participant reviewed the ingredient list for the test article (dietary supplement) and the placebo and, to the best of their knowledge, confirmed they have no sensitivity or allergy to the ingredients.
- Females of child bearing potential must agree to use an adequate method of birth control, which include: systemic birth control (must have been on the same type of systemic birth control for at least 3 months prior starting the study and must not change the type of birth control during the study); diaphragm with spermicide, condom with spermicide; IUD (hormonal or copper); Vasectomized partner; bilateral tubal ligation; or Abstinence. Females who are post-menopausal (absence of menses for at least 1 year), have had a hysterectomy or have had a bilateral oophorectomy do not need any additional birth control are considered to be not of childbearing potential; (Confirmed by verbal response only).
Who cannot join
- Participant is allergic to eggs or egg proteins.
- Participant is a smoker.
- Participant has a current skin disease on or near the scalp (e.g., eczema, psoriasis) or anywhere else on the body.
- Participant has any allergies or sensitivities to any dietary or nutritional supplements or their ingredients.
- Participant has artificial nails (press-on, glue-on, gel, acrylic, etc.). Nail polish is permitted if part of regular nail routine and if this routine is maintained during the study.
- Participation in another supplement study in the past 30 days.
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- Participant has dreads or weaves.
- Participant has had any chemical hair procedure (used relaxers, perms, etc.) in the last 8 weeks.
- Participant has dyed their hair within the last 3 days.
- Participant has a diagnosed hair loss disorder such as alopecia areata, scarring alopecia, and/or androgenetic alopecia and/or pattern baldness.
- Participant is taking or using any medications or supplements (over the counter or prescription, topical or oral) for hair growth such as minoxidil, finasteride, dutasteride, spironolactone, collagen, amino acids, keratin, biotin, rosemary oil, corticosteroid injections, etc. or treatments for hair growth such as laser treatment or supplements for nails or skin.
- Participant is under treatment by a medical professional for a hair/scalp, nail or skin condition.
- Participant has any concomitant skin diseases of the scalp or skin such as atopic dermatitis, seborrheic dermatitis, psoriasis, eczema, tinea capitis, etc. or irritation such as rash, sores, etc. on the scalp.
- Participant has an infestation on the scalp such as lice.
- Female Only: Participant is pregnant, planning to become pregnant during the course of the study or nursing (self-reported).
- Participant has been diagnosed with chronic skin allergies.
- Current use of OTC pain medication ingested in quantities exceeding label use.
- Participant has been diagnosed with any type of cancer especially skin cancer within the past 12 months or treated for cancer in the last 5 years.
- Participant is routinely using any anti-inflammatories, and/or antihistamines.
- Participant has a history of any chronic diseases such as insulin dependent diabetes, HIV/AIDS, etc.
- Participant has any medical condition or is taking a medication that would compromise the safety of the participant or preclude participation in the study per the Principal Investigator.
- Participant is currently participating in another clinical trial involving the skin, scalp or hair or nails.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Princeton Consumer Research Corp.
Cincinnati, Ohio, 45239
About this study
Official title: A 12 Week Clinical Study to Evaluate the Effects of an Eggshell Membrane Dietary Supplement on Elasticity and Skin Hydration Versus Placebo
The purpose of this study is to evaluate the effectiveness of an eggshell membrane dietary supplement (Ovolux brand) in supporting beauty from within.
Read the detailed description
The objective of this study is to evaluate the dietary supplement, Ovolux brand eggshell membrane, versus a placebo control for potential effects on facial skin elasticity, hydration, and wrinkles, and hair attributes using bioinstrumentation (Corneometer, Cutometer), imaging (VISIA CR Imaging, HairMetrix analysis) and subjective evaluation of hair, nail and facial skin condition over 12 weeks.
- Conditions
- Skin Sagging, Skin Wrinkling, Skin Dryness
- Being tested
- Ovolux brand eggshell membrane powder, Placebo
- Keywords
- ovolux, eggshell membrane, beauty, skin elasticity, wrinkles, hair, fingernails
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ovolux brand eggshell membrane powderDietary supplement
Unhydrolyzed eggshell membrane powder
PlaceboDietary supplement
psyllium husk fiber powder
| Study group | Role | What they receive |
|---|---|---|
| Active | Experimental | Active intervention (Ovolux) Receives: Dietary Supplement: Ovolux brand eggshell membrane powder |
| Placebo | Placebo comparator | Placebo Receives: Dietary Supplement: Placebo |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Skin Elasticity
Measurement of facial skin elasticity parameters (R0, R2, R5, R6 and R9) via Cutometer® to determine if it improves or worsens
Measured: Baseline, Week 4, Week 8, and Week 12
Secondary outcomes (4)
Change in Skin Hydration
Measurement of facial skin hydration via Corneometer® to determine if it improves or worsens
Measured: Baseline, Week 4, Week 8, and Week 12
Change in Hair Thickness/Density
Trichoscopy to evaluate hair attributes using D200evo Dermatoscope with HairMetrix® to determine if thickness/density improves or worsens
Measured: Baseline, Week 12
Change in Skin Wrinkles
VISIA images will be collected for analysis of facial wrinkles to determine if wrinkling improves or worsens
Measured: Baseline and Week 12
Participant Self-Assessment Questionnaires
Self-Assessment Questionnaires for skin, hair, \& fingernail quality completed by participants. Each scale ranges from zero (poor) to ten (excellent). Higher scores equate to a better outcome.
Measured: Baseline, Week 4, Week 8, and Week 12
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Sep 2025
- Study start22 Sep 2025
- Primary completion31 Jan 2026 (estimated)
- Study completion25 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Skin SaggingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Single-center, randomized, double-blinded, placebo controlled design
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- ESM Technologies, LLC
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- Princeton Consumer Research Corporation
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07188051
- Sponsor's protocol ID
- STNCLI1Q
- Status last verified
- Dec 2025
- First submitted
- 10 Sep 2025
- Last updated
- 18 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A 12 Week Clinical Study to Evaluate the Effects of an Eggshell Membrane Dietary Supplement on Elasticity and Skin Hydration Versus Placebo
- ClinicalTrials.gov ID
- NCT07188051
- Acronym / sponsor ID
- STNCLI1Q
- Conditions
- Skin Sagging, Skin Wrinkling, Skin Dryness
- Keywords
- ovolux, eggshell membrane, beauty, skin elasticity, wrinkles, hair, fingernails
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- ESM Technologies, LLCIndustry (pharma, biotech, devices)
- Collaborators
- Princeton Consumer Research Corporation
- Study start
- 22 Sep 2025 (actual)
- Primary completion
- 31 Jan 2026 (estimated)
- Study completion
- 25 Feb 2026 (estimated)
- First posted
- 23 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to evaluate the effectiveness of an eggshell membrane dietary supplement (Ovolux brand) in supporting beauty from within.
Detailed description
The objective of this study is to evaluate the dietary supplement, Ovolux brand eggshell membrane, versus a placebo control for potential effects on facial skin elasticity, hydration, and wrinkles, and hair attributes using bioinstrumentation (Corneometer, Cutometer), imaging (VISIA CR Imaging, HairMetrix analysis) and subjective evaluation of hair, nail and facial skin condition over 12 weeks.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- Single-center, randomized, double-blinded, placebo controlled design
| Arm | Type | Receives |
|---|---|---|
| Active | Experimental | Dietary Supplement: Ovolux brand eggshell membrane powderActive intervention (Ovolux) |
| Placebo | Placebo comparator | Dietary Supplement: PlaceboPlacebo |
Who may qualify
- Ages
- 35 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (13 listed)
- Participant is willing and able to read, understand, and provide written Informed Consent and Photo Release.
- Participant is a healthy female or male, aged 35 through 65 years (inclusive).
- Participant is willing and able to swallow capsules.
- Participant has self-perceived facial wrinkles and facial sagging skin.
- Participant is seeking improvements to hair and nails such as hair growth and thickness and nail strength and appearance.
Key exclusion criteria (22 listed)
- Participant is allergic to eggs or egg proteins.
- Participant is a smoker.
- Participant has a current skin disease on or near the scalp (e.g., eczema, psoriasis) or anywhere else on the body.
- Participant has any allergies or sensitivities to any dietary or nutritional supplements or their ingredients.
- Participant has artificial nails (press-on, glue-on, gel, acrylic, etc.). Nail polish is permitted if part of regular nail routine and if this routine is maintained during the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ovolux brand eggshell membrane powderUnhydrolyzed eggshell membrane powder | Dietary supplement | Active |
| Placebopsyllium husk fiber powder | Dietary supplement | Placebo |
Primary outcome
Change in Skin Elasticity
Time frame: Baseline, Week 4, Week 8, and Week 12
Measurement of facial skin elasticity parameters (R0, R2, R5, R6 and R9) via Cutometer® to determine if it improves or worsens
4 secondary outcomes
Change in Skin Hydration
Time frame: Baseline, Week 4, Week 8, and Week 12
Change in Hair Thickness/Density
Time frame: Baseline, Week 12
Change in Skin Wrinkles
Time frame: Baseline and Week 12
Participant Self-Assessment Questionnaires
Time frame: Baseline, Week 4, Week 8, and Week 12
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Dec 2025.
- Individual participant dataSharing planned: No
Related trials for Skin Sagging
Recruiting
Clinical Evaluation of a Multi-functional Beauty Device on Cosmetic Skin Outcomes
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Enrolling by invitation
Safety and Efficacy of Matrix Pro for Eyebrow Lift and Lift of Submental/Neck Laxity
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Recruiting
Study to Evaluate the Safety and Efficacy of the Cytrellis Micro-Coring Device for the Treatment of Moderate to Severe Facial Wrinkles
Wrinkle
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ovolux brand eggshell membrane powder in people with Skin Sagging and Skin Wrinkling, run by ESM Technologies, LLC at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 13 inclusion and 22 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 18 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Skin Elasticity (time frame: Baseline, Week 4, Week 8, and Week 12). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Dec 2025.