Peroneal NeuropathyNCT07191301
Functional Strength Training and Kinesiotaping, With and Without Proprioceptive Neuromuscular Facilitation in Fibular (Peroneal) Neuropathy
A study testing Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular Facilitation and Functional Strength Training and Kinesio Taping in people with Peroneal Neuropathy, run by University of Lahore at 1 site in Pakistan.
Trial summary
Fibular neuropathy frequently manifests as foot drop, muscle weakness, altered gait, and sensory loss, all of which severely reduce mobility and quality of life. There is still uncertainty regarding the efficacy of kinesio taping (KT), proprioceptive neuromuscular facilitation (PNF), and functional strength training… Read more about this study
- Who is it for?
- Ages 18 to 35 years
- Conditions the study is for
- Peroneal Neuropathy
- What is being tested?
- Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular Facilitation and Functional Strength Training and Kinesio Taping
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 48 participants
- Where
- 1 sitePakistan
- Study dates
- 10 Aug 2025to 30 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- • Adults (18-35 years old) are diagnosed with fibular neuropathy due to trauma or compression.
- Patients with muscle weakness, impaired balance and abnormal gait.
- Both Male and female participants will be included.
- Patients who test positive to the drag or slap test will be considered positive if the patient have difficulty in lifting the forefoot while walking, leading to dragging of the toes or compensatory hip/knee movements.
Who cannot join
- • Recent foot or ankle surgery (<6 months).
- Complete loss of nerve supply
- Severe musculoskeletal or neurological conditions (Amyotrophic lateral sclerosis, multiple sclerosis, myopathies, severe osteoarthritis, severe compression, progressive neuropathies, severe balance and fall risk, Guillain-Barré Syndrome (GBS) and peripheral vascular diseases).
- Allergies to Kinesio tape materials.
- Patients who are not psychologically fit such as those who have undergone trauma and patients with severe psychological disorders (major depressive disorder, PTSD, schizophrenia) will be excluded if they have had a diagnosis within the last 6 months.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: "Functional Strength Training and Kinesiotaping With and Without Proprioceptive Neuromuscular Facilitation Technique in Fibular (Peroneal) Neuropathy"
Fibular neuropathy frequently manifests as foot drop, muscle weakness, altered gait, and sensory loss, all of which severely reduce mobility and quality of life. There is still uncertainty regarding the efficacy of kinesio taping (KT), proprioceptive neuromuscular facilitation (PNF), and functional strength training (FST) in combination. Although PNF improves neuromuscular coordination, KT provides proprioceptive input, and FST increases strength and mobility, there are no set treatment guidelines and little research has compared these modalities. In order to contribute to evidence-based rehabilitation techniques for people with fibular neuropathy, this study attempts to assess whether adding PNF to FST and KT improves functional outcomes compared to FST and KT alone.
- Conditions
- Peroneal Neuropathy
- Being tested
- Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular Facilitation, Functional Strength Training and Kinesio Taping
- Medical subject headings
- Peroneal Neuropathies
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular FacilitationBehavioural
Participants will undergo 8 weeks of supervised treatment, 3 sessions per week (24 sessions). Each session includes a warm-up with stretches, range-of-motion exercises, and Functional Strength Training (mini hops, stair climbing, ramp walking, sit-to-stand). Kinesio Taping will be applied from the foot's dorsum along the tibialis anterior and peroneus longus with 25-50% stretch for ankle support and dorsiflexor facilitation, re-applied every 3-4 days. In addition, Proprioceptive Neuromuscular Facilitation (PNF) lower-limb D1 flexion/extension patterns with manual resistance will be performed in 3 sets of 5 repetitions, lasting 35-40 minutes per session.
Functional Strength Training and Kinesio TapingBehavioural
Participants will undergo 8 weeks of supervised treatment, 3 sessions per week (24 sessions). Each session includes a warm-up with stretches, range-of-motion exercises, and Functional Strength Training (mini hops, stair climbing, ramp walking, sit-to-stand). Kinesio Taping will be applied from the foot's dorsum along the tibialis anterior and peroneus longus with 25-50% stretch for ankle support and dorsiflexor facilitation, re-applied every 3-4 days. No PNF techniques will be applied.
| Study group | Role | What they receive |
|---|---|---|
| Interventional Group A | Experimental | Functional Strength Training (FST) + Kinesio Taping (KT) with Proprioceptive Neuromuscular Facilitation (PNF). Receives: Behavioral: Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular Facilitation; Behavioral: Functional Strength Training and Kinesio Taping |
| Control Group B | Active comparator | Functional Strength Training (FST) + Kinesio Taping (KT) without PNF. Receives: Behavioral: Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular Facilitation; Behavioral: Functional Strength Training and Kinesio Taping |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in dorsiflexor muscle strength measured by Manual Muscle Grading (MMG)
Measured: Baseline (Week 0), Mid-point (Week 4), and Post-intervention (Week 8)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Sep 2025
- Study start10 Aug 2025
- Primary completion10 Dec 2025
- Study completion30 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Peroneal NeuropathyStudies of the same condition, open and under way.
- More trials run by University of LahoreThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 48 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sumayyah Farooq, University of Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07191301
- Sponsor's protocol ID
- Sumayah Farooq
- Status last verified
- Mar 2026
- First submitted
- 17 Sep 2025
- Last updated
- 5 Mar 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- "Functional Strength Training and Kinesiotaping With and Without Proprioceptive Neuromuscular Facilitation Technique in Fibular (Peroneal) Neuropathy"
- ClinicalTrials.gov ID
- NCT07191301
- Acronym / sponsor ID
- Sumayah Farooq
- Conditions
- Peroneal Neuropathy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 48 participants (actual)
- Lead sponsor
- University of LahoreUniversity, hospital or other
- Study start
- 10 Aug 2025 (actual)
- Primary completion
- 10 Dec 2025 (actual)
- Study completion
- 30 Dec 2025 (actual)
- First posted
- 24 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Fibular neuropathy frequently manifests as foot drop, muscle weakness, altered gait, and sensory loss, all of which severely reduce mobility and quality of life. There is still uncertainty regarding the efficacy of kinesio taping (KT), proprioceptive neuromuscular facilitation (PNF), and functional strength training (FST) in combination. Although PNF improves neuromuscular coordination, KT provides proprioceptive input, and FST increases strength and mobility, there are no set treatment guidelines and little research has compared these modalities. In order to contribute to evidence-based rehabilitation techniques for people with fibular neuropathy, this study attempts to assess whether adding PNF to FST and KT improves functional outcomes compared to FST and KT alone.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Interventional Group A | Experimental | Behavioral: Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular Facilitation, Behavioral: Functional Strength Training and Kinesio TapingFunctional Strength Training (FST) + Kinesio Taping (KT) with Proprioceptive Neuromuscular Facilitation (PNF). |
| Control Group B | Active comparator | Behavioral: Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular Facilitation, Behavioral: Functional Strength Training and Kinesio TapingFunctional Strength Training (FST) + Kinesio Taping (KT) without PNF. |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- • Adults (18-35 years old) are diagnosed with fibular neuropathy due to trauma or compression.
Key exclusion criteria (5 listed)
- • Recent foot or ankle surgery (<6 months).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular FacilitationParticipants will undergo 8 weeks of supervised treatment, 3 sessions per week (24 sessions). Each session includes a warm-up with stretches, range-of-motion exercises, and Functional Strength Training (mini hops, stair climbing, ramp walking, sit-to-stand). Kinesio Taping will be applied from the foot's dorsum along the tibialis anterior and peroneus longus with 25-50% stretch for ankle support and dorsiflexor facilitation, re-applied every 3-4 days. In addition, Proprioceptive Neuromuscular Facilitation (PNF) lower-limb D1 flexion/extension patterns with manual resistance will be performed in 3 sets of 5 repetitions, lasting 35-40 minutes per session. | Behavioural | Control Group B, Interventional Group A |
| Functional Strength Training and Kinesio TapingParticipants will undergo 8 weeks of supervised treatment, 3 sessions per week (24 sessions). Each session includes a warm-up with stretches, range-of-motion exercises, and Functional Strength Training (mini hops, stair climbing, ramp walking, sit-to-stand). Kinesio Taping will be applied from the foot's dorsum along the tibialis anterior and peroneus longus with 25-50% stretch for ankle support and dorsiflexor facilitation, re-applied every 3-4 days. No PNF techniques will be applied. | Behavioural | Control Group B, Interventional Group A |
Primary outcome
Change in dorsiflexor muscle strength measured by Manual Muscle Grading (MMG)
Time frame: Baseline (Week 0), Mid-point (Week 4), and Post-intervention (Week 8)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular Facilitation and Functional Strength Training and Kinesio Taping in people with Peroneal Neuropathy, run by University of Lahore at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in dorsiflexor muscle strength measured by Manual Muscle Grading (MMG) (time frame: Baseline (Week 0), Mid-point (Week 4), and Post-intervention (Week 8)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Mar 2026.