Moderate to Severe Endodontic PainNCT07192146
Patient Reported Outcomes and Associated Factors Following Endodontic Emergency Treatment
An observational study of Moderate to Severe Endodontic Pain, run by Chulalongkorn University at 1 site in Thailand.
Trial summary
This study aims to analyze the improvement of postoperative pain and Oral Health-Related Quality of Life (OHRQoL) following endodontic emergency treatment, as well as the contributing factors affecting the change including age, gender, tooth type, dental arch, pulpal status, percussion pain, radiographic evidence of… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Moderate to Severe Endodontic Pain
- How many people
- 70 participants
- Where
- 1 siteThailand
- Study dates
- 17 Aug 2023to Oct 2025
- How long will I take part?
- 7 Days
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients undergo endodontic emergency treatment.
Who may be able to join
- Age 18 years or older
- Presence of moderate to severe pain as measured by a Numerical Rating Scale (NRS) score ≥ 4
- Pain of endodontic origin confirmed through clinical and/or radiographic examination
Who cannot join
- Refused or were unable to provide informed consent or complete the questionnaire
- Were currently or recently taking immunosuppressive agents, long-term anti-inflammatory medications, or antibiotics
- Had non-endodontic or mixed-origin pain
- Had already initiated endodontic treatment on the affected tooth
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Thailand1 site, 1 recruiting
- Recruiting
Faculty of Dentistry, Chulalongkorn University
Bangkok, 10330
Pantira Thep-akrapong, 66813730370, pantira.mew@gmail.com
Chanakarn Sinsareekul, 66832759760, chanakarn.si@chula.ac.th
About this study
Official title: Patient Reported Outcomes and Associated Factors Following Endodontic Emergency Treatment: A Prospective Cohort Study
This study aims to analyze the improvement of postoperative pain and Oral Health-Related Quality of Life (OHRQoL) following endodontic emergency treatment, as well as the contributing factors affecting the change including age, gender, tooth type, dental arch, pulpal status, percussion pain, radiographic evidence of periapical lesions, type of emergency treatment (pulpotomy / partial pulpectomy / complete pulpectomy), and occlusal adjustment.
- Conditions
- Moderate to Severe Endodontic Pain
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative pain
Higher scores mean a worse outcome.
Measured: From enrollment to the end of treatment at 2 years
Secondary outcomes (1)
Oral health-related quality of life
Higher scores mean a worse outcome.
Measured: From enrollment to the end of treatment at 2 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Sep 2025
- Study start17 Aug 2023
- Primary completion28 Apr 2025
- Study completionOct 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Moderate to Severe Endodontic PainStudies of the same condition, open and under way.
- More trials run by Chulalongkorn UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 70 participants (estimated)
- Target duration
- 7 Days
Sponsor and investigators
- Lead sponsor
- Chulalongkorn University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07192146
- Sponsor's protocol ID
- HREC-DCU 2023-122
- Status last verified
- Jul 2025
- First submitted
- 20 Jul 2025
- Last updated
- 25 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 25 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Patient Reported Outcomes and Associated Factors Following Endodontic Emergency Treatment: A Prospective Cohort Study
- ClinicalTrials.gov ID
- NCT07192146
- Acronym / sponsor ID
- HREC-DCU 2023-122
- Conditions
- Moderate to Severe Endodontic Pain
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 70 participants (estimated)
- Lead sponsor
- Chulalongkorn UniversityUniversity, hospital or other
- Study start
- 17 Aug 2023 (actual)
- Primary completion
- 28 Apr 2025 (actual)
- Study completion
- Oct 2025 (estimated)
- First posted
- 25 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to analyze the improvement of postoperative pain and Oral Health-Related Quality of Life (OHRQoL) following endodontic emergency treatment, as well as the contributing factors affecting the change including age, gender, tooth type, dental arch, pulpal status, percussion pain, radiographic evidence of periapical lesions, type of emergency treatment (pulpotomy / partial pulpectomy / complete pulpectomy), and occlusal adjustment.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 7 Days
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients undergo endodontic emergency treatment.
Key inclusion criteria (3 listed)
- Age 18 years or older
- Presence of moderate to severe pain as measured by a Numerical Rating Scale (NRS) score ≥ 4
- Pain of endodontic origin confirmed through clinical and/or radiographic examination
Key exclusion criteria (4 listed)
- Refused or were unable to provide informed consent or complete the questionnaire
- Were currently or recently taking immunosuppressive agents, long-term anti-inflammatory medications, or antibiotics
- Had non-endodontic or mixed-origin pain
- Had already initiated endodontic treatment on the affected tooth
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Postoperative pain
Time frame: From enrollment to the end of treatment at 2 years
Higher scores mean a worse outcome.
1 secondary outcome
Oral health-related quality of life
Time frame: From enrollment to the end of treatment at 2 years
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Sep 2025.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Moderate to Severe Endodontic Pain, run by Chulalongkorn University at 1 site in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 25 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Pantira Thep-akrapong (66813730370, pantira.mew@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative pain (time frame: From enrollment to the end of treatment at 2 years). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Sep 2025.