Knee Pain ChronicNCT07194031
The Acute Effects of Ankle Exercises on Knee Proprioception
A study testing Ankle Exercise and Knee Exercise in people with Knee Pain Chronic, run by Gaziantep Islam Science and Technology University at 1 site in Turkey (Türkiye).
Trial summary
The goal of this randomized research study is to investigate the acute effects of ankle exercises on improving knee proprioception and pain in individuals with knee pain, aged 18-70, who receive intervention-based ankle and knee exercises to treat their knee pain. Read more about this study
- Who is it for?
- Ages 18 to 70 years
- Conditions the study is for
- Knee Pain Chronic
- What is being tested?
- Ankle Exercise and Knee Exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 114 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 6 Jan 2025to 20 Jun 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- The participants who have a VAS pain score >5,
- The participants who have experienced knee pain for the last six months or longer,
- The participants who volunteered to participate in the study
Who cannot join
- Individuals who had undergone knee and ankle surgery within the last year
- Individuals who have a VAS pain score below 5
- Individuals who are experiencing ROM limitations in the knee or ankle
- Individuals who have a neurological pathology in the lower extremity
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Gaziantep Islam Science and Technology University
Gaziantep
About this study
Official title: The Acute Effects of Ankle Exercises on Knee Proprioception and Pain in Individuals With Knee Pain
The goal of this randomized research study is to investigate the acute effects of ankle exercises on improving knee proprioception and pain in individuals with knee pain, aged 18-70, who receive intervention-based ankle and knee exercises to treat their knee pain. The main question it aims to answer is:
- Does ankle exercise affect knee joint proprioception and pain in individuals with knee pain? Researchers will compare ankle exercise (the intervention) with knee exercise (as part of their regular medical care for knee pain) to determine if ankle exercise is effective in improving knee joint proprioception and reducing pain.
Participants will be asked to do exercises and to let the researchers take their measurements.
- Conditions
- Knee Pain Chronic
- Being tested
- Ankle Exercise, Knee Exercise
- Keywords
- Ankle, Exercise, Knee, Pain, Proprioception
- Medical subject headings
- Motor Activity, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ankle ExerciseOther
Also called Plantar flexion
In the literature, studies have evaluated ankle proprioception following interventions applied to the knee. However, no studies report the effects of ankle exercises on knee proprioception
Knee ExerciseOther
Also called Knee flexion-extension
The literature emphasizes that long-term and multidirectional exercise programs provide proprioceptive improvements
| Study group | Role | What they receive |
|---|---|---|
| Knee exercise | Active comparator | Knee flexion-extension Receives: Other: Knee Exercise |
| Ankle exercise | Experimental | Ankle plantar flexion with body weight Receives: Other: Ankle Exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
Knee proprioception
Knee flexion- extension position
Measured: 4 weeks
Secondary outcomes (1)
Knee pain
Visual Analogue Scale (VAS); Zero, no pain; 10 worst pain
Measured: 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Sep 2025
- Study start6 Jan 2025
- Primary completion30 May 2025
- Study completion20 Jun 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee Pain ChronicStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Ankle- Knee Exercises
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 114 participants (actual)
Sponsor and investigators
- Lead sponsor
- Gaziantep Islam Science and Technology University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Gönül Elpeze, Gaziantep Islam Science and Technology University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07194031
- Sponsor's protocol ID
- KNEE PROPRİOCEPTİON
- Status last verified
- Sep 2025
- First submitted
- 10 Sep 2025
- Last updated
- 26 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Acute Effects of Ankle Exercises on Knee Proprioception and Pain in Individuals With Knee Pain
- ClinicalTrials.gov ID
- NCT07194031
- Acronym / sponsor ID
- KNEE PROPRİOCEPTİON
- Conditions
- Knee Pain Chronic
- Keywords
- Ankle, Exercise, Knee, Pain, Proprioception
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 114 participants (actual)
- Lead sponsor
- Gaziantep Islam Science and Technology UniversityUniversity, hospital or other
- Study start
- 6 Jan 2025 (actual)
- Primary completion
- 30 May 2025 (actual)
- Study completion
- 20 Jun 2025 (actual)
- First posted
- 26 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this randomized research study is to investigate the acute effects of ankle exercises on improving knee proprioception and pain in individuals with knee pain, aged 18-70, who receive intervention-based ankle and knee exercises to treat their knee pain. The main question it aims to answer is:
- Does ankle exercise affect knee joint proprioception and pain in individuals with knee pain? Researchers will compare ankle exercise (the intervention) with knee exercise (as part of their regular medical care for knee pain) to determine if ankle exercise is effective in improving knee joint proprioception and reducing pain.
Participants will be asked to do exercises and to let the researchers take their measurements.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Ankle- Knee Exercises
| Arm | Type | Receives |
|---|---|---|
| Knee exercise | Active comparator | Other: Knee ExerciseKnee flexion-extension |
| Ankle exercise | Experimental | Other: Ankle ExerciseAnkle plantar flexion with body weight |
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- The participants who have a VAS pain score >5,
- The participants who have experienced knee pain for the last six months or longer,
- The participants who volunteered to participate in the study
Key exclusion criteria (4 listed)
- Individuals who had undergone knee and ankle surgery within the last year
- Individuals who have a VAS pain score below 5
- Individuals who are experiencing ROM limitations in the knee or ankle
- Individuals who have a neurological pathology in the lower extremity
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ankle ExerciseAlso: Plantar flexionIn the literature, studies have evaluated ankle proprioception following interventions applied to the knee. However, no studies report the effects of ankle exercises on knee proprioception | Other | Ankle exercise |
| Knee ExerciseAlso: Knee flexion-extensionThe literature emphasizes that long-term and multidirectional exercise programs provide proprioceptive improvements | Other | Knee exercise |
Primary outcome
Knee proprioception
Time frame: 4 weeks
Knee flexion- extension position
1 secondary outcome
Knee pain
Time frame: 4 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Sep 2025.
- Individual participant dataSharing planned: No
Related trials for Knee Pain Chronic
Recruiting
BioPoly® Partial Resurfacing Knee Implant IDE
Knee Pain Chronic, Knee Osteoarthritis
RecruitingPhase 2
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Osteoarthritis, Knee, Diabetic Neuropathic Pain
RecruitingPhase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
Osteoarthritis, Knee, Chronic Pain
Not yet recruitingEarly Phase 1
Medication vs. Meditation for Chronic Knee Osteoarthritis
Knee Osteoarthristis
Recruiting
Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.
Chronic Post-surgical Pain, Chronic Post Operative Pain
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ankle Exercise and Knee Exercise in people with Knee Pain Chronic, run by Gaziantep Islam Science and Technology University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Knee proprioception (time frame: 4 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Sep 2025.