Neck PainNCT07196800
Effect of Dose Variations of High-Power Laser Therapy on Patients With Nonspecific Cervical Pain
A study testing High intensity laser therapy (low dose) combined with conventional physiotherapy program and High intensity laser therapy (High dose) combined with conventional physiotherapy program in people with Neck Pain, run by Deraya University at 1 site in Egypt.
Trial summary
Nonspecific neck pain, defined as pain without a specific underlying pathology, is a common musculoskeletal disorder that affects a significant proportion of the global population. Read more about this study
- Who is it for?
- Ages 18 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Neck Pain
- What is being tested?
- High intensity laser therapy (low dose) combined with conventional physiotherapy program and High intensity laser therapy (High dose) combined with conventional physiotherapy program
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Mar 2025to 1 Dec 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- unilateral or bilateral CNP
- Experiencing moderate to severe neck pain, defined as a Visual Analog
- Scale (VAS) score of ≥4.
- Cervical Range of Motion (ROM) Limitation: Documented restriction in cervical ROM compared to normal values for age and gender, to ensure the condition's impact on functional mobility
- Patients agreed not to take any medication(anti-inflammatories, analgesics, or muscle relaxants) throughout the course of the study or receive any type of treatment for neck pain
Who cannot join
- Previous Cervical Surgery: Patients with a history of cervical spine surgery will be excluded to eliminate potential influences from post-surgical changes on the outcomes
- Diagnosed with cervical disc prolapse as confirmed by clinical evaluation and imaging studies (MRI or CT scans).
- History of malignancy in the cervical region or other serious medical conditions.
- Severe comorbidities that may affect treatment outcomes (e.g., uncontrolled diabetes, cardiovascular diseases).
- Pregnancy or lactation.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Deraya university physiotherapy clinic
Minya, 05673
soad Ali, pHD, 01003621641, soad.ali@deraya.edu.eg
Yuosef Alaa Araby, MSc
About this study
Nonspecific neck pain, defined as pain without a specific underlying pathology, is a common musculoskeletal disorder that affects a significant proportion of the global population. Neck pain often results in considerable discomfort and functional limitations, impacting individuals' quality of life and ability to perform daily tasks. Estimates suggest that up to 30% of adults experience neck pain annually. The condition ranks among the top causes of disability worldwide, contributing to substantial personal and societal burdens, including lost work productivity and increased healthcare costs.
- Conditions
- Neck Pain
- Being tested
- High intensity laser therapy (low dose) combined with conventional physiotherapy program, High intensity laser therapy (High dose) combined with conventional physiotherapy program
- Medical subject headings
- Neck Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
High intensity laser therapy (low dose) combined with conventional physiotherapy programRadiation
840 joules delivered during each session combined with conventional physiotherapy program Participants
High intensity laser therapy (High dose) combined with conventional physiotherapy programProcedure or surgery
2632 joules delivered during each session combined with conventional physiotherapy program
| Study group | Role | What they receive |
|---|---|---|
| lower dose laser therapy | Active comparator | Not described Receives: Radiation: High intensity laser therapy (low dose) combined with conventional physiotherapy program |
| higher dose laser therapy | Experimental | Not described Receives: Procedure: High intensity laser therapy (High dose) combined with conventional physiotherapy program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain assessment
where participants will rate their pain on a scale from 0 (no pain) to 10 (worst pain imaginable).
Measured: 4 weeks
Cervical Range of Motion (ROM):
ROM will be measured using an OB goniometer in three planes
Measured: 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Sep 2025
- Study start10 Mar 2025
- Primary completion10 Nov 2025 (estimated)
- Study completion1 Dec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Neck PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Deraya University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07196800
- Sponsor's protocol ID
- physio 2 2025
- Status last verified
- Sep 2025
- First submitted
- 20 Sep 2025
- Last updated
- 29 Sep 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 29 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Dose Variations of High-Power Laser Therapy on Patients With Nonspecific Cervical Pain
- ClinicalTrials.gov ID
- NCT07196800
- Acronym / sponsor ID
- physio 2 2025
- Conditions
- Neck Pain
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Deraya UniversityUniversity, hospital or other
- Study start
- 10 Mar 2025 (actual)
- Primary completion
- 10 Nov 2025 (estimated)
- Study completion
- 1 Dec 2025 (estimated)
- First posted
- 29 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Nonspecific neck pain, defined as pain without a specific underlying pathology, is a common musculoskeletal disorder that affects a significant proportion of the global population. Neck pain often results in considerable discomfort and functional limitations, impacting individuals' quality of life and ability to perform daily tasks. Estimates suggest that up to 30% of adults experience neck pain annually. The condition ranks among the top causes of disability worldwide, contributing to substantial personal and societal burdens, including lost work productivity and increased healthcare costs.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| lower dose laser therapy | Active comparator | Radiation: High intensity laser therapy (low dose) combined with conventional physiotherapy program |
| higher dose laser therapy | Experimental | Procedure: High intensity laser therapy (High dose) combined with conventional physiotherapy program |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- unilateral or bilateral CNP
- Experiencing moderate to severe neck pain, defined as a Visual Analog
- Scale (VAS) score of ≥4.
- Cervical Range of Motion (ROM) Limitation: Documented restriction in cervical ROM compared to normal values for age and gender, to ensure the condition's impact on functional mobility
- Patients agreed not to take any medication(anti-inflammatories, analgesics, or muscle relaxants) throughout the course of the study or receive any type of treatment for neck pain
Key exclusion criteria (5 listed)
- Previous Cervical Surgery: Patients with a history of cervical spine surgery will be excluded to eliminate potential influences from post-surgical changes on the outcomes
- Diagnosed with cervical disc prolapse as confirmed by clinical evaluation and imaging studies (MRI or CT scans).
- History of malignancy in the cervical region or other serious medical conditions.
- Severe comorbidities that may affect treatment outcomes (e.g., uncontrolled diabetes, cardiovascular diseases).
- Pregnancy or lactation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| High intensity laser therapy (low dose) combined with conventional physiotherapy program840 joules delivered during each session combined with conventional physiotherapy program Participants | Radiation | lower dose laser therapy |
| High intensity laser therapy (High dose) combined with conventional physiotherapy program2632 joules delivered during each session combined with conventional physiotherapy program | Procedure or surgery | higher dose laser therapy |
Primary outcome
Pain assessment
Time frame: 4 weeks
where participants will rate their pain on a scale from 0 (no pain) to 10 (worst pain imaginable).
Cervical Range of Motion (ROM):
Time frame: 4 weeks
ROM will be measured using an OB goniometer in three planes
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Sep 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing High intensity laser therapy (low dose) combined with conventional physiotherapy program and High intensity laser therapy (High dose) combined with conventional physiotherapy program in people with Neck Pain, run by Deraya University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 29 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain assessment (time frame: 4 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Sep 2025; AzTrials last refreshed its copy on 7 Nov 2026.