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Hip Pain ChronicMRI USGNCT07198646

Correlation of Ultrasound and MRI Measurements of Quadratus Femoris Thickness and Ischiofemoral Distance in Clinically and Radiologically Diagnosed Ischiofemoral Impingement

An observational study of Hip Pain Chronic and Impingement Syndrome, run by Kutay Can ÇAMLICA at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The goal of this observational study is to evaluate the correlation between ultrasound measurements of quadratus femoris muscle thickness and ischiofemoral distance, as well as clinical parameters, with MRI measurements in patients diagnosed with ischiofemoral impingement (IFI) through MRI imaging and clinical… Read more about this study

Who is it for?
Ages 18 to 65 years
Conditions the study is for
Hip Pain Chronic, Impingement Syndrome
How many people
30 participants
Where
1 siteTurkey (Türkiye)
Study dates
10 Oct 2024to 10 Apr 2025
How long will I take part?
8 Months
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 65 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: 1. Patients older than 18 years and younger than 65 years. 2. Patients diagnosed by MRI 3. Those with a body mass index below 25 kg/m2 4. those with hip pain or positive physical examination tests

Who may be able to join

  • Patients older than 18 years and younger than 65 years.
  • Patients diagnosed by MRI
  • Those with a body mass index below 25 kg/m2
  • those with hip pain or positive physical examination tests

Who cannot join

  • Sciatic nerve damage detected on EMG
  • Patients with operative ischiofemoral decompression
  • Corticosteroid or any injection to the hip in the last 3 months
  • History of peripheral nerve damage
  • Femoroacetabular impingement
  • Pregnancy
Show all 12Show fewer
  • Malignancy
  • Inflammatory pathologies: rheumatic, septic
  • Coxarthrosis-Kelgren-Lawrence grade 3-4
  • Those who have undergone hip arthroplasty/surgery
  • Causes of lumbar radiculopathy, spondylolisthesis
  • Patients with increased femoral anteversion - patients with increased hip internal rotation (Toe-in)

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site
  • Seyrantepe Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey

    Istanbul, sarıyer

Other trials in Turkey (Türkiye)

About this study

Official title: Evaluation of the Correlation of Ultrasound Measurements of Quadratus Femoris Muscle Thickness and Ischiofemoral Distance With MR Measurements in Patients Diagnosed With Ischiofemoral Impingement by MR Imaging and Clinical Examination.

The goal of this observational study is to evaluate the correlation between ultrasound measurements of quadratus femoris muscle thickness and ischiofemoral distance, as well as clinical parameters, with MRI measurements in patients diagnosed with ischiofemoral impingement (IFI) through MRI imaging and clinical examination. The main questions it aims to answer are: Is there a correlation between ultrasound and MRI measurements of quadratus femoris muscle thickness and ischiofemoral distance in patients with clinically and radiologically confirmed IFI? How do clinical parameters relate to ultrasound and MRI findings in these patients? What is the intra- and inter-rater reliability of ultrasound measurements for these parameters? Participants will undergo ultrasound measurement of quadratus femoris muscle thickness and ischiofemoral distance, assessment of clinical parameters related to ischiofemoral impingement, and measurements performed twice by two independent raters to assess intra- and inter-rater reliability. Researchers will compare ultrasound and MRI measurements as well as clinical parameters to determine if ultrasound can serve as a reliable and cost-effective alternative for diagnosing ischiofemoral impingement.

Read the detailed description

Ischiofemoral impingement (IFI) was first described in 1977 by Karl A. Johnson, and his study is widely regarded as the first clinical definition of the syndrome. IFI is defined as an extra-articular hip impingement syndrome resulting from the narrowing of the space between the ischium and the lesser trochanter, leading to compression of the quadratus femoris muscle and surrounding soft tissues, thereby causing clinical symptoms.

IFI findings are associated with edema and irritation of the quadratus femoris muscle, as well as secondary atrophic fatty degeneration in chronic cases. The primary symptom is posterior and lateral hip pain, often exacerbated by physical activity. Due to the close anatomical relationship between the quadratus femoris muscle and the sciatic nerve, irritation of the nerve may lead to pain radiating anteriorly, to the posterior thigh, and distally to the knee.

The etiology of IFI is multifactorial, involving congenital anatomical variations, post-traumatic sequelae, postoperative changes following hip surgery, and primary hip joint pathologies. Additional factors, such as femoral anteversion, acetabular retroversion, and abductor or adductor insufficiencies, may also contribute to its pathogenesis. The exact prevalence of IFI remains unknown, but it has been reported to be more common in females than in males, with a female-to-male ratio of approximately 3:1. This higher incidence in females is attributed to gender differences in pelvic morphology and a narrower ischiofemoral space. While IFI typically affects middle-aged and older adults, it has been observed across a wide age range (30-70 years). Although IFI generally presents unilaterally, bilateral involvement has been reported in 25-40% of cases, with no consensus in the literature regarding side predominance. The diagnosis of IFI requires a combination of detailed patient history, physical examination, and imaging techniques. Clinical tests such as the long-stride walking test and the ischiofemoral impingement test play a significant role in diagnosis, while MRI is considered the gold-standard imaging modality for confirmation.

The present study aims to investigate the correlation between ultrasound measurements and MRI findings in patients diagnosed with IFI through MRI and clinical examination. Specifically, ultrasound measurements of quadratus femoris muscle thickness and ischiofemoral distance will be evaluated for their consistency with MRI findings. Additionally, clinical parameters related to IFI will be assessed to explore their association with imaging results. The primary objective of this study is to determine the feasibility of using ultrasound, a more cost-effective imaging method, as an alternative diagnostic tool for IFI. The hypothesis is that by establishing a reliable correlation between ultrasound and MRI findings, it may be possible to implement a lower-cost and more accessible diagnostic approach for this condition.

Keywords
Ischiofemoral impingement, quadratus femoris compression, hip pain diagnosis, ultrasound-MRI correlation, cost-effective imaging in hip pathology.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Correlation of ultrasonographic ischiofemoral space (IFS) and quadratus femoris muscle thickness with clinical and MRI parameters

    The primary outcome is to determine the relationship between ultrasonographically measured ischiofemoral space (IFS) and quadratus femoris muscle thickness with magnetic resonance imaging (MRI) findings (IFS and quadratus femoris space) and clinical parameters including pain intensity (Visual Analog Scale, VAS) and hip function (Harris Hip Score).

    Measured: Baseline (at enrollment)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted30 Sep 2025
  2. Study start10 Oct 2024
  3. Primary completion10 Mar 2025
  4. Study completion10 Apr 2025

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Case-control
Time perspective
Cross-sectional
Enrolment
30 participants (actual)
Target duration
8 Months
IDs, dates and publications
ClinicalTrials.gov ID
NCT07198646
Sponsor's protocol ID
4500
Acronym
MRI USG
Status last verified
Aug 2024
First submitted
21 Sep 2025
Last updated
30 Sep 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

An observational study of Hip Pain Chronic and Impingement Syndrome, run by Kutay Can ÇAMLICA at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 30 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Correlation of ultrasonographic ischiofemoral space (IFS) and quadratus femoris muscle thickness with clinical and MRI parameters (time frame: Baseline (at enrollment)). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Sep 2025.

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