Prehospital Stroke CareNCT07198893
Impact of Prehospital Stroke Care Patterns on Clinical Outcomes in Acute Stroke Patients
An observational study of Prehospital Stroke Care, run by Assiut University.
Trial summary
This study evaluates how prehospital care factors, including stroke awareness, emergency response, transport, and referral processes, impact patient outcomes in acute stroke cases. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Prehospital Stroke Care
- How many people
- 125 participants
- Where
- No sites listed yet
- Study dates
- 1 Oct 2026to 30 Dec 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Participants are adult patients aged 18 years and above with an acute ischemic or hemorrhagic stroke diagnosis confirmed by neuroimaging. All patients must reside within the defined geographical area and have used emergency medical services or presented directly with stroke symptoms. Caregivers will also provide data regarding symptom recognition and decision-making. Patients with stroke mimics, incomplete records, or without consent will be excluded.
Who may be able to join
- Adults ≥18 years of age
- Confirmed diagnosis of acute stroke (ischemic/hemorrhagic) verified by CT or MRI
- Residents of the study's defined geographical area
- Patients who experienced stroke and sought prehospital care pathways (EMS or direct hospital presentation)
- Informed consent from the patient or legally authorized representative
Who cannot join
- Patients with transient ischemic attack (TIA) or stroke mimics without confirmed acute stroke diagnosis
- Missing or incomplete data on prehospital care
- Patients unable or unwilling to provide consent without a representative available
- Non-residents or visitors outside the designated geographical area
About this study
Official title: Pattern and Impact of Prehospital Stroke Care on Patient Outcome: A Population-Based Study
This study evaluates how prehospital care factors, including stroke awareness, emergency response, transport, and referral processes, impact patient outcomes in acute stroke cases.
Read the detailed description
The research is a population-based observational cohort study conducted at Assiut University Hospital's Neuropsychiatry Department. It investigates patterns of prehospital stroke care with a focus on patient and caregiver awareness of stroke symptoms, the type of first medical contact, transport modes, referral pathways, and emergency medical service response. The study aims to understand how these prehospital factors influence stroke outcomes, including timely access to treatment, functional recovery, and mortality rates. Standardized tools, structured questionnaires, EMS records, and hospital medical data will be used to collect comprehensive information.
- Conditions
- Prehospital Stroke Care
- Keywords
- Prehospital Stroke Care, Patient Outcome:
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| adults who present with acute stroke | The study population consists of adults who present with acute stroke and have sought or received prehospital care within the hospital's catchment area. Participants are adult patients aged 18 years and above with an acute ischemic or hemorrhagic stroke diagnosis confirmed by neuroimaging |
What is being measured
The primary outcome is the main question the study is designed to answer.
Stroke symptom awareness
Assessment of general knowledge and recognition of stroke symptoms and prehospital care pathways will be measured using the Stroke Knowledge Test (SKT), a validated questionnaire.
The SKT consists of 20 multiple-choice questions evaluating recognition of stroke symptoms and knowledge of emergency response. Scores range from 0 to 20, with higher scores indicating greater awareness and better knowledge.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Sep 2025
- Study start1 Oct 2026 (estimated)
- Primary completion30 Oct 2027 (estimated)
- Study completion30 Dec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Prehospital Stroke CareStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 125 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Refat Hamed Khalaf Ahmed, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07198893
- Sponsor's protocol ID
- Prehospital Stroke Care
- Status last verified
- Sep 2025
- First submitted
- 20 Sep 2025
- Last updated
- 30 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Zachrison KS, Nielsen VM, de la Ossa NP, Madsen TE, Cash RE, Crowe RP, Odom EC, Jauch EC, Adeoye OM, Richards CT. Prehospital Stroke Care Part 1: Emergency Medical Services and the Stroke Systems of Care. Stroke. 2023 Apr;54(4):1138-1147. doi: 10.1161/STROKEAHA.122.039586. Epub 2022 Nov 29.
PubMed 36444720
Study at a glance
From the registry record, last updated by the sponsor on 30 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Pattern and Impact of Prehospital Stroke Care on Patient Outcome: A Population-Based Study
- ClinicalTrials.gov ID
- NCT07198893
- Acronym / sponsor ID
- Prehospital Stroke Care
- Conditions
- Prehospital Stroke Care
- Keywords
- Prehospital Stroke Care, Patient Outcome:
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 125 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 1 Oct 2026 (estimated)
- Primary completion
- 30 Oct 2027 (estimated)
- Study completion
- 30 Dec 2027 (estimated)
- First posted
- 30 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study evaluates how prehospital care factors, including stroke awareness, emergency response, transport, and referral processes, impact patient outcomes in acute stroke cases.
Detailed description
The research is a population-based observational cohort study conducted at Assiut University Hospital's Neuropsychiatry Department. It investigates patterns of prehospital stroke care with a focus on patient and caregiver awareness of stroke symptoms, the type of first medical contact, transport modes, referral pathways, and emergency medical service response. The study aims to understand how these prehospital factors influence stroke outcomes, including timely access to treatment, functional recovery, and mortality rates. Standardized tools, structured questionnaires, EMS records, and hospital medical data will be used to collect comprehensive information.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| adults who present with acute stroke | – | –The study population consists of adults who present with acute stroke and have sought or received prehospital care within the hospital's catchment area. Participants are adult patients aged 18 years and above with an acute ischemic or hemorrhagic stroke diagnosis confirmed by neuroimaging |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Participants are adult patients aged 18 years and above with an acute ischemic or hemorrhagic stroke diagnosis confirmed by neuroimaging. All patients must reside within the defined geographical area and have used emergency medical services or presented directly with stroke symptoms. Caregivers will also provide data regarding symptom recognition and decision-making. Patients with stroke mimics, incomplete records, or without consent will be excluded.
Key inclusion criteria (5 listed)
- Adults ≥18 years of age
- Confirmed diagnosis of acute stroke (ischemic/hemorrhagic) verified by CT or MRI
- Residents of the study's defined geographical area
- Patients who experienced stroke and sought prehospital care pathways (EMS or direct hospital presentation)
- Informed consent from the patient or legally authorized representative
Key exclusion criteria (4 listed)
- Patients with transient ischemic attack (TIA) or stroke mimics without confirmed acute stroke diagnosis
- Missing or incomplete data on prehospital care
- Patients unable or unwilling to provide consent without a representative available
- Non-residents or visitors outside the designated geographical area
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Stroke symptom awareness
Time frame: Baseline
Assessment of general knowledge and recognition of stroke symptoms and prehospital care pathways will be measured using the Stroke Knowledge Test (SKT), a validated questionnaire. The SKT consists of 20 multiple-choice questions evaluating recognition of stroke symptoms and knowledge of emergency response. Scores range from 0 to 20, with higher scores indicating greater awareness and better knowledge.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Sep 2025.
- Background: PubMed 36444720Zachrison KS, Nielsen VM, de la Ossa NP, Madsen TE, Cash RE, Crowe RP, Odom EC, Jauch EC, Adeoye OM, Richards CT. Prehospital Stroke Care Part 1: Emergency Medical Services and the Stroke Systems of Care. Stroke. 2023 Apr;54(4):1138-1147. doi: 10.1161/STROKEAHA.122.039586. Epub 2022 Nov 29.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Prehospital Stroke Care, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 30 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Stroke symptom awareness (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07198893, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Sep 2025; AzTrials last refreshed its copy on 8 Nov 2026.