Periodontal DiseasesPerio-OcclusioNCT07199062
Occlusal Load Distribution and Periodontal Status
An observational study of Periodontal Diseases and Periodontal Pocket, run by University of Bari Aldo Moro.
Trial summary
Occlusal forces are unevenly distributed among teeth during mastication, potentially predisposing certain teeth to higher functional loads. Teeth subjected to increased occlusal loading may be at greater risk of periodontal breakdown, especially in patients with pre-existing periodontal disease. Read more about this study
- Who is it for?
- Ages 18 to 75 yearsHealthy volunteers can take part
- Conditions the study is for
- Periodontal Diseases, Periodontal Pocket, Periodontitis
- How many people
- 50 participants
- Where
- No sites listed yet
- Study dates
- 1 Oct 2025to 1 Apr 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: patients with diagnosed periodontitis
Who may be able to join
- Adults (≥18 years).
- Presence of natural dentition, fixed prostheses, or implant-supported fixed prostheses.
- Ability to undergo radiological (OPT) and periodontal examinations.
- Signed informed consent.
Who cannot join
- Patients wearing removable prostheses.
- Severe systemic conditions contraindicating dental treatment.
- Inability to provide informed consent.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
Saverio Capodiferro, Prof. contact
About this study
Official title: Correlation Between Occlusal Load Distribution and Periodontal Status: A Cohort Study
Occlusal forces are unevenly distributed among teeth during mastication, potentially predisposing certain teeth to higher functional loads. Teeth subjected to increased occlusal loading may be at greater risk of periodontal breakdown, especially in patients with pre-existing periodontal disease.
Technological advances, such as mandibular movement recording systems, allow for precise assessment of occlusal contacts and load distribution. However, the relationship between occlusal loading patterns and periodontal status remains insufficiently investigated.
This study aims to evaluate whether teeth exposed to higher masticatory loads show an association with periodontal disease severity.
- Medical subject headings
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Peri-Implantitis
What is being measured
The primary outcome is the main question the study is designed to answer.
To investigate the correlation between occlusal load distribution, recorded by mandibular movement software , and periodontal condition.
Sowftware analysis
Measured: 5 months
Secondary outcomes (1)
2. To evaluate whether teeth with higher functional loads are more frequently associated with periodontal pocketing.
Periodontal Chating
Measured: 5 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Sep 2025
- Study start1 Oct 2025 (estimated)
- Primary completion1 Jan 2026 (estimated)
- Study completion1 Apr 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Periodontal DiseasesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Bari Aldo Moro
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Giuseppe D'Albis, University of Bari Aldo Moro
- Investigators
- Dr. Giuseppe D'Albis, Principal investigator, University of Bari Aldo MoroProf. Saverio Capodiferro, Study director, University of Bari Aldo Moro
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07199062
- Sponsor's protocol ID
- Perio-Uniba
- Acronym
- Perio-Occlusio
- Status last verified
- Sep 2025
- First submitted
- 21 Sep 2025
- Last updated
- 30 Sep 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Correlation Between Occlusal Load Distribution and Periodontal Status: A Cohort Study
- ClinicalTrials.gov ID
- NCT07199062
- Acronym / sponsor ID
- Perio-Occlusio / Perio-Uniba
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- University of Bari Aldo MoroUniversity, hospital or other
- Study start
- 1 Oct 2025 (estimated)
- Primary completion
- 1 Jan 2026 (estimated)
- Study completion
- 1 Apr 2026 (estimated)
- First posted
- 30 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Occlusal forces are unevenly distributed among teeth during mastication, potentially predisposing certain teeth to higher functional loads. Teeth subjected to increased occlusal loading may be at greater risk of periodontal breakdown, especially in patients with pre-existing periodontal disease.
Technological advances, such as mandibular movement recording systems, allow for precise assessment of occlusal contacts and load distribution. However, the relationship between occlusal loading patterns and periodontal status remains insufficiently investigated.
This study aims to evaluate whether teeth exposed to higher masticatory loads show an association with periodontal disease severity.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- patients with diagnosed periodontitis
Key inclusion criteria (4 listed)
- Adults (≥18 years).
- Presence of natural dentition, fixed prostheses, or implant-supported fixed prostheses.
- Ability to undergo radiological (OPT) and periodontal examinations.
- Signed informed consent.
Key exclusion criteria (3 listed)
- Patients wearing removable prostheses.
- Severe systemic conditions contraindicating dental treatment.
- Inability to provide informed consent.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
To investigate the correlation between occlusal load distribution, recorded by mandibular movement software , and periodontal condition.
Time frame: 5 months
Sowftware analysis
1 secondary outcome
2. To evaluate whether teeth with higher functional loads are more frequently associated with periodontal pocketing.
Time frame: 5 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Sep 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Saverio Capodiferro, Prof. contact
Dr. Giuseppe D'Albis principal investigator
University of Bari Aldo Moro
Prof. Saverio Capodiferro study director
University of Bari Aldo Moro
Questions about this trial
What is this clinical trial studying?
An observational study of Periodontal Diseases and Periodontal Pocket, run by University of Bari Aldo Moro.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 30 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Giuseppe D'Albis, Dr. (+393495103642, giuseppe.dalbis@uniba.it), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
To investigate the correlation between occlusal load distribution, recorded by mandibular movement software , and periodontal condition. (time frame: 5 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Sep 2025.