Hearing DisordersTinCovTimeNCT07199972
COVID-Related Tinnitus Timeline
An observational study of Hearing Disorders and COVID-19 Pandemic, run by Faculdade de Medicina de Valenca at 1 site in Brazil.
Trial summary
COVID-19 is a respiratory disease caused by the coronavirus SARS-CoV-2, for which the first cases were reported in China, by December 2019. Previous studies reported cases of tinnitus following COVID infection, most of them mild and with similar characteristics to other forms of tinnitus. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Hearing Disorders, COVID-19 Pandemic
- How many people
- 233 participants
- Where
- 1 siteBrazil
- Study dates
- 1 Feb 2023to 1 Aug 2025
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients who had a previous COVID-19 infection
Who may be able to join
- previous COVID-19 infection
Who cannot join
- < 18 yo
- not willing to give informed consent
Trial locations and contacts
1 site in 1 country.
Brazil1 site
OTOSUL, Otorrinolaringologia Sul-Fluminense
Volta Redonda, Rio de Janeiro, 27260-200
About this study
Official title: Trajectory of COVID-Related Tinnitus Over the Pandemic Timeline
COVID-19 is a respiratory disease caused by the coronavirus SARS-CoV-2, for which the first cases were reported in China, by December 2019. Previous studies reported cases of tinnitus following COVID infection, most of them mild and with similar characteristics to other forms of tinnitus. Our aim is to further explore the relationship between COVID-19 and tinnitus. For this purpose we analyzed people in the city of Volta Redonda, Brazil after a COVID-19 infection. In detail we compared those with new onset tinnitus during or after COVID-19 with those without tinnitus and those with tinnitus onset before the COVID-19 infection. Moreover we analyzed the prevalence of post-COVID tinnitus along the pandemic timeline, from 2020 to 2024.
Read the detailed description
Two-hundred and thirty three patients over 18 years old and previously diagnosed with COVID-19 confirmed by either a RT-PCR, antibodies or antigens test were included. Patients were subdivided in three groups: no tinnitus (NT), tinnitus that already existed before COVID-19 (chronic tinnitus, CT) and tinnitus that arose during or after COVID-19 (post-COVID-19 tinnitus, PCT). Data concerning COVID-19 symptoms, drugs prescribed for COVID-19, tinnitus characteristics, comorbidities and other otological symptoms were collected. Tinnitus assessment included pure tone audiograms, the Tinnitus Handicap Inventory (THI), visual-analog scales (VAS) for loudness and distress as well as the hospital anxiety and depression scale (HADS). Patients with CT were additionally asked whether their tinnitus worsened after their COVID-19 infection.
- Conditions
- Hearing Disorders, COVID-19 Pandemic
- Keywords
- covid-19, tinnitus
- Medical subject headings
- Hearing Disorders, COVID-19, Tinnitus
What is being measured
The primary outcome is the main question the study is designed to answer.
Trajectory of COVID-Related Tinnitus Over the Pandemic Timeline
Post-COVID tinnitus x No tinnitus x chronic tinnitus
Measured: February 2023 - November 2024
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Sep 2025
- Study start1 Feb 2023
- Primary completion30 Nov 2024
- Study completion1 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hearing DisordersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 233 participants (actual)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Faculdade de Medicina de Valenca
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ricardo Rodrigues Figueiredo, Faculdade de Medicina de Valenca
- Investigators
- Norma O Penido, MD,PhD, Study chair, Universidade Federal de São Paulo
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07199972
- Sponsor's protocol ID
- TinCOVID
- Acronym
- TinCovTime
- Status last verified
- Sep 2025
- First submitted
- 28 Sep 2025
- Last updated
- 30 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Trajectory of COVID-Related Tinnitus Over the Pandemic Timeline
- ClinicalTrials.gov ID
- NCT07199972
- Acronym / sponsor ID
- TinCovTime / TinCOVID
- Conditions
- Hearing Disorders, COVID-19 Pandemic
- Keywords
- covid-19, tinnitus
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 233 participants (actual)
- Lead sponsor
- Faculdade de Medicina de ValencaUniversity, hospital or other
- Study start
- 1 Feb 2023 (actual)
- Primary completion
- 30 Nov 2024 (actual)
- Study completion
- 1 Aug 2025 (actual)
- First posted
- 30 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
COVID-19 is a respiratory disease caused by the coronavirus SARS-CoV-2, for which the first cases were reported in China, by December 2019. Previous studies reported cases of tinnitus following COVID infection, most of them mild and with similar characteristics to other forms of tinnitus. Our aim is to further explore the relationship between COVID-19 and tinnitus. For this purpose we analyzed people in the city of Volta Redonda, Brazil after a COVID-19 infection. In detail we compared those with new onset tinnitus during or after COVID-19 with those without tinnitus and those with tinnitus onset before the COVID-19 infection. Moreover we analyzed the prevalence of post-COVID tinnitus along the pandemic timeline, from 2020 to 2024.
Detailed description
Two-hundred and thirty three patients over 18 years old and previously diagnosed with COVID-19 confirmed by either a RT-PCR, antibodies or antigens test were included. Patients were subdivided in three groups: no tinnitus (NT), tinnitus that already existed before COVID-19 (chronic tinnitus, CT) and tinnitus that arose during or after COVID-19 (post-COVID-19 tinnitus, PCT). Data concerning COVID-19 symptoms, drugs prescribed for COVID-19, tinnitus characteristics, comorbidities and other otological symptoms were collected. Tinnitus assessment included pure tone audiograms, the Tinnitus Handicap Inventory (THI), visual-analog scales (VAS) for loudness and distress as well as the hospital anxiety and depression scale (HADS). Patients with CT were additionally asked whether their tinnitus worsened after their COVID-19 infection.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Target follow-up
- 1 Day
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients who had a previous COVID-19 infection
Key inclusion criteria (1 listed)
- previous COVID-19 infection
Key exclusion criteria (2 listed)
- < 18 yo
- not willing to give informed consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Trajectory of COVID-Related Tinnitus Over the Pandemic Timeline
Time frame: February 2023 - November 2024
Post-COVID tinnitus x No tinnitus x chronic tinnitus
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Sep 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Norma O Penido, MD,PhD study chair
Universidade Federal de São Paulo
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Hearing Disorders and COVID-19 Pandemic, run by Faculdade de Medicina de Valenca at 1 site in Brazil.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Brazil. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Trajectory of COVID-Related Tinnitus Over the Pandemic Timeline (time frame: February 2023 - November 2024). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Sep 2025.