Inguinal Hernia UnilateralNCT07200076
Comparison of Mean Duration of Post Operative Analgesia Following QL-2 Block vs QL-3 Block Using Ropivacain 0.25% in Patients Undergoing Unilateral Inguinal Hernia Repair
A study testing Quadratus Lumborum (QL) Block in people with Inguinal Hernia Unilateral, run by Quaid-e-Azam Medical College at 1 site in Pakistan.
Trial summary
To compare the mean dulation of post operative analgesia following QL2 block (posterior quadratus lumborum block) and the QL3 block (transmuscular quadratus lumborum block) using ropivacaine 0.25% in patients undergoing unilateral inguinai hernia repair. Read more about this study
- Who is it for?
- Ages 18 to 50 years
- Conditions the study is for
- Inguinal Hernia Unilateral
- What is being tested?
- Quadratus Lumborum (QL) Block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 64 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Jul 2024to 28 Jan 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age between 18 and 50 years ASA status 1 or 2 Scheduled for unilateral inguinal hernia repair under General Anaesthesia
Who cannot join
- Patient refusal Patients with pre-existing coagulation abnormalities INR more thnn 1.5 Patients with Strangulated hernia Hypersensitivity to local anaestiretics. Local infection at procedure sito.
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Bahawal Victoria Hospital, Bahawalpur
Bahawalpur, Punjab Province, 63100
About this study
To compare the mean dulation of post operative analgesia following QL2 block (posterior quadratus lumborum block) and the QL3 block (transmuscular quadratus lumborum block) using ropivacaine 0.25% in patients undergoing unilateral inguinai hernia repair.
Rationale of the proposed study is to find an optimal approach for quadratus lumborum block (QLB) in the context of local population as no local study has already been carried out for our population. The study seeks to determine which approach provides superior postoperative pain relief and aspires to establish a clear rationale for the application of one technique over the other in local population. By uncovering the strengths and limitations of each approach, the study intends to guide local clinicians in making informed decisions for optimizing postoperative pain management strategies. The outcomes of this study are anticipated to have a substantial impact on clinical practice, potentially leading to improved patient outcomes, reduced opioid consumption, and enhanced patient comfort following inguinal hernia repair surgeries in local settings.
- Conditions
- Inguinal Hernia Unilateral
- Being tested
- Quadratus Lumborum (QL) Block
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Quadratus Lumborum (QL) BlockProcedure or surgery
In the QLB-2 approach, a needle will be inserted in-plane from anterior to posterior, directed towards the posterior QL muscle border, and a 20 ml solution of 0.25% ropivacaine will be injected.
For the QLB-3 approach, the needle will be inserted in-plane from anterior to posterior, traversing the QL muscle's proper fascia to target the plane between the QL and PM muscles, and a 20 ml solution of 0.25% ropivacaine will be injected.
| Study group | Role | What they receive |
|---|---|---|
| QLB-2 (posterior QL block) Group | Active comparator | Not described Receives: Procedure: Quadratus Lumborum (QL) Block |
| QLB-3 (transmuscular QL block) Group | Active comparator | Not described Receives: Procedure: Quadratus Lumborum (QL) Block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in systolic Blood pressure
Measured: Baseline, 30 minutes, 2 hours, 4 hours, 8 hours, 12 hours 24 hours
Mean duration of analgesia
assessed using the Visual Analog Score (VAS) ranging tiom 0-10 (0= no pain, l0= the most severe unbearable pain)
Measured: Baseline, 30 minutes, 2 hours, 4 hours, 8 hours, 12 hours, 24 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Sep 2025
- Study start1 Jul 2024
- Primary completion30 Dec 2024
- Study completion28 Jan 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Inguinal Hernia UnilateralStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 64 participants (actual)
Sponsor and investigators
- Lead sponsor
- Quaid-e-Azam Medical College
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Dr Muhammad Ayaz, Quaid-e-Azam Medical College
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07200076
- Sponsor's protocol ID
- BVH-2025-CT-010
- Status last verified
- Sep 2025
- First submitted
- 22 Sep 2025
- Last updated
- 6 Oct 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Mean Duration of Post Operative Analgesia Following QL-2 Block vs QL-3 Block Using Ropivacain 0.25% in Patients Undergoing Unilateral Inguinal Hernia Repair
- ClinicalTrials.gov ID
- NCT07200076
- Acronym / sponsor ID
- BVH-2025-CT-010
- Conditions
- Inguinal Hernia Unilateral
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 64 participants (actual)
- Lead sponsor
- Quaid-e-Azam Medical CollegeUniversity, hospital or other
- Study start
- 1 Jul 2024 (actual)
- Primary completion
- 30 Dec 2024 (actual)
- Study completion
- 28 Jan 2025 (actual)
- First posted
- 30 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To compare the mean dulation of post operative analgesia following QL2 block (posterior quadratus lumborum block) and the QL3 block (transmuscular quadratus lumborum block) using ropivacaine 0.25% in patients undergoing unilateral inguinai hernia repair.
Rationale of the proposed study is to find an optimal approach for quadratus lumborum block (QLB) in the context of local population as no local study has already been carried out for our population. The study seeks to determine which approach provides superior postoperative pain relief and aspires to establish a clear rationale for the application of one technique over the other in local population. By uncovering the strengths and limitations of each approach, the study intends to guide local clinicians in making informed decisions for optimizing postoperative pain management strategies. The outcomes of this study are anticipated to have a substantial impact on clinical practice, potentially leading to improved patient outcomes, reduced opioid consumption, and enhanced patient comfort following inguinal hernia repair surgeries in local settings.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| QLB-2 (posterior QL block) Group | Active comparator | Procedure: Quadratus Lumborum (QL) Block |
| QLB-3 (transmuscular QL block) Group | Active comparator | Procedure: Quadratus Lumborum (QL) Block |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Age between 18 and 50 years ASA status 1 or 2 Scheduled for unilateral inguinal hernia repair under General Anaesthesia
Key exclusion criteria (1 listed)
- Patient refusal Patients with pre-existing coagulation abnormalities INR more thnn 1.5 Patients with Strangulated hernia Hypersensitivity to local anaestiretics. Local infection at procedure sito.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Quadratus Lumborum (QL) BlockIn the QLB-2 approach, a needle will be inserted in-plane from anterior to posterior, directed towards the posterior QL muscle border, and a 20 ml solution of 0.25% ropivacaine will be injected. For the QLB-3 approach, the needle will be inserted in-plane from anterior to posterior, traversing the QL muscle's proper fascia to target the plane between the QL and PM muscles, and a 20 ml solution of 0.25% ropivacaine will be injected. | Procedure or surgery | QLB-2 (posterior QL block) Group, QLB-3 (transmuscular QL block) Group |
Primary outcome
Change in systolic Blood pressure
Time frame: Baseline, 30 minutes, 2 hours, 4 hours, 8 hours, 12 hours 24 hours
Mean duration of analgesia
Time frame: Baseline, 30 minutes, 2 hours, 4 hours, 8 hours, 12 hours, 24 hours
assessed using the Visual Analog Score (VAS) ranging tiom 0-10 (0= no pain, l0= the most severe unbearable pain)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Oct 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Quadratus Lumborum (QL) Block in people with Inguinal Hernia Unilateral, run by Quaid-e-Azam Medical College at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in systolic Blood pressure (time frame: Baseline, 30 minutes, 2 hours, 4 hours, 8 hours, 12 hours 24 hours). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Oct 2025.