Pain ManagementNCT07200960
ESP vs Retrolaminar Block: A Randomized Trial
A study testing ESPB in people with Pain Management and Opoid Managment, run by Shaukat Khanum Memorial Cancer Hospital & Research Centre at 1 site in Pakistan.
Trial summary
The study aims to compare the efficacy in pain control and total opioid consumption after the use of ESPB and retrolaminar block in patients undergoing major oncological breast surgery.. Read more about this study
- Who is it for?
- Ages 18 to 60 years, women only
- Conditions the study is for
- Pain Management, Opoid Managment
- What is being tested?
- ESPB
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Feb 2022to 1 Oct 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- Women only
- No healthy volunteers
- Adult
Who may be able to join
- Female patients between 18- 60 years ASA 1 and 2
Who cannot join
- Patient refusal Allergic reaction infection emergency case BMI >35
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Shaukat Khanum Memorial Cancer Hospital & Research Centre.
Lahore, Punjab Province
About this study
Official title: Analgesic Efficacy of Erector Spinae Plane Block Versus Retrolaminar Block in Patients Undergoing Major Oncological Breast Surgery: a Randomized Controllled Trial
The study aims to compare the efficacy in pain control and total opioid consumption after the use of ESPB and retrolaminar block in patients undergoing major oncological breast surgery..
Read the detailed description
The study aims to compare the efficacy in pain control and total opioid consumption after the use of ESPB and retrolaminar block in patients undergoing major oncological breast surgery..
- Conditions
- Pain Management, Opoid Managment
- Being tested
- ESPB
- Medical subject headings
- Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ESPBProcedure or surgery
Also called Retrolaminar Block
Patient receiving ESPB for major oncological breast surgery Patient receiving Retrolaminar Block for major oncological breast surgery
| Study group | Role | What they receive |
|---|---|---|
| Patient receiving ESPB for major oncological breast surgery | Experimental | Patient receiving ESPB for major oncological breast surgery Receives: Procedure: ESPB |
| Patient receiving Retrolaminar block for major oncological breast surgery | Experimental | Patient receiving ESPB for major oncological breast surgery Receives: Procedure: ESPB |
What is being measured
The primary outcome is the main question the study is designed to answer.
Comparison of pain score of patients receiving ESPB and retrolaminar block
Numeric rating scale score
Measured: 2hours post surgery
Secondary outcomes (1)
Comparison of total opioid consumption in 24 hours of patients receiving ESPB and retrolaminar block
total consumption of opioids in MG
Measured: 24 hours post surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Oct 2025
- Study start1 Feb 2022
- Primary completion1 Sep 2024
- Study completion1 Oct 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pain ManagementStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 90 participants (actual)
Sponsor and investigators
- Lead sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07200960
- Sponsor's protocol ID
- IRB-23-02
- Status last verified
- Jan 2026
- First submitted
- 29 Sep 2025
- Last updated
- 8 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Analgesic Efficacy of Erector Spinae Plane Block Versus Retrolaminar Block in Patients Undergoing Major Oncological Breast Surgery: a Randomized Controllled Trial
- ClinicalTrials.gov ID
- NCT07200960
- Acronym / sponsor ID
- IRB-23-02
- Conditions
- Pain Management, Opoid Managment
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 90 participants (actual)
- Lead sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research CentreUniversity, hospital or other
- Study start
- 1 Feb 2022 (actual)
- Primary completion
- 1 Sep 2024 (actual)
- Study completion
- 1 Oct 2024 (actual)
- First posted
- 1 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The study aims to compare the efficacy in pain control and total opioid consumption after the use of ESPB and retrolaminar block in patients undergoing major oncological breast surgery..
Detailed description
The study aims to compare the efficacy in pain control and total opioid consumption after the use of ESPB and retrolaminar block in patients undergoing major oncological breast surgery..
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Patient receiving ESPB for major oncological breast surgery | Experimental | Procedure: ESPBPatient receiving ESPB for major oncological breast surgery |
| Patient receiving Retrolaminar block for major oncological breast surgery | Experimental | Procedure: ESPBPatient receiving ESPB for major oncological breast surgery |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Female patients between 18- 60 years ASA 1 and 2
Key exclusion criteria (1 listed)
- Patient refusal Allergic reaction infection emergency case BMI >35
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ESPBAlso: Retrolaminar BlockPatient receiving ESPB for major oncological breast surgery Patient receiving Retrolaminar Block for major oncological breast surgery | Procedure or surgery | Patient receiving ESPB for major oncological breast surgery, Patient receiving Retrolaminar block for major oncological breast surgery |
Primary outcome
Comparison of pain score of patients receiving ESPB and retrolaminar block
Time frame: 2hours post surgery
Numeric rating scale score
1 secondary outcome
Comparison of total opioid consumption in 24 hours of patients receiving ESPB and retrolaminar block
Time frame: 24 hours post surgery
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jan 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ESPB in people with Pain Management and Opoid Managment, run by Shaukat Khanum Memorial Cancer Hospital & Research Centre at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Comparison of pain score of patients receiving ESPB and retrolaminar block (time frame: 2hours post surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jan 2026.