Osteo Arthritis Knee and HipPARTICIPATENCT07202286
Comparing Physician and Artificial Intelligence Chatbot Responses to Frequently Asked Questions From Osteoarthritis Patients
An observational study of Osteo Arthritis Knee and Hip and Artificial Intelligence (AI), run by Canisius-Wilhelmina Hospital at 1 site in Netherlands.
Trial summary
This study aimed to compare the patient acceptability (preference, length, and difficulty) and accuracy of Chat-Generative Pre-Trained Transformer (ChatGPT) responses to questions from people with osteoarthritis (OA) with physician responses. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Osteo Arthritis Knee and Hip, Artificial Intelligence (AI), Acceptability
- How many people
- 286 participants
- Where
- 1 siteNetherlands
- Study dates
- 22 May 2024to 5 Jun 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: There were two groups of participants: 1) a panel of people with OA evaluating the preference, length, and difficulty, and 2) a panel of experts in the field of OA evaluating the accuracy of the responses
Who may be able to join
- all individuals visiting the Department of Orthopedics in the Canisius Wilhelmina Hospital, a district general hospital in Nijmegen, The Netherlands, diagnosed with knee or hip OA between March 2023 and March 2024
Who cannot join
- partly completion of the questionnaire
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparing Physician and Artificial Intelligence Chatbot Responses to Frequently Asked Questions From Osteoarthritis Patients: a Prospective Cross-sectional Study
This study aimed to compare the patient acceptability (preference, length, and difficulty) and accuracy of Chat-Generative Pre-Trained Transformer (ChatGPT) responses to questions from people with osteoarthritis (OA) with physician responses.
Read the detailed description
This was a cross-sectional study where participants were invited by e-mail to participate in the questionnaire to compare Chatbot responses to physician responses.
- Conditions
- Osteo Arthritis Knee and Hip, Artificial Intelligence (AI), Acceptability, Accuracy, Chatbot
- Keywords
- chatGPT, Osteoarthritis, Acceptability, Accuracy, Artificial Intelligence, Cross-sectional
- Medical subject headings
- Osteoarthritis
What is being measured
The primary outcome is the main question the study is designed to answer.
Preferred response
Binary outcome, chatbot or physician response. This was an average based on the preferences on the 7 FAQs.
Measured: From invitation until the end of the study at two weeks
Secondary outcomes (3)
Rating of length
Rating of both responses (chatbot and physician response) included 'too short', 'good', and 'too long'.
Measured: From invitation until the end of the study at two weeks
Rating of difficulty
Rating of difficulty included 'too easy', 'good', and 'too difficult' for both responses.
Measured: From invitation until the end of the study at two weeks
Accuracy
Accuracy of the responses included the options 'Completely incorrect,' 'partly incorrect, ' 'approximately equally correct and incorrect,' 'mostly correct,' 'completely correct'.
Measured: From invitation until the end of the study at two weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Oct 2025
- Study start22 May 2024
- Primary completion5 Jun 2024
- Study completion5 Jun 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Osteo Arthritis Knee and HipStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 286 participants (actual)
Sponsor and investigators
- Lead sponsor
- Canisius-Wilhelmina Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07202286
- Sponsor's protocol ID
- 075-2023
- Acronym
- PARTICIPATE
- Status last verified
- Oct 2025
- First submitted
- 30 Sep 2025
- Last updated
- 6 Oct 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: The dataset supporting the conclusions of this study is available from the corresponding author upon reasonable request.
Study at a glance
From the registry record, last updated by the sponsor on 6 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparing Physician and Artificial Intelligence Chatbot Responses to Frequently Asked Questions From Osteoarthritis Patients: a Prospective Cross-sectional Study
- ClinicalTrials.gov ID
- NCT07202286
- Acronym / sponsor ID
- PARTICIPATE / 075-2023
- Conditions
- Osteo Arthritis Knee and Hip, Artificial Intelligence (AI), Acceptability, Accuracy, Chatbot
- Keywords
- chatGPT, Osteoarthritis, Acceptability, Accuracy, Artificial Intelligence, Cross-sectional
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 286 participants (actual)
- Lead sponsor
- Canisius-Wilhelmina HospitalUniversity, hospital or other
- Study start
- 22 May 2024 (actual)
- Primary completion
- 5 Jun 2024 (actual)
- Study completion
- 5 Jun 2024 (actual)
- First posted
- 1 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aimed to compare the patient acceptability (preference, length, and difficulty) and accuracy of Chat-Generative Pre-Trained Transformer (ChatGPT) responses to questions from people with osteoarthritis (OA) with physician responses.
Detailed description
This was a cross-sectional study where participants were invited by e-mail to participate in the questionnaire to compare Chatbot responses to physician responses.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- There were two groups of participants: 1) a panel of people with OA evaluating the preference, length, and difficulty, and 2) a panel of experts in the field of OA evaluating the accuracy of the responses
Key inclusion criteria (1 listed)
- all individuals visiting the Department of Orthopedics in the Canisius Wilhelmina Hospital, a district general hospital in Nijmegen, The Netherlands, diagnosed with knee or hip OA between March 2023 and March 2024
Key exclusion criteria (1 listed)
- partly completion of the questionnaire
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Preferred response
Time frame: From invitation until the end of the study at two weeks
Binary outcome, chatbot or physician response. This was an average based on the preferences on the 7 FAQs.
3 secondary outcomes
Rating of length
Time frame: From invitation until the end of the study at two weeks
Rating of difficulty
Time frame: From invitation until the end of the study at two weeks
Accuracy
Time frame: From invitation until the end of the study at two weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Oct 2025.
- Individual participant dataSharing planned: Undecided. The dataset supporting the conclusions of this study is available from the corresponding author upon reasonable request.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Osteo Arthritis Knee and Hip and Artificial Intelligence (AI), run by Canisius-Wilhelmina Hospital at 1 site in Netherlands.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Netherlands. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Preferred response (time frame: From invitation until the end of the study at two weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Oct 2025.