Prostate CancerNCT07205783
Open Radical Prostatectomy Versus Curative Radiotherapy for Treatment of Organ Confined Prostate Cancer (Retrospective Comparative Study)
A study testing open radical prostatectomy and curative radiotherapy in people with Prostate Cancer, run by Sohag University at 1 site in Egypt.
Trial summary
In the last few decades not only the diagnosis but also the treatment options for prostate cancer have changed significantly. During this time the surgical procedure of open radical prostatectomy was substantially modified(1,2) and is nowadays considered a safe procedure providing high cancer control rates with low… Read more about this study
- Who is it for?
- Ages 40 years and older, men only
- Conditions the study is for
- Prostate Cancer
- What is being tested?
- open radical prostatectomy and curative radiotherapy
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 14 Sep 2022to 1 Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 years and older
- Men only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Cancer prostate: confirmed by prostate biopsy Cancer stage: T2,T3
Who cannot join
- coagulopathy. Pulmonary diseases metastatic tumor
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
In the last few decades not only the diagnosis but also the treatment options for prostate cancer have changed significantly. During this time the surgical procedure of open radical prostatectomy was substantially modified(1,2) and is nowadays considered a safe procedure providing high cancer control rates with low morbidity.(3) The main goal of radical prostatectomy regardless of the approach remains the eradication of cancer while preserving pelvic organ function,whenever possible.(4)
- Conditions
- Prostate Cancer
- Being tested
- open radical prostatectomy, curative radiotherapy
- Keywords
- open radical prostatectomy prostate cancer
- Medical subject headings
- Prostatic Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
open radical prostatectomyProcedure or surgery
open surgery to remove prostate gland and the tumor
curative radiotherapyRadiation
radiotherapy to the prostate gland and the tumor
| Study group | Role | What they receive |
|---|---|---|
| radical prostatectomy | Active comparator | Not described Receives: Procedure: open radical prostatectomy |
| curative radiotherapy | Active comparator | Not described Receives: Radiation: curative radiotherapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
tumor control
percentage of tumor recurrence
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Oct 2025
- Study start14 Sep 2022
- Primary completion14 Sep 2026 (estimated)
- Study completion1 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Prostate CancerStudies of the same condition, open and under way.
- More trials run by Sohag UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sohag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Khalaf Elsayed, Sohag University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07205783
- Sponsor's protocol ID
- Soh-Med-25-9-2MD
- Status last verified
- Apr 2026
- First submitted
- 26 Sep 2025
- Last updated
- 7 Apr 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Open Radical Prostatectomy Versus Curative Radiotherapy for Treatment of Organ Confined Prostate Cancer (Retrospective Comparative Study)
- ClinicalTrials.gov ID
- NCT07205783
- Acronym / sponsor ID
- Soh-Med-25-9-2MD
- Conditions
- Prostate Cancer
- Keywords
- open radical prostatectomy prostate cancer
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Sohag UniversityUniversity, hospital or other
- Study start
- 14 Sep 2022 (actual)
- Primary completion
- 14 Sep 2026 (estimated)
- Study completion
- 1 Jan 2027 (estimated)
- First posted
- 3 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In the last few decades not only the diagnosis but also the treatment options for prostate cancer have changed significantly. During this time the surgical procedure of open radical prostatectomy was substantially modified(1,2) and is nowadays considered a safe procedure providing high cancer control rates with low morbidity.(3) The main goal of radical prostatectomy regardless of the approach remains the eradication of cancer while preserving pelvic organ function,whenever possible.(4)
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| radical prostatectomy | Active comparator | Procedure: open radical prostatectomy |
| curative radiotherapy | Active comparator | Radiation: curative radiotherapy |
Who may qualify
- Ages
- 40 years and older
- Sex
- Male only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Cancer prostate: confirmed by prostate biopsy Cancer stage: T2,T3
Key exclusion criteria (1 listed)
- coagulopathy. Pulmonary diseases metastatic tumor
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| open radical prostatectomyopen surgery to remove prostate gland and the tumor | Procedure or surgery | radical prostatectomy |
| curative radiotherapyradiotherapy to the prostate gland and the tumor | Radiation | curative radiotherapy |
Primary outcome
tumor control
Time frame: 6 months
percentage of tumor recurrence
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Apr 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing open radical prostatectomy and curative radiotherapy in people with Prostate Cancer, run by Sohag University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 7 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
tumor control (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Apr 2026.