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Cohort StudyNCT07207863

Tianshan Community Cohort Establishment and Follow-up

An observational study of Cohort Study and Natural Population, run by People's Hospital of Xinjiang Uygur Autonomous Region at 1 site in China.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

This population-based cohort study on disease prevention and health promotion was established in northwest China, leveraging data from routine annual health examinations. Initiated in January 2016, the cohort enrolled nearly all residents aged 18 years and older who were registered at community healthcare centers. Read more about this study

Who is it for?
Ages 18 years and olderHealthy volunteers can take part
How many people
1,000,000 participants
Where
1 siteChina
Study dates
1 Jan 2016to 31 Dec 2035
Phase
Observational
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Study population: Eligible residents from routine annual health examinations.

Who may be able to join

  • Residents >=18y
  • Permanent residents or individuals who have lived in the region for more than 5 years and are enrolled in local social security medical insurance
  • Residents without severe physical disability and capable of normal communication
  • Residents whose diseases and deaths are monitored and managed by the local health authorities
  • Residents who voluntarily participate and provide written informed consent

Who cannot join

  • Temporary residents or floating population
  • Residents with severe health conditions that prevent participation in the study
  • Residents who are unwilling to undergo follow-up assessments for the study

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Qian Zhao, Dr. contact

+86-13899993630

tina0627@126.com

China1 site, 1 recruiting

  • People's Hospital of Xinjiang Uygur Autonomous Region

    Ürümqi, Xinjiang, 830001

    Qian Zhao, Dr., +8613899993630, tina0627@126.com

    Yining Yang, Prof.

    Recruiting

Other trials in China

About this study

Official title: The Cardiac and Panvascular Medicine Diagnosis and Treatment Center, People's Hospital of Xinjiang Uygur Autonomous Region,

This population-based cohort study on disease prevention and health promotion was established in northwest China, leveraging data from routine annual health examinations. Initiated in January 2016, the cohort enrolled nearly all residents aged 18 years and older who were registered at community healthcare centers. The program was developed to provide a comprehensive framework for disease prevention and community health promotion, with the aim of producing population-based evidence across a broad spectrum of diseases in the general population. At baseline, data were collected on participant demographics, medical and family histories, disability status, living environment, and blood biochemical parameters. Follow-up information is primarily obtained through chronic disease management programs, annual health examinations, and electrical health records. Cause-specific mortality is ascertained from local death registration systems. Biological specimens, questionnaire data, and electrical health records are systematically archived in the Biobank and Big Data Center of the People's Hospital of Xinjiang Uygur Autonomous Region.

Read the detailed description

This research is conducted through population-based health examinations among residents in northwest China. By providing annual health assessments, structured health education, and community-based health promotion activities, the study aims to enhance health awareness, identify determinants of disease, implement targeted interventions to improve lifestyle behaviors, reduce modifiable risk factors, and promote overall community health.

The cohort integrates data from multiple sources- including health assessments, electronic health records, mortality registries, statistical yearbooks, and environmental datasets- encompassing a wide range of health-related information, such as demographics, lifestyle factors, family and personal medical histories, living conditions, enrollment in national public health services, physical examinations, laboratory tests, diagnostic assessments, disease outcomes, and cause-specific mortality. Event-driven follow-up data are obtained from 163 hospitals and 63 Traditional Chinese Medicine hospitals, covering all secondary and tertiary-level hospitals in the region. Inpatient data are systematically documented by qualified medical personnel and entered into an electronic health information system. All disease diagnoses are coded according to the 10th Revision of the International Classification of Diseases (ICD-10). Mortality data, including the timing and specific cause of death, are primarily obtained through local death registration systems.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Mortality

    All-cause and cause-specific mortality during follow-up

    Measured: 20 years

  2. Cardiovascular diseases

    Incident disease during follow-up

    Measured: 20 years

  3. Digestive diseases

    Incident disease during follow-up

    Measured: 20 years

  4. Endocrine diseases

    Incident disease during follow-up

    Measured: 20 years

  5. Infections diseases

    Incident disease during follow-up

    Measured: 20 years

  6. Benign neoplasm or Carcinoma in situ

    Incident disease during follow-up

    Measured: 20 years

  7. Cancers

    Incident disease during follow-up

    Measured: 20 years

  8. Genitourinary diseases

    Incident disease during follow-up

    Measured: 20 years

  9. Haematological or immunological diseases

    Incident disease during follow-up

    Measured: 20 years

  10. Musculoskeletal diseases

    Incident disease during follow-up

    Measured: 20 years

  11. Neurological diseases

    Incident disease during follow-up

    Measured: 20 years

  12. Psychiatric diseases

    Incident disease during follow-up

    Measured: 20 years

  13. Respiratory diseases

    Incident disease during follow-up

    Measured: 20 years

  14. Ocular diseases

    Incident disease during follow-up

    Measured: 20 years

  15. Dermatological diseases

    Incident disease during follow-up

    Measured: 20 years

  16. Ear and mastoid disorders

    Incident disease during follow-up

    Measured: 20 years

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted6 Oct 2025
  2. Study start1 Jan 2016
  3. Primary completion31 Dec 2035 (estimated)
  4. Study completion31 Dec 2035 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
1,000,000 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07207863
Sponsor's protocol ID
Tianshan2025
Status last verified
Sep 2025
First submitted
27 Sep 2025
Last updated
6 Oct 2025
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

An observational study of Cohort Study and Natural Population, run by People's Hospital of Xinjiang Uygur Autonomous Region at 1 site in China.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 6 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Qian Zhao, Dr. (+86-13899993630, tina0627@126.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Mortality (time frame: 20 years). The study lists 16 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07207863.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Oct 2025.

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