Alveolar Bone LossNCT07209618
Horizontal Ridge Augmentation With Simultaneous Implant Placement Using Autogenous Ramus Grafts
An observational study of Alveolar Bone Loss and Tooth Loss / Rehabilitation, run by Akdeniz University at 1 site in Turkey (Türkiye).
Trial summary
This retrospective observational study evaluated the clinical outcomes of simultaneous implant placement with horizontal ridge augmentation using autogenous mandibular ramus block grafts. Sixteen patients were treated between January 2018 and March 2025. Read more about this study
- Who is it for?
- Ages 18 to 70 years
- Conditions the study is for
- Alveolar Bone Loss, Tooth Loss / Rehabilitation
- What is being tested?
- utogenous mandibular ramus block grafting with simultaneous dental implant placement and Autogenous mandibular ramus block graft with simultaneous implant placement
- Type of treatment
- Surgery or procedure
- How many people
- 16 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jan 2018to 31 Jul 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Sixteen patients (9 females, 7 males; mean age 41.4 years, range 21-61 years) with horizontal alveolar ridge deficiencies were treated at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Akdeniz University, between January 2018 and March 2025. All patients underwent horizontal ridge augmentation with autogenous mandibular ramus block grafts in conjunction with simultaneous implant placement.
Who may be able to join
- Patients ≥18 years of age
- ASA I or II status
- Presence of horizontal alveolar ridge deficiency requiring augmentation for implant placement
- Treated with autogenous mandibular ramus block grafts and simultaneous implant placement
- Provided informed consent for surgical and prosthetic procedures, and use of clinical and radiological data
Who cannot join
- Systemic conditions interfering with dental implant treatment (e.g., uncontrolled diabetes, metabolic bone disease)
- Incomplete clinical or radiological records
- Patients with contraindications for oral surgical procedures
- Patients unwilling to provide informed consent
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Rehabilitation of Alveolar Horizontal Bone Deficiencies Using Autogenous Onlay Bone Grafting With Simultaneous Implant Placement: A Novel Approach
This retrospective observational study evaluated the clinical outcomes of simultaneous implant placement with horizontal ridge augmentation using autogenous mandibular ramus block grafts. Sixteen patients were treated between January 2018 and March 2025. Clinical and radiological data were analyzed to assess implant survival, osseointegration, and graft incorporation.
Read the detailed description
Horizontal alveolar bone deficiency is a significant challenge in implant rehabilitation. Traditional staged augmentation techniques prolong treatment time and increase morbidity. This study introduces a novel approach in which autogenous mandibular ramus block grafts were used to reconstruct buccal walls simultaneously with implant placement. Sixteen patients received 23 implants. Outcomes included implant survival, osseointegration success, bone healing, and complications during a mean follow-up of 30.6 months.
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation
- Being tested
- utogenous mandibular ramus block grafting with simultaneous dental implant placement, Autogenous mandibular ramus block graft with simultaneous implant placement
- Medical subject headings
- Alveolar Bone Loss, Tooth Loss
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
utogenous mandibular ramus block grafting with simultaneous dental implant placementProcedure or surgery
Horizontal alveolar ridge augmentation performed using autogenous block grafts harvested from the mandibular ramus. The graft was fixed to reconstruct the buccal wall, followed by immediate placement of dental implants in the same surgical session. Prosthetic loading was initiated 4 months postoperatively.
Autogenous mandibular ramus block graft with simultaneous implant placementProcedure or surgery
Horizontal alveolar ridge augmentation performed using autogenous block grafts harvested from the mandibular ramus. The graft was fixed to reconstruct the buccal wall, followed by immediate placement of dental implants in the same surgical session. Prosthetic loading was initiated 4 months postoperatively.
| Study group | Role | What they receive |
|---|---|---|
| Simultaneous implant + ramus graft group | Not described Receives: Procedure: utogenous mandibular ramus block grafting with simultaneous dental implant placement; Procedure: Autogenous mandibular ramus block graft with simultaneous implant placement |
What is being measured
The primary outcome is the main question the study is designed to answer.
implant survival rate
Measured: 4 months post-surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Oct 2025
- Study start1 Jan 2018
- Primary completion31 Jul 2025
- Study completion31 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Alveolar Bone LossStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 16 participants (actual)
Sponsor and investigators
- Lead sponsor
- Akdeniz University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Oznur Ozalp, Akdeniz University
- Investigators
- Ozalp, Principal investigator, Akdeniz University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07209618
- Sponsor's protocol ID
- AKDENIZ-RAMUS-2018-TBAEK-415
- Status last verified
- Sep 2025
- First submitted
- 29 Sep 2025
- Last updated
- 7 Oct 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 7 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Rehabilitation of Alveolar Horizontal Bone Deficiencies Using Autogenous Onlay Bone Grafting With Simultaneous Implant Placement: A Novel Approach
- ClinicalTrials.gov ID
- NCT07209618
- Acronym / sponsor ID
- AKDENIZ-RAMUS-2018-TBAEK-415
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 16 participants (actual)
- Lead sponsor
- Akdeniz UniversityUniversity, hospital or other
- Study start
- 1 Jan 2018 (actual)
- Primary completion
- 31 Jul 2025 (actual)
- Study completion
- 31 Jul 2025 (actual)
- First posted
- 7 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This retrospective observational study evaluated the clinical outcomes of simultaneous implant placement with horizontal ridge augmentation using autogenous mandibular ramus block grafts. Sixteen patients were treated between January 2018 and March 2025. Clinical and radiological data were analyzed to assess implant survival, osseointegration, and graft incorporation.
Detailed description
Horizontal alveolar bone deficiency is a significant challenge in implant rehabilitation. Traditional staged augmentation techniques prolong treatment time and increase morbidity. This study introduces a novel approach in which autogenous mandibular ramus block grafts were used to reconstruct buccal walls simultaneously with implant placement. Sixteen patients received 23 implants. Outcomes included implant survival, osseointegration success, bone healing, and complications during a mean follow-up of 30.6 months.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Simultaneous implant + ramus graft group | – | Procedure: utogenous mandibular ramus block grafting with simultaneous dental implant placement, Procedure: Autogenous mandibular ramus block graft with simultaneous implant placement |
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Sixteen patients (9 females, 7 males; mean age 41.4 years, range 21-61 years) with horizontal alveolar ridge deficiencies were treated at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Akdeniz University, between January 2018 and March 2025. All patients underwent horizontal ridge augmentation with autogenous mandibular ramus block grafts in conjunction with simultaneous implant placement.
Key inclusion criteria (5 listed)
- Patients ≥18 years of age
- ASA I or II status
- Presence of horizontal alveolar ridge deficiency requiring augmentation for implant placement
- Treated with autogenous mandibular ramus block grafts and simultaneous implant placement
- Provided informed consent for surgical and prosthetic procedures, and use of clinical and radiological data
Key exclusion criteria (4 listed)
- Systemic conditions interfering with dental implant treatment (e.g., uncontrolled diabetes, metabolic bone disease)
- Incomplete clinical or radiological records
- Patients with contraindications for oral surgical procedures
- Patients unwilling to provide informed consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| utogenous mandibular ramus block grafting with simultaneous dental implant placementHorizontal alveolar ridge augmentation performed using autogenous block grafts harvested from the mandibular ramus. The graft was fixed to reconstruct the buccal wall, followed by immediate placement of dental implants in the same surgical session. Prosthetic loading was initiated 4 months postoperatively. | Procedure or surgery | Simultaneous implant + ramus graft group |
| Autogenous mandibular ramus block graft with simultaneous implant placementHorizontal alveolar ridge augmentation performed using autogenous block grafts harvested from the mandibular ramus. The graft was fixed to reconstruct the buccal wall, followed by immediate placement of dental implants in the same surgical session. Prosthetic loading was initiated 4 months postoperatively. | Procedure or surgery | Simultaneous implant + ramus graft group |
Primary outcome
implant survival rate
Time frame: 4 months post-surgery
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Oct 2025.
- Individual participant dataSharing planned: Undecided
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Melatonin Effect on Immediate Dental Implants in the Posterior Mandible
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ozalp principal investigator
Akdeniz University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Alveolar Bone Loss and Tooth Loss / Rehabilitation, run by Akdeniz University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 7 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
implant survival rate (time frame: 4 months post-surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Oct 2025.