Hypertension (HTN)V-EDUCATENCT07210073
Video Education to Improve Blood Pressure Control in Patients With Ischemic Heart Disease and Hypertension (V-EDUCATE)
A study testing Video Education in people with Hypertension (HTN) and Ischemic Heart Disease, run by Keimyung University Dongsan Medical Center at 1 site in South Korea.
Trial summary
We investigated whether video-based education using deepfake technology could improve blood pressure measurement adherence and medication adherence in patients with ischemic heart disease accompanied by hypertension. Read more about this study
- Who is it for?
- Ages 19 years and older
- Conditions the study is for
- Hypertension (HTN), Ischemic Heart Disease
- What is being tested?
- Video Education
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 218 participants
- Where
- 1 siteSouth Korea
- Study dates
- 27 May 2024to 30 Mar 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 19 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults aged 19 years or older, both male and female, with a history of hypertension or who have taken antihypertensive medication at least once, satisfying one or more of the following ischemic heart disease conditions (PCI, CABG, CAD >50% by CCT or CAG), or patients with a history of hypertension or currently taking antihypertensive medication.
- Individuals who have voluntarily provided written consent to participate in this clinical trial.
Who cannot join
- SBP < 90 mmHg or DBP < 50 mmHg
- Individuals intolerant to all antihypertensive medications
- Patients with heart failure due to other causes, Pregnant women, those suspected of being pregnant, or those who are breastfeeding
- Patients whom the investigator deems legally or mentally unfit to participate in the clinical trial
- Patients who have participated in another clinical study involving investigational drugs within 4 weeks prior to screening.
Trial locations and contacts
1 site in 1 country.
South Korea1 site
Keimyung University Dongsan Hospital
Daegu, Daegu, 42601
About this study
Official title: Video Assisted Education to Improve Blood Pressure Control in Ischemic Heart Disease Patients With Hypertension: Randomized Controlled Trial
We investigated whether video-based education using deepfake technology could improve blood pressure measurement adherence and medication adherence in patients with ischemic heart disease accompanied by hypertension.
Read the detailed description
Hypertension is a major risk factor for recurrent cardiovascular events in patients with ischemic heart disease, yet adherence to home blood pressure monitoring and prescribed medications remains suboptimal. Personalized and engaging educational strategies may help to improve adherence behaviors in this population.
This randomized controlled trial investigates the effectiveness of a video-based educational program, developed with deepfake technology, to deliver individualized health information. Participants are randomly assigned to either the intervention group, which receives the video education in addition to usual care, or the control group, which receives usual care alone.
The primary outcomes are adherence to home blood pressure monitoring and medication adherence after one month. Secondary outcomes include changes in office and home blood pressure, as well as 24-hour ambulatory blood pressure monitoring. The results of this study may provide evidence for scalable, technology-assisted strategies to enhance adherence and improve blood pressure control in high-risk cardiovascular patients.
- Conditions
- Hypertension (HTN), Ischemic Heart Disease
- Being tested
- Video Education, Control
- Medical subject headings
- Hypertension, Myocardial Ischemia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Video EducationBehavioural
Videos were created using deepfake technology, utilizing AI to replicate the voice of the patients' primary physician.
ControlOther
Standard treatment
| Study group | Role | What they receive |
|---|---|---|
| Video education | Experimental | Participants receive personalized video-based education developed using deepfake technology to replicate the patient's primary physician's voice, in addition to usual care. Receives: Behavioral: Video Education |
| Standard Care | Active comparator | Participants receive standard treatment for ischemic heart disease and hypertension, without additional video-based education. Receives: Other: Control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Adherence to Home Blood Pressure Monitoring (HBPM)
Proportion of days during the 30-day follow-up period in which participants recorded four BP measurements per day (two in the morning, two in the evening) using a validated home BP device (InBody BP170).
Measured: 4 weeks
Medication Adherence Assessed by Pill Count
Proportion of prescribed antihypertensive medication doses taken during the 30-day follow-up period, assessed by pill counts at the follow-up visit.
Measured: 4 weeks
Secondary outcomes (6)
Change in Office Systolic Blood Pressure From Baseline to 4 Weeks
Mean change in systolic blood pressure (SBP) measured in clinic using a standardized sphygmomanometer at baseline and 4 weeks.
Measured: 4 weeks
Change in Office Diastolic Blood Pressure From Baseline to 4 Weeks
Mean change in diastolic blood pressure (DBP) measured in clinic using a standardized sphygmomanometer at baseline and 4 weeks.
Measured: 4 weeks
Difference in Mean Systolic Blood Pressure Between Home BP Monitoring and 24-Hour Ambulatory Monitoring
Difference between mean SBP values obtained from home BP monitoring (HBPM) and 24-hour ambulatory BP monitoring (ABPM).
Measured: 4 weeks
Difference in Mean Diastolic Blood Pressure Between Home BP Monitoring and 24-Hour Ambulatory Monitoring
Difference between mean DBP values obtained from HBPM and ABPM.
Measured: 4 weeks
Number of Antihypertensive Medications Prescribed Per Participant
Total number of prescribed antihypertensive medications per participant at baseline and at 4 weeks.
Measured: 4 weeks
Distribution of Antihypertensive Medication Classes Used
Proportion of participants prescribed each class of antihypertensive medication (RAAS inhibitors, beta-blockers, calcium channel blockers, diuretics, etc.) at baseline and 4 weeks.
Measured: 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Oct 2025
- Study start27 May 2024
- Primary completion4 Feb 2025
- Study completion30 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hypertension (HTN)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 218 participants (actual)
Sponsor and investigators
- Lead sponsor
- Keimyung University Dongsan Medical Center
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07210073
- Sponsor's protocol ID
- 2024-02-053
- Acronym
- V-EDUCATE
- Status last verified
- Feb 2025
- First submitted
- 14 Sep 2025
- Last updated
- 7 Oct 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Video Assisted Education to Improve Blood Pressure Control in Ischemic Heart Disease Patients With Hypertension: Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07210073
- Acronym / sponsor ID
- V-EDUCATE / 2024-02-053
- Conditions
- Hypertension (HTN), Ischemic Heart Disease
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 218 participants (actual)
- Lead sponsor
- Keimyung University Dongsan Medical CenterUniversity, hospital or other
- Study start
- 27 May 2024 (actual)
- Primary completion
- 4 Feb 2025 (actual)
- Study completion
- 30 Mar 2025 (actual)
- First posted
- 7 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
We investigated whether video-based education using deepfake technology could improve blood pressure measurement adherence and medication adherence in patients with ischemic heart disease accompanied by hypertension.
Detailed description
Hypertension is a major risk factor for recurrent cardiovascular events in patients with ischemic heart disease, yet adherence to home blood pressure monitoring and prescribed medications remains suboptimal. Personalized and engaging educational strategies may help to improve adherence behaviors in this population.
This randomized controlled trial investigates the effectiveness of a video-based educational program, developed with deepfake technology, to deliver individualized health information. Participants are randomly assigned to either the intervention group, which receives the video education in addition to usual care, or the control group, which receives usual care alone.
The primary outcomes are adherence to home blood pressure monitoring and medication adherence after one month. Secondary outcomes include changes in office and home blood pressure, as well as 24-hour ambulatory blood pressure monitoring. The results of this study may provide evidence for scalable, technology-assisted strategies to enhance adherence and improve blood pressure control in high-risk cardiovascular patients.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Video education | Experimental | Behavioral: Video EducationParticipants receive personalized video-based education developed using deepfake technology to replicate the patient's primary physician's voice, in addition to usual care. |
| Standard Care | Active comparator | Other: ControlParticipants receive standard treatment for ischemic heart disease and hypertension, without additional video-based education. |
Who may qualify
- Ages
- 19 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Adults aged 19 years or older, both male and female, with a history of hypertension or who have taken antihypertensive medication at least once, satisfying one or more of the following ischemic heart disease conditions (PCI, CABG, CAD >50% by CCT or CAG), or patients with a history of hypertension or currently taking antihypertensive medication.
- Individuals who have voluntarily provided written consent to participate in this clinical trial.
Key exclusion criteria (5 listed)
- SBP < 90 mmHg or DBP < 50 mmHg
- Individuals intolerant to all antihypertensive medications
- Patients with heart failure due to other causes, Pregnant women, those suspected of being pregnant, or those who are breastfeeding
- Patients whom the investigator deems legally or mentally unfit to participate in the clinical trial
- Patients who have participated in another clinical study involving investigational drugs within 4 weeks prior to screening.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Video EducationVideos were created using deepfake technology, utilizing AI to replicate the voice of the patients' primary physician. | Behavioural | Video education |
| ControlStandard treatment | Other | Standard Care |
Primary outcome
Adherence to Home Blood Pressure Monitoring (HBPM)
Time frame: 4 weeks
Proportion of days during the 30-day follow-up period in which participants recorded four BP measurements per day (two in the morning, two in the evening) using a validated home BP device (InBody BP170).
Medication Adherence Assessed by Pill Count
Time frame: 4 weeks
Proportion of prescribed antihypertensive medication doses taken during the 30-day follow-up period, assessed by pill counts at the follow-up visit.
6 secondary outcomes
Change in Office Systolic Blood Pressure From Baseline to 4 Weeks
Time frame: 4 weeks
Change in Office Diastolic Blood Pressure From Baseline to 4 Weeks
Time frame: 4 weeks
Difference in Mean Systolic Blood Pressure Between Home BP Monitoring and 24-Hour Ambulatory Monitoring
Time frame: 4 weeks
Difference in Mean Diastolic Blood Pressure Between Home BP Monitoring and 24-Hour Ambulatory Monitoring
Time frame: 4 weeks
Number of Antihypertensive Medications Prescribed Per Participant
Time frame: 4 weeks
Distribution of Antihypertensive Medication Classes Used
Time frame: 4 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Oct 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Video Education in people with Hypertension (HTN) and Ischemic Heart Disease, run by Keimyung University Dongsan Medical Center at 1 site in South Korea.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 7 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Adherence to Home Blood Pressure Monitoring (HBPM) (time frame: 4 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Oct 2025.