Deviated Nasal Septum and Maxillary SinusitisNCT07210827
Deviated Nasal Septum Effect on Maxillary Sinus Volumes and Development of Maxillary Sinusitis by CT
An observational study of Deviated Nasal Septum and Maxillary Sinusitis, run by Assiut University.
Trial summary
By using CT of the nose and paranasal sinuses, we'll study the effect of nasal septum deviation on maxillary sinus volumes, assess the association between the severity and type of nasal septum deviation and the occurrence of maxillary sinusitis and compare the maxillary sinus volume on the deviated side with that of… Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- Deviated Nasal Septum and Maxillary Sinusitis
- How many people
- 120 participants
- Where
- No sites listed yet
- Study dates
- 1 Oct 2025to Oct 2026
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- Adult, Older adult
Study population: Patients presented to outpatient clinic at Assiut University hospital complaining of nasal symptoms like nasal obstruction, rhinorrhea ,headache, and recurrent sinusitis.
Who may be able to join
- Age ≥18 years.
- Availability of high-resolution CT scans of paranasal Sinuses (axial, coronal, sagittal views).
- Adequate imaging quality allowing sinus volumetry and septal deviation measurement.
- Anatomical landmarks visible: Crista galli, hard palate, choanae, uncinate process/OMC region clearly identifiable to permit NSD measurement and sinus segmentation.
Who cannot join
- Age < 18 years.
- Previous sinonasal or maxillofacial surgery.
- History of facial trauma or fractures affecting the nasal septum or sinus walls.
- Sinonasal tumors, polyps, or large cysts.
- Congenital craniofacial anomalies (e.g., cleft palate).
- head and neck syndromes.
- Cases with systemic diseases affecting growth and development.
- -
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: The Effect of Nasal Septal Deviation on Maxillary Sinus Volumes and Development of Maxillary Sinusitis :A CT Study.
By using CT of the nose and paranasal sinuses, we'll study the effect of nasal septum deviation on maxillary sinus volumes, assess the association between the severity and type of nasal septum deviation and the occurrence of maxillary sinusitis and compare the maxillary sinus volume on the deviated side with that of the contralateral side.
- Medical subject headings
- Maxillary Sinusitis
What is being measured
The primary outcome is the main question the study is designed to answer.
CT based comparison in cases with deviated nasal septum
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Oct 2025
- Study start1 Oct 2025 (estimated)
- Primary completionOct 2026 (estimated)
- Study completionOct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Deviated Nasal Septum and Maxillary SinusitisStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Rana Emad Ali, Assiut University
- Investigators
- Ahmed Abdelaleem, Study chair, Professor at ENT department,Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07210827
- Sponsor's protocol ID
- CT in nasal septal deviation
- Status last verified
- Sep 2025
- First submitted
- 30 Sep 2025
- Last updated
- 7 Oct 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Razavi M, Shams N, Pirasteh SMA. Determining the effects of deviated nasal septum on maxillary sinus volume using cone-beam computed tomography. Immunopathol Persa. 2023;9(1):e34427
Elahi MM, Frenkiel S, Fageeh N. Paraseptal structural changes and chronic sinus disease in relation to the deviated septum. J Otolaryngol. 1997 Aug;26(4):236-40.
PubMed 9263892Serifoglu I, Oz II, Damar M, Buyukuysal MC, Tosun A, Tokgoz O. Relationship between the degree and direction of nasal septum deviation and nasal bone morphology. Head Face Med. 2017 Feb 28;13(1):3. doi: 10.1186/s13005-017-0136-2.
PubMed 28245851