Suicidal IdeationASSISTNCT07211373
Advancing Student Suicide Interventions With Scalable Technologies
A study testing Jaspr and Behavioral support in people with Suicidal Ideation and Suicide Attempt, run by University of Massachusetts, Amherst at 1 site in United States.
Trial summary
Mobile-based applications, such as JasprHealth, can deliver evidence-based skills intended to reduce imminent suicide risk (e.g., reducing means access), improve emotional states (e.g., via distraction and coaching to act opposite to emotions), and reduce feelings of social isolation (e.g., via shared stories), but… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Suicidal Ideation, Suicide Attempt, Self-Harm
- What is being tested?
- Jaspr and Behavioral support
- Type of treatment
- Pill or oral medicine, Medical device, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteUnited States
- Study dates
- 8 Oct 2025to 30 Jun 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Recent suicidal thoughts or behavior (i.e., past 2-week suicidal ideation or past 6-month suicidal behaviors)
- Current UMass Amherst or University of Wisconsin Madison undergraduate student
- 18 years of age or older
- Ability to understand written or spoken English
- Owning a mobile device
- Ability to understand and consent to study procedures
Who cannot join
- No recent suicidal thoughts or behaviors (i.e., past 2-week suicidal ideation or past 6-month suicidal behaviors)
- Not a current UMass Amherst or University of Wisconsin Madison undergraduate student
- Under 18 years of age
- Inability to understand written or spoken English
- Does not own a mobile device
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
University of Massachusetts Amherst
Amherst, Massachusetts, 01002
About this study
Official title: Advancing Student Suicide Interventions With Scalable Technologies (ASSIST)
Mobile-based applications, such as JasprHealth, can deliver evidence-based skills intended to reduce imminent suicide risk (e.g., reducing means access), improve emotional states (e.g., via distraction and coaching to act opposite to emotions), and reduce feelings of social isolation (e.g., via shared stories), but user engagement is a barrier. The aim of this study was to examine the effects of a technological application resource (Jaspr) relative to human augmentation (Jaspr+, e.g., motivationally focused orientation plus prompts) on acceptability, preliminary effectiveness, and engagement among college students who screen positive for suicide risk.
Read the detailed description
Mobile-based applications, such as Jaspr Health, can deliver evidence-based skills intended to reduce imminent suicide risk (e.g., reducing means access), improve emotional states (e.g., via distraction and coaching to act opposite to emotions), and reduce feelings of social isolation (e.g., via shared stories). Although mobile-device-delivered interventions hold the potential to make interventions widely accessible, user engagement presents a substantial barrier to efficacy. This study, ASSIST: Advancing Student Suicide Interventions with Scalable Technologies, aims to improve engagement with mobile-delivered suicide prevention applications, with the ultimate goal of reducing suicidal thoughts and behaviors in college students. Including human elements alongside Jaspr Health has the potential to improve the uptake of this evidence-based, accessible mobile-device-delivered intervention.
The aim of this study was is to examine the effects of the technological application resource Jaspr tablet application with access to Jaspr at Home (JAH) vs. Jaspr+ human augmentation (e.g., motivationally focused orientation plus prompts) on acceptability, preliminary effectiveness, and engagement among 50 college students who screen positive for suicide risk (n=25 per condition) over the course of 2 months. Candidate mechanisms (e.g., coping skills, self-stigma) will also be assessed. Participants were randomized via the Redcap randomization module, stratified by site.
- Conditions
- Suicidal Ideation, Suicide Attempt, Self-Harm
- Being tested
- Jaspr, Behavioral support
- Keywords
- suicide, self-harm, attempt, ideation, suicidal thought, suicidal plan, crisis intervention, suicide prevention, emotional support, mental health, behavioral health, technology, mobile application, lethal means, safety plan
- Medical subject headings
- Suicidal Ideation, Suicide, Attempted, Self-Injurious Behavior, Suicide, Suicide Prevention, Psychological Well-Being
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
JasprDevice
With assistance from a research staff, the subject will complete self-administered suicide risk assessment on the tablet via Jaspr app, then the subject will engage with suicide-related coping skills and resources that the app provides. Subjects will continue to have access to the coping skills and videos via a mobile app.
Behavioral supportBehavioural
Jaspr conversations will be augmented human-driven behavioral support. Conversations will be guided by motivational interviewing principles. Subjects can sign up to receive JAH mobile app.
Subjects will be prompted with their personalized goals as reminders to use the Jaspr app.
| Study group | Role | What they receive |
|---|---|---|
| Jaspr | Experimental | Subjects in this arm will complete a guided Safety Planning, and Lethal means counseling on the Jaspr app before open access to the Jaspr resource library.
Subjects can sign up to receive Jaspr At Home (JAH) mobile app. Subjects will have continue to have access to treatment as usual through their respective university clinics. Receives: Device: Jaspr |
| Jaspr+ | Experimental | Subjects in this arm will complete a guided Safety Planning, and Lethal means counseling on the Jaspr app before open access to the Jaspr resource library. This will be guided by motivational interviewing principles.
Subjects can sign up to receive Jaspr At Home (JAH0 mobile app. Subjects will be prompted with their personalized goals as reminders to use the Jaspr at home app.
Subjects will have continue to have access to treatment as usual through their respective university clinics. Receives: Device: Jaspr; Behavioral: Behavioral support |
What is being measured
The primary outcome is the main question the study is designed to answer.
Suicidal ideation
Assessed with Suicide Ideation Questionnaire [SIQ], with higher scores reflecting greater past month suicidal ideation.
Measured: weeks 0, 4, 8
Suicidal behaviors
Assessed with the Columbia-Suicide Severity Rating Scale [C-SSRS] self-report screen past week (y = presence /n)
Measured: weeks 0, 1, 2, 3, 4, 8
Secondary outcomes (6)
Suicide-related coping
Assessed with the suicide-related coping scale, [SRCS] with higher scores reflecting a better ability to cope with suicidal thoughts
Measured: weeks 0, 4, 8
Ways of coping
Assessed with the DBT-Ways of Coping Checklist (DBT-WCCL), which yields scales of skills use, general dysfunctional coping, and blaming others, with mean scores of 0-3, with higher levels indicating greater use of those strategies.
Measured: weeks 0, 4, 8
Suicide stigma
Assessed with the personal suicide stigma questionnaire [PSSQ], with higher scores reflecting greater stigma.
Measured: weeks 0, 4, 8
Self-reported engagement
Assessed with item developed for this study, with higher scores reflecting greater engagement in the app.
Measured: weeks 0, 1, 2, 3, 4, 8
Acceptability
Assessed with the Acceptability of Implementation Measure [AIM], with higher scores reflecting whether the intervention is liked, welcomed, or approved.
Measured: weeks 0, 4, 8
Satisfaction with Intervention
Assessed with the Client Satisfaction Questionnaire - 8 [CSQ8], with higher scores reflecting greater satisfaction with the intervention.
Measured: weeks 0, 4, 8
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Oct 2025
- Study start8 Oct 2025
- Primary completion30 Jun 2027 (estimated)
- Study completion30 Jun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (8)Papers the sponsor has linked to this study.
- Other trials for Suicidal IdeationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Massachusetts, Amherst
- Sponsor type
- University, hospital or other
- Collaborators
- University of Wisconsin, Madison, University of Massachusetts, Worcester, National Institute of Mental Health (NIMH)
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07211373
- Sponsor's protocol ID
- UMassIRB6366
- Other IDs
- P50MH129701
- Acronym
- ASSIST
- Status last verified
- Oct 2025
- First submitted
- 1 Oct 2025
- Last updated
- 20 Oct 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
- Individual data sharing
- Yes: The analytic plan and de-identifiable/de-identified data will be shared.
Publications
Weiner BJ, Lewis CC, Stanick C, Powell BJ, Dorsey CN, Clary AS, Boynton MH, Halko H. Psychometric assessment of three newly developed implementation outcome measures. Implement Sci. 2017 Aug 29;12(1):108. doi: 10.1186/s13012-017-0635-3.
PubMed 28851459Posner, K. (2008). Columbia-Suicide Severity Rating Scale. Research Foundation for Mental Hygiene.
Neacsiu AD, Rizvi SL, Vitaliano PP, Lynch TR, Linehan MM. The dialectical behavior therapy ways of coping checklist: development and psychometric properties. J Clin Psychol. 2010 Jun;66(6):563-82. doi: 10.1002/jclp.20685.
PubMed 20455249Maclean BR, Forrester T, Hawgood J, O'Gorman J, Rimkeviciene J. The Personal Suicide Stigma Questionnaire (PSSQ): Relation to Self-Esteem, Well-Being, and Help-Seeking. Int J Environ Res Public Health. 2023 Feb 21;20(5):3816. doi: 10.3390/ijerph20053816.
PubMed 36900827Larsen DL, Attkisson CC, Hargreaves WA, Nguyen TD. Assessment of client/patient satisfaction: development of a general scale. Eval Program Plann. 1979;2(3):197-207. doi: 10.1016/0149-7189(79)90094-6. No abstract available.
PubMed 10245370Kelly PJ, Kyngdon F, Ingram I, Deane FP, Baker AL, Osborne BA. The Client Satisfaction Questionnaire-8: Psychometric properties in a cross-sectional survey of people attending residential substance abuse treatment. Drug Alcohol Rev. 2018 Jan;37(1):79-86. doi: 10.1111/dar.12522. Epub 2017 May 7.
PubMed 28480521Harris PA, Taylor R, Minor BL, Elliott V, Fernandez M, O'Neal L, McLeod L, Delacqua G, Delacqua F, Kirby J, Duda SN; REDCap Consortium. The REDCap consortium: Building an international community of software platform partners. J Biomed Inform. 2019 Jul;95:103208. doi: 10.1016/j.jbi.2019.103208. Epub 2019 May 9.
PubMed 31078660Gellatly J, Bower P, Hennessy S, Richards D, Gilbody S, Lovell K. What makes self-help interventions effective in the management of depressive symptoms? Meta-analysis and meta-regression. Psychol Med. 2007 Sep;37(9):1217-28. doi: 10.1017/S0033291707000062. Epub 2007 Feb 19.
PubMed 17306044
Study at a glance
From the registry record, last updated by the sponsor on 20 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Advancing Student Suicide Interventions With Scalable Technologies (ASSIST)
- ClinicalTrials.gov ID
- NCT07211373
- Acronym / sponsor ID
- ASSIST / UMassIRB6366
- Conditions
- Suicidal Ideation, Suicide Attempt, Self-Harm
- Keywords
- suicide, self-harm, attempt, ideation, suicidal thought, suicidal plan, crisis intervention, suicide prevention
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- University of Massachusetts, AmherstUniversity, hospital or other
- Collaborators
- University of Wisconsin, Madison, University of Massachusetts, Worcester, National Institute of Mental Health (NIMH)
- Study start
- 8 Oct 2025 (actual)
- Primary completion
- 30 Jun 2027 (estimated)
- Study completion
- 30 Jun 2027 (estimated)
- First posted
- 8 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Mobile-based applications, such as JasprHealth, can deliver evidence-based skills intended to reduce imminent suicide risk (e.g., reducing means access), improve emotional states (e.g., via distraction and coaching to act opposite to emotions), and reduce feelings of social isolation (e.g., via shared stories), but user engagement is a barrier. The aim of this study was to examine the effects of a technological application resource (Jaspr) relative to human augmentation (Jaspr+, e.g., motivationally focused orientation plus prompts) on acceptability, preliminary effectiveness, and engagement among college students who screen positive for suicide risk.
Detailed description
Mobile-based applications, such as Jaspr Health, can deliver evidence-based skills intended to reduce imminent suicide risk (e.g., reducing means access), improve emotional states (e.g., via distraction and coaching to act opposite to emotions), and reduce feelings of social isolation (e.g., via shared stories). Although mobile-device-delivered interventions hold the potential to make interventions widely accessible, user engagement presents a substantial barrier to efficacy. This study, ASSIST: Advancing Student Suicide Interventions with Scalable Technologies, aims to improve engagement with mobile-delivered suicide prevention applications, with the ultimate goal of reducing suicidal thoughts and behaviors in college students. Including human elements alongside Jaspr Health has the potential to improve the uptake of this evidence-based, accessible mobile-device-delivered intervention.
The aim of this study was is to examine the effects of the technological application resource Jaspr tablet application with access to Jaspr at Home (JAH) vs. Jaspr+ human augmentation (e.g., motivationally focused orientation plus prompts) on acceptability, preliminary effectiveness, and engagement among 50 college students who screen positive for suicide risk (n=25 per condition) over the course of 2 months. Candidate mechanisms (e.g., coping skills, self-stigma) will also be assessed. Participants were randomized via the Redcap randomization module, stratified by site.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Jaspr | Experimental | Device: JasprSubjects in this arm will complete a guided Safety Planning, and Lethal means counseling on the Jaspr app before open access to the Jaspr resource library. Subjects can sign up to receive Jaspr At Home (JAH) mobile app. Subjects will have continue to have access to treatment as usual through their respective university clinics. |
| Jaspr+ | Experimental | Device: Jaspr, Behavioral: Behavioral supportSubjects in this arm will complete a guided Safety Planning, and Lethal means counseling on the Jaspr app before open access to the Jaspr resource library. This will be guided by motivational interviewing principles. Subjects can sign up to receive Jaspr At Home (JAH0 mobile app. Subjects will be prompted with their personalized goals as reminders to use the Jaspr at home app. Subjects will have continue to have access to treatment as usual through their respective university clinics. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Recent suicidal thoughts or behavior (i.e., past 2-week suicidal ideation or past 6-month suicidal behaviors)
- Current UMass Amherst or University of Wisconsin Madison undergraduate student
- 18 years of age or older
- Ability to understand written or spoken English
- Owning a mobile device
Key exclusion criteria (5 listed)
- No recent suicidal thoughts or behaviors (i.e., past 2-week suicidal ideation or past 6-month suicidal behaviors)
- Not a current UMass Amherst or University of Wisconsin Madison undergraduate student
- Under 18 years of age
- Inability to understand written or spoken English
- Does not own a mobile device
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| JasprWith assistance from a research staff, the subject will complete self-administered suicide risk assessment on the tablet via Jaspr app, then the subject will engage with suicide-related coping skills and resources that the app provides. Subjects will continue to have access to the coping skills and videos via a mobile app. | Device | Jaspr, Jaspr+ |
| Behavioral supportJaspr conversations will be augmented human-driven behavioral support. Conversations will be guided by motivational interviewing principles. Subjects can sign up to receive JAH mobile app. Subjects will be prompted with their personalized goals as reminders to use the Jaspr app. | Behavioural | Jaspr+ |
Primary outcome
Suicidal ideation
Time frame: weeks 0, 4, 8
Assessed with Suicide Ideation Questionnaire [SIQ], with higher scores reflecting greater past month suicidal ideation.
Suicidal behaviors
Time frame: weeks 0, 1, 2, 3, 4, 8
Assessed with the Columbia-Suicide Severity Rating Scale [C-SSRS] self-report screen past week (y = presence /n)
6 secondary outcomes
Suicide-related coping
Time frame: weeks 0, 4, 8
Ways of coping
Time frame: weeks 0, 4, 8
Suicide stigma
Time frame: weeks 0, 4, 8
Self-reported engagement
Time frame: weeks 0, 1, 2, 3, 4, 8
Acceptability
Time frame: weeks 0, 4, 8
Satisfaction with Intervention
Time frame: weeks 0, 4, 8
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Oct 2025.
- Background: PubMed 28851459Weiner BJ, Lewis CC, Stanick C, Powell BJ, Dorsey CN, Clary AS, Boynton MH, Halko H. Psychometric assessment of three newly developed implementation outcome measures. Implement Sci. 2017 Aug 29;12(1):108. doi: 10.1186/s13012-017-0635-3.
- BackgroundPosner, K. (2008). Columbia-Suicide Severity Rating Scale. Research Foundation for Mental Hygiene.
- Background: PubMed 20455249Neacsiu AD, Rizvi SL, Vitaliano PP, Lynch TR, Linehan MM. The dialectical behavior therapy ways of coping checklist: development and psychometric properties. J Clin Psychol. 2010 Jun;66(6):563-82. doi: 10.1002/jclp.20685.
- Background: PubMed 36900827Maclean BR, Forrester T, Hawgood J, O'Gorman J, Rimkeviciene J. The Personal Suicide Stigma Questionnaire (PSSQ): Relation to Self-Esteem, Well-Being, and Help-Seeking. Int J Environ Res Public Health. 2023 Feb 21;20(5):3816. doi: 10.3390/ijerph20053816.
- Background: PubMed 10245370Larsen DL, Attkisson CC, Hargreaves WA, Nguyen TD. Assessment of client/patient satisfaction: development of a general scale. Eval Program Plann. 1979;2(3):197-207. doi: 10.1016/0149-7189(79)90094-6. No abstract available.
- Background: PubMed 28480521Kelly PJ, Kyngdon F, Ingram I, Deane FP, Baker AL, Osborne BA. The Client Satisfaction Questionnaire-8: Psychometric properties in a cross-sectional survey of people attending residential substance abuse treatment. Drug Alcohol Rev. 2018 Jan;37(1):79-86. doi: 10.1111/dar.12522. Epub 2017 May 7.
- Background: PubMed 31078660Harris PA, Taylor R, Minor BL, Elliott V, Fernandez M, O'Neal L, McLeod L, Delacqua G, Delacqua F, Kirby J, Duda SN; REDCap Consortium. The REDCap consortium: Building an international community of software platform partners. J Biomed Inform. 2019 Jul;95:103208. doi: 10.1016/j.jbi.2019.103208. Epub 2019 May 9.
- Background: PubMed 17306044Gellatly J, Bower P, Hennessy S, Richards D, Gilbody S, Lovell K. What makes self-help interventions effective in the management of depressive symptoms? Meta-analysis and meta-regression. Psychol Med. 2007 Sep;37(9):1217-28. doi: 10.1017/S0033291707000062. Epub 2007 Feb 19.
- Individual participant dataSharing planned: Yes. The analytic plan and de-identifiable/de-identified data will be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Jaspr and Behavioral support in people with Suicidal Ideation and Suicide Attempt, run by University of Massachusetts, Amherst at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 20 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Suicidal ideation (time frame: weeks 0, 4, 8). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07211373, which also lists 8 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Oct 2025.