Hypocalcemia After Total ThyroidectomyNCT07211581
Predicting Factors of Post-Total Thyroidectomy Hypocaӏcemia
An observational study of Hypocalcemia After Total Thyroidectomy, run by Al Safwa University College at 1 site in Tunisia.
Trial summary
Predicting post-total thyroidectomy hypocalcemia involves a combination of patient-specific, disease-related, and surgical factors. Key predictive factors include the intrinsic characteristics of the thyroid disease, pre-operative levels of calcium and vitamin D, the degree of parathyroid gland manipulation or injury… Read more about this study
- Who is it for?
- Ages 21 to 76 years
- Conditions the study is for
- Hypocalcemia After Total Thyroidectomy
- What is being tested?
- total thyroidectomy
- Type of treatment
- Surgery or procedure
- How many people
- 123 participants
- Where
- 1 siteTunisia
- Study dates
- 17 Sep 2025to 17 Sep 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 to 76 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: A total of 123 patients who underwent total thyroidectomy for various thyroid diseases were included in the study, performed by a group of surgeons.
Who may be able to join
- patients requiring total thyroidectomy.
- age between 18-75 years old
- both gender
- no co-existing disease.
Who cannot join
- 1. previous hemithyroidectomy, lobectomy, resection of the parathyroid gland. 2. 2. patients with missing laboratory data, previous subtotal thyroidectomy.
- 3. diagnosed pathology of the parathyroid gland
Trial locations and contacts
1 site in 1 country.
About this study
Predicting post-total thyroidectomy hypocalcemia involves a combination of patient-specific, disease-related, and surgical factors. Key predictive factors include the intrinsic characteristics of the thyroid disease, pre-operative levels of calcium and vitamin D, the degree of parathyroid gland manipulation or injury, advanced age, and pre-existing hyperthyroidism. While no single factor is definitive, a low post-operative parathyroid hormone (iPTH) level is a strong indicator of developing hypocalcemia
- Conditions
- Hypocalcemia After Total Thyroidectomy
- Being tested
- total thyroidectomy
- Keywords
- Predicting Factors., Total Thyroidectomy., Hypocalcemia
- Medical subject headings
- Hypocalcemia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
total thyroidectomyProcedure or surgery
both lobes removed and observe the calcemic level
What is being measured
The primary outcome is the main question the study is designed to answer.
hypocalcemia incidence
Measured: 1 day and 2 weeks after surgery
hypocalcemia other factors related to clinical status.
Comparison of Serum Calcium levels of the studied group reported Comparison of PTH levels between hypocaӏcemia and Eucalcemic
Measured: 1 day and 2 weeks after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Oct 2025
- Study start17 Sep 2025
- Primary completion17 Sep 2025
- Study completion17 Sep 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hypocalcemia After Total ThyroidectomyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 123 participants (actual)
Sponsor and investigators
- Lead sponsor
- Al Safwa University College
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohammed AbdulZahra Sasaa, Al Safwa University College
- Investigators
- 1. Ali Fadhil Zaidan, PhD, Study chair, mustaqbal university
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07211581
- Sponsor's protocol ID
- AlSafwaUC
- Status last verified
- Sep 2025
- First submitted
- 17 Sep 2025
- Last updated
- 8 Oct 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Predicting Factors of Post-Total Thyroidectomy Hypocaӏcemia
- ClinicalTrials.gov ID
- NCT07211581
- Acronym / sponsor ID
- AlSafwaUC
- Conditions
- Hypocalcemia After Total Thyroidectomy
- Keywords
- Predicting Factors., Total Thyroidectomy., Hypocalcemia
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 123 participants (actual)
- Lead sponsor
- Al Safwa University CollegeUniversity, hospital or other
- Study start
- 17 Sep 2025 (actual)
- Primary completion
- 17 Sep 2025 (actual)
- Study completion
- 17 Sep 2025 (actual)
- First posted
- 8 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Predicting post-total thyroidectomy hypocalcemia involves a combination of patient-specific, disease-related, and surgical factors. Key predictive factors include the intrinsic characteristics of the thyroid disease, pre-operative levels of calcium and vitamin D, the degree of parathyroid gland manipulation or injury, advanced age, and pre-existing hyperthyroidism. While no single factor is definitive, a low post-operative parathyroid hormone (iPTH) level is a strong indicator of developing hypocalcemia
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 21 to 76 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- A total of 123 patients who underwent total thyroidectomy for various thyroid diseases were included in the study, performed by a group of surgeons.
Key inclusion criteria (4 listed)
- patients requiring total thyroidectomy.
- age between 18-75 years old
- both gender
- no co-existing disease.
Key exclusion criteria (2 listed)
- 1. previous hemithyroidectomy, lobectomy, resection of the parathyroid gland. 2. 2. patients with missing laboratory data, previous subtotal thyroidectomy.
- 3. diagnosed pathology of the parathyroid gland
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| total thyroidectomyboth lobes removed and observe the calcemic level | Procedure or surgery | – |
Primary outcome
hypocalcemia incidence
Time frame: 1 day and 2 weeks after surgery
hypocalcemia other factors related to clinical status.
Time frame: 1 day and 2 weeks after surgery
Comparison of Serum Calcium levels of the studied group reported Comparison of PTH levels between hypocaӏcemia and Eucalcemic
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Oct 2025.
- Individual participant dataSharing planned: No
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COMPARISON OF THE EFFICACY BETWEEN PREOPERATIVE CALCIUM & VITAMIN D3 VERSUS CALCIUM SUPPLEMENTATION ALONE TO PREVENT POST OPERATIVE SYMPTOMATIC HYPOCALCEMIA AFTER TOTAL THYROIDECTOMY IN EUTHYROID PATIENTS
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1. Ali Fadhil Zaidan, PhD study chair
mustaqbal university
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Hypocalcemia After Total Thyroidectomy, run by Al Safwa University College at 1 site in Tunisia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Tunisia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
hypocalcemia incidence (time frame: 1 day and 2 weeks after surgery). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Oct 2025.