Alcohol Use DisorderLDARTNCT07221383
LDART for Alcohol Use Disorder
A study testing LDART in people with Alcohol Use Disorder and Hazardous Alcohol Use, run by Yale University at 1 site in United States.
Trial summary
This study is a pilot randomized controlled trial to evaluate feasibility, acceptability, and preliminary efficacy of a digital intervention called Let's Do Addiction Recovery Together! (LDART) in adults with alcohol use disorder, relative to a control group. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Alcohol Use Disorder, Hazardous Alcohol Use
- What is being tested?
- LDART
- Type of treatment
- Medical device, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 siteUnited States
- Study dates
- 29 Apr 2026to 1 Apr 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Currently reside in Connecticut, USA
- Have a smartphone that can send and receive text messages and have internet access that can be access over the course of a month
- Had ≥5 heavy drinking days (defined as ≥4 or ≥5 drinks in one sitting for women and men, respectively) in the past 28 days
- Alcohol Symptom Checklist ≥4, indicating moderate/severe AUD
- Have some self-reported desire to cut down or quit drinking
Who cannot join
- Unable to provide informed consent, as assessed by the consent quiz
- Unable to speak, read, or write in English
- Vulnerable population status
- Unlikely to be able to complete study procedures in the next 2-3 months
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: A Pilot Randomized Controlled Trial of LDART, a Social Support Intervention for Alcohol Use Disorder
This study is a pilot randomized controlled trial to evaluate feasibility, acceptability, and preliminary efficacy of a digital intervention called Let's Do Addiction Recovery Together! (LDART) in adults with alcohol use disorder, relative to a control group.
- Conditions
- Alcohol Use Disorder, Hazardous Alcohol Use
- Being tested
- LDART, Psychoeducational control
- Keywords
- social support, digital intervention, mutual-help groups, alcohol use disorder, addiction recovery, peer support
- Medical subject headings
- Alcoholism
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
LDARTDevice
Let's Do Addiction Recovery Together! (LDART) is a web-based intervention grounded in social cognitive theory that is designed to reduce hazardous alcohol use. It has three active ingredients: 1) daily recovery goal setting and tracking, 2) motivational video, audio, and written messages from individuals in recovery, and 3) information on several community-based recovery groups (e.g., mutual-help groups, recovery community centers) that provide free, publicly available meetings and activities. Participants receive a text message reminder each night to go to the website to complete the activities, and a text message reminder each morning of the goal they set for themselves, with the option to change it. It only takes a few minutes to use LDART each day over the 4-week intervention period.
Psychoeducational controlBehavioural
This is a 20-page psychoeducational booklet created by the National Institute on Alcohol Abuse \& Alcoholism (NIAAA) called "Rethinking Drinking". It contains several suggestions, strategies and resources for helping people who want to reduce their alcohol use. Participants will be encouraged to access the booklet for a few minutes each night over the 4-week intervention period.
| Study group | Role | What they receive |
|---|---|---|
| LDART | Experimental | Participants will be given access to LDART for 28 days. Receives: Device: LDART |
| Rethinking Drinking | Other | Participants will be emailed a PDF of this psychoeducational booklet. Receives: Behavioral: Psychoeducational control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Recruitment rate
The percentage of eligible participants who are enrolled relative to the total number of eligible potential participants who completed the screening.
Measured: From enrollment to the final assessment time point (Day 56)
Accrual rate
The rate of enrollment, defined as number of participants enrolled per month.
Measured: From enrollment to the final assessment time point (Day 56)
Retention rate
The percentage of enrolled participants who complete all study-related procedures (i.e., assessments at 3 monthly time points).
Measured: From enrollment to the final assessment time point (Day 56)
Intervention engagement
Number of nights that participants in the active condition completed the activities on the LDART website, out of 28 nights.
Measured: From beginning the intervention (Day 1) to the end of the intervention period (Day 28)
Intervention acceptability
Rating scores on the end-user version of the Mobile App Rating Scale (uMARS). Total score range 1-5 with higher scores indicating a better quality app.
Measured: The second assessment time point (post-intervention, Day 28)
Secondary outcomes (3)
Change from baseline in number of drinking days
Change in self-reported number of drinking days in the past 28 days, as measured using the Timeline Follow-back.
Measured: Baseline (Day 0), Post-intervention (Day 28), 1-month post-intervention (Day 56)
Change from baseline in number of heavy drinking days
Change in self-reported number of heavy drinking days (defined as 4 or more drinks for women or 5 or more drinks for in one sitting) in the past 28 days, as measured using the Timeline Follow-back.
Measured: Baseline (Day 0), Post-intervention (Day 28), 1-month post-intervention (Day 56)
Change from baseline in number of hours spent engaging with recovery groups
Self-reported number of hours spent engaging with recovery groups in the past 28 days
Measured: Baseline (Day 0), Post-intervention (Day 28), 1-month post-intervention (Day 56)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Oct 2025
- Study start29 Apr 2026
- Primary completion1 Apr 2027 (estimated)
- Study completion1 Apr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Alcohol Use DisorderStudies of the same condition, open and under way.
- More trials run by Yale UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Yale University
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Responsible party
- Sponsor
- Investigators
- Li Yan McCurdy, PhD, Principal investigator, Yale University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07221383
- Sponsor's protocol ID
- 2000040798
- Other IDs
- K12DA000167
- Acronym
- LDART
- Status last verified
- Apr 2026
- First submitted
- 23 Oct 2025
- Last updated
- 1 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 1 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Pilot Randomized Controlled Trial of LDART, a Social Support Intervention for Alcohol Use Disorder
- ClinicalTrials.gov ID
- NCT07221383
- Acronym / sponsor ID
- LDART / 2000040798
- Conditions
- Alcohol Use Disorder, Hazardous Alcohol Use
- Keywords
- social support, digital intervention, mutual-help groups, alcohol use disorder, addiction recovery, peer support
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Yale UniversityUniversity, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Study start
- 29 Apr 2026 (actual)
- Primary completion
- 1 Apr 2027 (estimated)
- Study completion
- 1 Apr 2027 (estimated)
- First posted
- 27 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is a pilot randomized controlled trial to evaluate feasibility, acceptability, and preliminary efficacy of a digital intervention called Let's Do Addiction Recovery Together! (LDART) in adults with alcohol use disorder, relative to a control group.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| LDART | Experimental | Device: LDARTParticipants will be given access to LDART for 28 days. |
| Rethinking Drinking | Other | Behavioral: Psychoeducational controlParticipants will be emailed a PDF of this psychoeducational booklet. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Currently reside in Connecticut, USA
- Have a smartphone that can send and receive text messages and have internet access that can be access over the course of a month
- Had ≥5 heavy drinking days (defined as ≥4 or ≥5 drinks in one sitting for women and men, respectively) in the past 28 days
- Alcohol Symptom Checklist ≥4, indicating moderate/severe AUD
- Have some self-reported desire to cut down or quit drinking
Key exclusion criteria (4 listed)
- Unable to provide informed consent, as assessed by the consent quiz
- Unable to speak, read, or write in English
- Vulnerable population status
- Unlikely to be able to complete study procedures in the next 2-3 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| LDARTLet's Do Addiction Recovery Together! (LDART) is a web-based intervention grounded in social cognitive theory that is designed to reduce hazardous alcohol use. It has three active ingredients: 1) daily recovery goal setting and tracking, 2) motivational video, audio, and written messages from individuals in recovery, and 3) information on several community-based recovery groups (e.g., mutual-help groups, recovery community centers) that provide free, publicly available meetings and activities. Participants receive a text message reminder each night to go to the website to complete the activities, and a text message reminder each morning of the goal they set for themselves, with the option to change it. It only takes a few minutes to use LDART each day over the 4-week intervention period. | Device | LDART |
| Psychoeducational controlThis is a 20-page psychoeducational booklet created by the National Institute on Alcohol Abuse \& Alcoholism (NIAAA) called "Rethinking Drinking". It contains several suggestions, strategies and resources for helping people who want to reduce their alcohol use. Participants will be encouraged to access the booklet for a few minutes each night over the 4-week intervention period. | Behavioural | Rethinking Drinking |
Primary outcome
Recruitment rate
Time frame: From enrollment to the final assessment time point (Day 56)
The percentage of eligible participants who are enrolled relative to the total number of eligible potential participants who completed the screening.
Accrual rate
Time frame: From enrollment to the final assessment time point (Day 56)
The rate of enrollment, defined as number of participants enrolled per month.
Retention rate
Time frame: From enrollment to the final assessment time point (Day 56)
The percentage of enrolled participants who complete all study-related procedures (i.e., assessments at 3 monthly time points).
Intervention engagement
Time frame: From beginning the intervention (Day 1) to the end of the intervention period (Day 28)
Number of nights that participants in the active condition completed the activities on the LDART website, out of 28 nights.
Intervention acceptability
Time frame: The second assessment time point (post-intervention, Day 28)
Rating scores on the end-user version of the Mobile App Rating Scale (uMARS). Total score range 1-5 with higher scores indicating a better quality app.
3 secondary outcomes
Change from baseline in number of drinking days
Time frame: Baseline (Day 0), Post-intervention (Day 28), 1-month post-intervention (Day 56)
Change from baseline in number of heavy drinking days
Time frame: Baseline (Day 0), Post-intervention (Day 28), 1-month post-intervention (Day 56)
Change from baseline in number of hours spent engaging with recovery groups
Time frame: Baseline (Day 0), Post-intervention (Day 28), 1-month post-intervention (Day 56)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Li Yan McCurdy, PhD principal investigator
Yale University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing LDART in people with Alcohol Use Disorder and Hazardous Alcohol Use, run by Yale University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 1 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Recruitment rate (time frame: From enrollment to the final assessment time point (Day 56)). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 May 2026.