AppendixNCT07229690
Closure of Appendicular Stump
An observational study of Appendix, run by Zagazig University at 1 site in Egypt.
Trial summary
this study compare between different types of appendicular stump closure Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Appendix
- What is being tested?
- endoloop closure and intracorporeal suture
- Type of treatment
- Surgery or procedure
- How many people
- 666 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Mar 2017to 1 Aug 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: patients with complicated acute appendicitis
Who may be able to join
- aged ≥18 years a clinical diagnosis of complicated AA
Who cannot join
- • Pregnancy (n=7)
- Complicated appendicitis secondary to colon caecum (n=2)
- inflammatory bowel disease (n=4)
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Appendicular Stump Closure Techniques
this study compare between different types of appendicular stump closure
- Conditions
- Appendix
- Being tested
- endoloop closure, intracorporeal suture
- Keywords
- appendix, stump
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
endoloop closureProcedure or surgery
closure of stump by endoloop
intracorporeal sutureProcedure or surgery
closure of stump by suture
| Study group | Role | What they receive |
|---|---|---|
| endoloop | closure of stump by endoloop Receives: Procedure: endoloop closure | |
| intracorporeal suture | closure of stump by suture Receives: Procedure: intracorporeal suture |
What is being measured
The primary outcome is the main question the study is designed to answer.
appendicular leak
Measured: 30 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Nov 2025
- Study start1 Mar 2017
- Primary completion1 Aug 2025
- Study completion1 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AppendixStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 666 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zagazig University
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Tamer.A.A.M.Habeeb, Zagazig University
- Investigators
- Tamer.A.A.M. Habeeb, Principal investigator, Zagazig University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07229690
- Sponsor's protocol ID
- appendicular stump closure
- Status last verified
- Nov 2025
- First submitted
- 13 Nov 2025
- Last updated
- 17 Nov 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 17 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Appendicular Stump Closure Techniques
- ClinicalTrials.gov ID
- NCT07229690
- Acronym / sponsor ID
- appendicular stump closure
- Conditions
- Appendix
- Keywords
- appendix, stump
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 666 participants (actual)
- Lead sponsor
- Zagazig UniversityOther government
- Study start
- 1 Mar 2017 (actual)
- Primary completion
- 1 Aug 2025 (actual)
- Study completion
- 1 Aug 2025 (actual)
- First posted
- 17 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
this study compare between different types of appendicular stump closure
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| endoloop | – | Procedure: endoloop closureclosure of stump by endoloop |
| intracorporeal suture | – | Procedure: intracorporeal sutureclosure of stump by suture |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- patients with complicated acute appendicitis
Key inclusion criteria (1 listed)
- aged ≥18 years a clinical diagnosis of complicated AA
Key exclusion criteria (3 listed)
- • Pregnancy (n=7)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| endoloop closureclosure of stump by endoloop | Procedure or surgery | endoloop |
| intracorporeal sutureclosure of stump by suture | Procedure or surgery | intracorporeal suture |
Primary outcome
appendicular leak
Time frame: 30 days
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Nov 2025.
- Individual participant dataSharing planned: Yes
Related trials for Appendix
Active, not recruitingPhase 2
ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis
Appendix Cancer, Colorectal Cancer
Recruiting
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
Ampulla of Vater Carcinoma, Appendix Carcinoma
RecruitingPhase 3
Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial
Metastatic Appendix Carcinoma, Metastatic Colorectal Carcinoma
Recruiting
EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.
Gastrointestinal Cancer, Colon Cancer
Active, not recruitingPhase 2
Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors
Appendix Adenocarcinoma, Human Papillomavirus-Related Anal Squamous Cell Carcinoma
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Tamer.A.A.M. Habeeb principal investigator
Zagazig University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Appendix, run by Zagazig University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
appendicular leak (time frame: 30 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Nov 2025.