Fracture ForearmNCT07234370
Distal Radial Fractures in Adult Patients: 4 Weeks Versus 6 Weeks of Cast Immobilization
A study testing Short Arm Cast for Distal Radius Fracture for four weeks and Short Arm Cast for Distal Radius Fracture for six weeks in people with Fracture Forearm and Radius Distal Fracture, run by Liaquat National Hospital & Medical College at 1 site in Pakistan.
Trial summary
Post-intervention outcomes comparing casting in distal radius fractures of four weeks versus six weeks. Read more about this study
- Who is it for?
- Ages 18 to 50 years
- Conditions the study is for
- Fracture Forearm, Radius Distal Fracture
- What is being tested?
- Short Arm Cast for Distal Radius Fracture for four weeks and Short Arm Cast for Distal Radius Fracture for six weeks
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 sitePakistan
- Study dates
- 15 Sep 2025to 1 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients with DRF undergoing conservative management with cast immobilization
- Age between 18 to 50 years.
Who cannot join
- Any syndromic patients
- Any patients with musculoskeletal disease
- Patients having osteoporosis
- Post-menopausal females
- Smokers
- Ages less than 18 or greater than 50
- Patients presenting with intra-articular fractures
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Distal Radial Fractures in Adult Patients: 4 Weeks Versus 6 Weeks of Cast Immobilization-A Randomized Controlled Trial
Post-intervention outcomes comparing casting in distal radius fractures of four weeks versus six weeks.
Read the detailed description
Cast immobilization for 6 weeks remains the mainstay of therapy for distal radius fractures. To challenge the therapeutic time frame, participants will be randomized into two arms, and the treatment arm will undergo immobilization for 4 weeks. Outcomes will be assessed at cast removal and then at 3 and 6 months prospectively using the Quick-DASH score and the DASH score (only at 6 months).
- Conditions
- Fracture Forearm, Radius Distal Fracture
- Being tested
- Short Arm Cast for Distal Radius Fracture for four weeks, Short Arm Cast for Distal Radius Fracture for six weeks
- Medical subject headings
- Wrist Fractures
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Short Arm Cast for Distal Radius Fracture for four weeksProcedure or surgery
Also called Splint, Cast
Scotch cast immobilization below elbow for four weeks
Short Arm Cast for Distal Radius Fracture for six weeksProcedure or surgery
Also called Splint, Cast
Scotch cast immobilization below elbow for six weeks
| Study group | Role | What they receive |
|---|---|---|
| Cast immobilization for four weeks | Experimental | Scotch cast immobilization for a period of four weeks applied to distal radius fractures. Receives: Procedure: Short Arm Cast for Distal Radius Fracture for four weeks |
| Cast immobilization for six weeks | Active comparator | Scotch cast immobilization for a period of six weeks applied to distal radius fractures Receives: Procedure: Short Arm Cast for Distal Radius Fracture for six weeks |
What is being measured
The primary outcome is the main question the study is designed to answer.
Quick Disability of Arm, Shoulder, and Hand Score (Quick DASH)
Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.
Measured: Four weeks (Cast Removal)
Quick Disability of Arm, Shoulder, and Hand (Quick DASH)
Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.
Measured: Six weeks (Cast Removal)
Quick Disability of Arm, Shoulder, and Hand (Quick DASH)
Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.
Measured: 3 months after cast removal
Quick Disability of Arm, Shoulder, and Hand (Quick DASH)
Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.
Measured: 6 months after cast removal
Disability of Arm, Shoulder, and Hand Score
The Disability of Arm, Shoulder, and Hand Score (DASH) is a 30-item questionnaire with scores ranging from 1 to 5 for each item. The final scores are formulated from 0 to 100, where a higher score indicates greater disability and a lower score indicates little to no disability.
Measured: 6 months post-removal of cast immobilizations
Secondary outcomes (4)
Radial Deviation
Radial deviation ranges from 15-25°. More deviation suggests more joint movement and is associated with better outcomes.
Measured: 6 months post-cast immobilization removal
Ulnar Deviation
Ulnar deviation ranges from 30-45 °. More deviation suggests more joint movement and is associated with better outcomes.
Measured: 6 months post-cast immobilization removal.
Dorsiflexion
Dorsiflexion ranges from 8-26 °. More flexion suggests more joint movement and is associated with better outcomes.
Measured: 6 months post-cast immobilization removal.
Palmar Flexion
Palmar flexion ranges from 70-90 °. More flexion suggests more joint movement and is associated with better outcomes.
Measured: 6 months post-cast immobilization removal.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Nov 2025
- Study start15 Sep 2025
- Primary completion1 Dec 2025 (estimated)
- Study completion1 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Fracture ForearmStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Liaquat National Hospital & Medical College
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohammad Zeeshan Haider, Liaquat National Hospital & Medical College
- Investigators
- Mohammad Nabeel Aamir Syed, MBBS, MD, Principal investigator
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07234370
- Sponsor's protocol ID
- R.C-LNH-Orthpedics-05/2025/52
- Status last verified
- Sep 2025
- First submitted
- 14 Nov 2025
- Last updated
- 24 Nov 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Distal Radial Fractures in Adult Patients: 4 Weeks Versus 6 Weeks of Cast Immobilization-A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07234370
- Acronym / sponsor ID
- R.C-LNH-Orthpedics-05/2025/52
- Conditions
- Fracture Forearm, Radius Distal Fracture
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Liaquat National Hospital & Medical CollegeUniversity, hospital or other
- Study start
- 15 Sep 2025 (actual)
- Primary completion
- 1 Dec 2025 (estimated)
- Study completion
- 1 Feb 2026 (estimated)
- First posted
- 18 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Post-intervention outcomes comparing casting in distal radius fractures of four weeks versus six weeks.
Detailed description
Cast immobilization for 6 weeks remains the mainstay of therapy for distal radius fractures. To challenge the therapeutic time frame, participants will be randomized into two arms, and the treatment arm will undergo immobilization for 4 weeks. Outcomes will be assessed at cast removal and then at 3 and 6 months prospectively using the Quick-DASH score and the DASH score (only at 6 months).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Cast immobilization for four weeks | Experimental | Procedure: Short Arm Cast for Distal Radius Fracture for four weeksScotch cast immobilization for a period of four weeks applied to distal radius fractures. |
| Cast immobilization for six weeks | Active comparator | Procedure: Short Arm Cast for Distal Radius Fracture for six weeksScotch cast immobilization for a period of six weeks applied to distal radius fractures |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Patients with DRF undergoing conservative management with cast immobilization
- Age between 18 to 50 years.
Key exclusion criteria (7 listed)
- Any syndromic patients
- Any patients with musculoskeletal disease
- Patients having osteoporosis
- Post-menopausal females
- Smokers
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Short Arm Cast for Distal Radius Fracture for four weeksAlso: Splint, CastScotch cast immobilization below elbow for four weeks | Procedure or surgery | Cast immobilization for four weeks |
| Short Arm Cast for Distal Radius Fracture for six weeksAlso: Splint, CastScotch cast immobilization below elbow for six weeks | Procedure or surgery | Cast immobilization for six weeks |
Primary outcome
Quick Disability of Arm, Shoulder, and Hand Score (Quick DASH)
Time frame: Four weeks (Cast Removal)
Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.
Quick Disability of Arm, Shoulder, and Hand (Quick DASH)
Time frame: Six weeks (Cast Removal)
Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.
Quick Disability of Arm, Shoulder, and Hand (Quick DASH)
Time frame: 3 months after cast removal
Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.
Quick Disability of Arm, Shoulder, and Hand (Quick DASH)
Time frame: 6 months after cast removal
Quick Disability of Arm, Shoulder, and Hand (Quick DASH) score is calculated using a formula based on responses to an 11-item questionnaire. Scores range from 0 to 100, where 0 indicates no disability and 100 indicates the most severe disability.
Disability of Arm, Shoulder, and Hand Score
Time frame: 6 months post-removal of cast immobilizations
The Disability of Arm, Shoulder, and Hand Score (DASH) is a 30-item questionnaire with scores ranging from 1 to 5 for each item. The final scores are formulated from 0 to 100, where a higher score indicates greater disability and a lower score indicates little to no disability.
4 secondary outcomes
Radial Deviation
Time frame: 6 months post-cast immobilization removal
Ulnar Deviation
Time frame: 6 months post-cast immobilization removal.
Dorsiflexion
Time frame: 6 months post-cast immobilization removal.
Palmar Flexion
Time frame: 6 months post-cast immobilization removal.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Nov 2025.
- Individual participant dataSharing planned: No
Related trials for Fracture Forearm
Recruiting
The With Or Without Olecranon K-wires Trial
Olecranon Fracture
Not yet recruiting
Management of Diaphyseal Forearm Fractures in Adolescents
Forearm Fractures
RecruitingPhase 4
A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements
Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified
Recruiting
Short and Long-arm Fiberglass Cast Immobilization for Distal Salter Harris I and II Forearm Fractures in Children
Fracture Forearm
Not yet recruiting
Time to Healing in Displaced Pediatric Diaphyseal Forearm Fractures Treated With Bioabsorbable Compared to Titanium Intramedullary Nails
Forearm Injuries, Radius Fractures
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mohammad Nabeel Aamir Syed, MBBS, MD principal investigator
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Short Arm Cast for Distal Radius Fracture for four weeks and Short Arm Cast for Distal Radius Fracture for six weeks in people with Fracture Forearm and Radius Distal Fracture, run by Liaquat National Hospital & Medical College at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 24 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Quick Disability of Arm, Shoulder, and Hand Score (Quick DASH) (time frame: Four weeks (Cast Removal)). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Nov 2025.