Ultrasound-guided Fluid ManagementPULSENCT07237347
Perceptions and Ultrasound Literacy for Sound Volume Management
An observational study of Ultrasound-guided Fluid Management and Volume Responsiveness, run by University Hospital, Basel, Switzerland at 1 site in Switzerland.
Trial summary
The aim of this study is to assess the knowledge, attitudes, and practices of ICU physicians in Switzerland regarding the use of ultrasound for fluid management and evaluation of venous congestion. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Ultrasound-guided Fluid Management, Volume Responsiveness, Venous Congestion Assessment
- What is being tested?
- Quastionnaire
- How many people
- 200 participants
- Where
- 1 siteSwitzerland
- Study dates
- 1 Oct 2025to 1 Nov 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Adult, Older adult
Study population: physicians working in Swiss ICUs
Who may be able to join
- physicians working in ICUs
- working in Switzerland
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Switzerland1 site, 1 recruiting
- Recruiting
University Hospital Basel
Basel, 4031
Gregor Loosen, MD, +41 61 55 65194, gregormichael.loosen@usb.ch
About this study
The aim of this study is to assess the knowledge, attitudes, and practices of ICU physicians in Switzerland regarding the use of ultrasound for fluid management and evaluation of venous congestion.
Read the detailed description
This multicenter survey study aims to explore the experiences, perceptions, and attitudes of intensive care unit (ICU) physicians in Switzerland regarding the use of ultrasound for fluid management. The primary objective is to assess participants' knowledge of ultrasound techniques to predict fluid responsiveness and evaluate venous congestion. The study will also compare familiarity with traditional methods (e.g., central venous pressure, IVC-Inferior Vena Cava ultrasound) and newer approaches such as the VEXUS (Venous Excess Ultrasound Score) score or assessment of stroke volume changes during passive leg raise or mini fluid challenges.
Participants will complete an online questionnaire via REDCap, covering demographics, professional background, ultrasound training, knowledge and experience with ultrasound for volume management and venous congestion, as well as institutional factors and suggestions for improvement. The survey will be distributed to physicians working in ICUs at multiple Swiss hospitals, including the University Hospital Basel, Kantonsspital Aarau, Inselspital Bern, Spitalzentrum Biel, and Triemlispital Zürich. Participation is voluntary, and informed consent will be obtained electronically at the start of the questionnaire.
- Conditions
- Ultrasound-guided Fluid Management, Volume Responsiveness, Venous Congestion Assessment, ICU Physician Practices
- Being tested
- Quastionnaire
- Keywords
- Ultrasound, fluid management, volume responsiveness, intensive care
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
QuastionnaireOther
physicians working in ICUs will complete a questionnaire through REDcap
| Study group | Role | What they receive |
|---|---|---|
| ICU staff | physicians working in ICUs in Switzerland Receives: Other: Quastionnaire |
What is being measured
The primary outcome is the main question the study is designed to answer.
Physician Knowledge and Experience Using Ultrasound for Fluid Management and Venous Congestion
The primary outcome is the proportion of ICU physicians in Switzerland who demonstrate knowledge and report regular use of ultrasound techniques for assessing fluid responsiveness and venous congestion, including traditional methods and newer approaches. Data will be collected through a structured online questionnaire.
Measured: completion of questionnaire once within the assessement period, takes about 30 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Nov 2025
- Study start1 Oct 2025
- Primary completion1 Nov 2026 (estimated)
- Study completion1 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Ultrasound-guided Fluid ManagementStudies of the same condition, open and under way.
- More trials run by University Hospital, Basel, SwitzerlandThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Basel, Switzerland
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Gregor Loosen, MD, Principal investigator, University Hospital of Basel
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07237347
- Sponsor's protocol ID
- am25Loosen;Req-2025-00684
- Acronym
- PULSE
- Status last verified
- Dec 2025
- First submitted
- 14 Nov 2025
- Last updated
- 26 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Perceptions and Ultrasound Literacy for Sound Volume Management
- ClinicalTrials.gov ID
- NCT07237347
- Acronym / sponsor ID
- PULSE / am25Loosen;Req-2025-00684
- Conditions
- Ultrasound-guided Fluid Management, Volume Responsiveness, Venous Congestion Assessment, ICU Physician Practices
- Keywords
- Ultrasound, fluid management, volume responsiveness, intensive care
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- University Hospital, Basel, SwitzerlandUniversity, hospital or other
- Study start
- 1 Oct 2025 (actual)
- Primary completion
- 1 Nov 2026 (estimated)
- Study completion
- 1 Nov 2026 (estimated)
- First posted
- 19 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to assess the knowledge, attitudes, and practices of ICU physicians in Switzerland regarding the use of ultrasound for fluid management and evaluation of venous congestion.
Detailed description
This multicenter survey study aims to explore the experiences, perceptions, and attitudes of intensive care unit (ICU) physicians in Switzerland regarding the use of ultrasound for fluid management. The primary objective is to assess participants' knowledge of ultrasound techniques to predict fluid responsiveness and evaluate venous congestion. The study will also compare familiarity with traditional methods (e.g., central venous pressure, IVC-Inferior Vena Cava ultrasound) and newer approaches such as the VEXUS (Venous Excess Ultrasound Score) score or assessment of stroke volume changes during passive leg raise or mini fluid challenges.
Participants will complete an online questionnaire via REDCap, covering demographics, professional background, ultrasound training, knowledge and experience with ultrasound for volume management and venous congestion, as well as institutional factors and suggestions for improvement. The survey will be distributed to physicians working in ICUs at multiple Swiss hospitals, including the University Hospital Basel, Kantonsspital Aarau, Inselspital Bern, Spitalzentrum Biel, and Triemlispital Zürich. Participation is voluntary, and informed consent will be obtained electronically at the start of the questionnaire.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| ICU staff | – | Other: Quastionnairephysicians working in ICUs in Switzerland |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- physicians working in Swiss ICUs
Key inclusion criteria (2 listed)
- physicians working in ICUs
- working in Switzerland
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Quastionnairephysicians working in ICUs will complete a questionnaire through REDcap | Other | ICU staff |
Primary outcome
Physician Knowledge and Experience Using Ultrasound for Fluid Management and Venous Congestion
Time frame: completion of questionnaire once within the assessement period, takes about 30 minutes
The primary outcome is the proportion of ICU physicians in Switzerland who demonstrate knowledge and report regular use of ultrasound techniques for assessing fluid responsiveness and venous congestion, including traditional methods and newer approaches. Data will be collected through a structured online questionnaire.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Gregor Loosen, MD principal investigator
University Hospital of Basel
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Ultrasound-guided Fluid Management and Volume Responsiveness, run by University Hospital, Basel, Switzerland at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 26 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Gregor Loosen, MD (+41 61 55 65194, gregormichael.loosen@usb.ch), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Physician Knowledge and Experience Using Ultrasound for Fluid Management and Venous Congestion (time frame: completion of questionnaire once within the assessement period, takes about 30 minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Aug 2026.