StrokeNCT07244952
Effects of Vojta Therapy on Posture and Trunk Control
A study testing Vojta therapy and Routine physical therapy in people with Stroke and Stroke Ischemic, run by University of Lahore at 1 site in Pakistan.
Trial summary
Vojta therapy that is reflex locomotion therapy is a neurophysiological rehabilitation approach that stimulates specific "reflex zones" on the body to activate global, innate movement patterns. Read more about this study
- Who is it for?
- Ages 45 to 65 years
- Conditions the study is for
- Stroke, Stroke Ischemic
- What is being tested?
- Vojta therapy and Routine physical therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 62 participants
- Where
- 1 sitePakistan
- Study dates
- 15 Nov 2025to 30 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age 45-65 years
- Both males and females
- First time subacute stroke (7 days post stroke to 3 months)
- Brunnstrom stage 1,2
- A confirmed CT scan for subacute ischemic stroke
- A hemiplegia with score of ≤2 of medical research council scale for muscle strength of the arm (MRCS)
Show all 10Show fewer
- Premorbid modified Rankin scale score ≤ 3
- Stroke patient who can achieve supported standing
- Patients having NIHSS score 16-20 will be included
- Patient who can achieve sitting for 30 seconds
Who cannot join
- Severe cognitive impairments that can hinder rehabilitation
- Limitations in communication due to aphasia
- Altered consciousness or dementia (Epple et al., 2020b)
- Patients suffering from postural hypotension
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Dr Wajeeha Mahmood (PT)
Lahore
Wajeeha Mahmood, BSPT, PPDPT, MSNMPT, 03349867317, 70137173@student.uol.edu.pk
70137173@student.uol.edu.pk
About this study
Official title: Effects of Vojta Therapy on Posture and Trunk Control in Patients With Sub-acute Stroke
Vojta therapy that is reflex locomotion therapy is a neurophysiological rehabilitation approach that stimulates specific "reflex zones" on the body to activate global, innate movement patterns. In stroke rehabilitation, it is used to improve postural control, trunk stability, and functional movement by engaging automatic motor responses. Vojta stimulation can activate motor cortical and subcortical areas as well as postural muscles. Pose estimation will be used to analyze human motion in stroke patients. The study will identify if there is significant difference in the comparative effects of Vojta therapy in addition to routine physical therapy on posture, trunk control and upper extremity motor function in sub-acute stroke patients
Read the detailed description
Vojta therapy can be used in the early stages of stroke patients' rehabilitation because acute stroke patients are characterized by a disruption in their capacity to react to changes in body posture, necessitating automatic postural adjustment. This study will determine the comparative effects of Vojta therapy in addition to routine physical therapy on posture, trunk control and upper extremity motor function in patients with sub-acute stroke. Body angles will be measured used Vojta therapy.
- Conditions
- Stroke, Stroke Ischemic
- Being tested
- Vojta therapy, Routine physical therapy
- Keywords
- Stroke, cerebral vascular accident, Vojta therapy, pose estimation, posture control, trunk control, upper extremity function
- Medical subject headings
- Stroke, Ischemic Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Vojta therapyOther
Also called Reflex locomotion therapy
Vojta therapy will be implemented for reflex rolling and reflex creeping. A small pressure with dorsal, medial and cranial directional stimuli will be provided. After stimulation the reactions are extension of spine, flexion of hip joint, then knee joint and in the end at ankle joint. 5 sessions per week with a 60-minute session are part of protocol for routine physical therapy and vojta therapy for 8 weeks.
Routine physical therapyOther
The control group will receive routine physical therapy treatment which will consist of positioning, passive movements of the limbs, sensorimotor exercises for the affected limb using task-oriented training and motor relearning program consisting of repetitive motor skills consisting of functional tasks and involves task breakdown, such as transfers, upper limb function will be performed. 5 sessions per week with a 60-minute session are part of protocol for routine physical therapy and core stability for 8 weeks.
| Study group | Role | What they receive |
|---|---|---|
| Experimental arm | Experimental | Vojta therapy and routine physical therapy Receives: Other: Vojta therapy; Other: Routine physical therapy |
| Conventional therapy arm | Active comparator | Routine physical therapy Receives: Other: Routine physical therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Posture control
To measure posture control posture assessment scale for stroke will be used. It will determine posture after stroke in sitting, standing and lying position. It's a 4-point scale and ranges from 0-36. It consists of 12 items where items are scored from 0-3.It will measure balance in sitting, standing and lying. It will measure the ability of the individual to maintain balance with different positions. Inter ratter reliability for individual items is α=0.88. It has excellent predictive validity with α=0.86
Measured: 8 weeks
Trunk control
Trunk performance will be assessed with Trunk control test. It consists of four items assessed on a three-point ordinal scale. Items include rolling to affected and non-affected side, sitting, and balance in the sitting position for 30 seconds. The total score is from 0 to 100, a higher score of 50 points indicates better performance. A 12-point score indicates abnormal pattern of movement while a 25 -point score means movement was normal. Internal validity is a= o.86 while r= 0.76 It is a validated test for posture control and motor
Measured: 8 weeks
Motor Evaluation Scale for upper extremity
Motor evaluation scale for upper extremity will be used to measure motor activity of arm and hand. It has 8 tasks for arm with six categories of responses and hand has 6 tasks items with three categories. While functional tasks have three items with three categories. It has items of arm with total score of 40 and hand items with total score of 18. The maximum score for the scale is 58. The scale has good test-retest reliability. Reliability is 0.99 for MESUPES arm and 0.97 for MESUPES hand. Validity is 0.87
Measured: 8 weeks
Pose estimation
Pose estimation software will be used for posture information. It will use key points as joints from the body and their position in space and time. In pose estimation the position of each body joint is estimated. It is based on activity recognition. The recognition is done by segmenting the position of the key points of the joints of the individuals in the scene. The Smart phone cameras are used for picture and then the software recognizes the key points on the picture. The software will record precise posture information. The program uses user-selected images to determine angles between various body components
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Nov 2025
- Study start15 Nov 2025
- Primary completion15 Aug 2026 (estimated)
- Study completion30 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 62 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Wajeeha Mahmood, University of Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07244952
- Sponsor's protocol ID
- UOL/IREB/25/12/0031
- Status last verified
- Nov 2025
- First submitted
- 17 Nov 2025
- Last updated
- 28 Nov 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Vojta Therapy on Posture and Trunk Control in Patients With Sub-acute Stroke
- ClinicalTrials.gov ID
- NCT07244952
- Acronym / sponsor ID
- UOL/IREB/25/12/0031
- Conditions
- Stroke, Stroke Ischemic
- Keywords
- Stroke, cerebral vascular accident, Vojta therapy, pose estimation, posture control, trunk control, upper extremity function
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 62 participants (estimated)
- Lead sponsor
- University of LahoreUniversity, hospital or other
- Study start
- 15 Nov 2025 (actual)
- Primary completion
- 15 Aug 2026 (estimated)
- Study completion
- 30 Aug 2026 (estimated)
- First posted
- 24 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Vojta therapy that is reflex locomotion therapy is a neurophysiological rehabilitation approach that stimulates specific "reflex zones" on the body to activate global, innate movement patterns. In stroke rehabilitation, it is used to improve postural control, trunk stability, and functional movement by engaging automatic motor responses. Vojta stimulation can activate motor cortical and subcortical areas as well as postural muscles. Pose estimation will be used to analyze human motion in stroke patients. The study will identify if there is significant difference in the comparative effects of Vojta therapy in addition to routine physical therapy on posture, trunk control and upper extremity motor function in sub-acute stroke patients
Detailed description
Vojta therapy can be used in the early stages of stroke patients' rehabilitation because acute stroke patients are characterized by a disruption in their capacity to react to changes in body posture, necessitating automatic postural adjustment. This study will determine the comparative effects of Vojta therapy in addition to routine physical therapy on posture, trunk control and upper extremity motor function in patients with sub-acute stroke. Body angles will be measured used Vojta therapy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Experimental arm | Experimental | Other: Vojta therapy, Other: Routine physical therapyVojta therapy and routine physical therapy |
| Conventional therapy arm | Active comparator | Other: Routine physical therapyRoutine physical therapy |
Who may qualify
- Ages
- 45 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (10 listed)
- Age 45-65 years
- Both males and females
- First time subacute stroke (7 days post stroke to 3 months)
- Brunnstrom stage 1,2
- A confirmed CT scan for subacute ischemic stroke
Key exclusion criteria (4 listed)
- Severe cognitive impairments that can hinder rehabilitation
- Limitations in communication due to aphasia
- Altered consciousness or dementia (Epple et al., 2020b)
- Patients suffering from postural hypotension
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Vojta therapyAlso: Reflex locomotion therapyVojta therapy will be implemented for reflex rolling and reflex creeping. A small pressure with dorsal, medial and cranial directional stimuli will be provided. After stimulation the reactions are extension of spine, flexion of hip joint, then knee joint and in the end at ankle joint. 5 sessions per week with a 60-minute session are part of protocol for routine physical therapy and vojta therapy for 8 weeks. | Other | Experimental arm |
| Routine physical therapyThe control group will receive routine physical therapy treatment which will consist of positioning, passive movements of the limbs, sensorimotor exercises for the affected limb using task-oriented training and motor relearning program consisting of repetitive motor skills consisting of functional tasks and involves task breakdown, such as transfers, upper limb function will be performed. 5 sessions per week with a 60-minute session are part of protocol for routine physical therapy and core stability for 8 weeks. | Other | Conventional therapy arm, Experimental arm |
Primary outcome
Posture control
Time frame: 8 weeks
To measure posture control posture assessment scale for stroke will be used. It will determine posture after stroke in sitting, standing and lying position. It's a 4-point scale and ranges from 0-36. It consists of 12 items where items are scored from 0-3.It will measure balance in sitting, standing and lying. It will measure the ability of the individual to maintain balance with different positions. Inter ratter reliability for individual items is α=0.88. It has excellent predictive validity with α=0.86
Trunk control
Time frame: 8 weeks
Trunk performance will be assessed with Trunk control test. It consists of four items assessed on a three-point ordinal scale. Items include rolling to affected and non-affected side, sitting, and balance in the sitting position for 30 seconds. The total score is from 0 to 100, a higher score of 50 points indicates better performance. A 12-point score indicates abnormal pattern of movement while a 25 -point score means movement was normal. Internal validity is a= o.86 while r= 0.76 It is a validated test for posture control and motor
Motor Evaluation Scale for upper extremity
Time frame: 8 weeks
Motor evaluation scale for upper extremity will be used to measure motor activity of arm and hand. It has 8 tasks for arm with six categories of responses and hand has 6 tasks items with three categories. While functional tasks have three items with three categories. It has items of arm with total score of 40 and hand items with total score of 18. The maximum score for the scale is 58. The scale has good test-retest reliability. Reliability is 0.99 for MESUPES arm and 0.97 for MESUPES hand. Validity is 0.87
Pose estimation
Time frame: 8 weeks
Pose estimation software will be used for posture information. It will use key points as joints from the body and their position in space and time. In pose estimation the position of each body joint is estimated. It is based on activity recognition. The recognition is done by segmenting the position of the key points of the joints of the individuals in the scene. The Smart phone cameras are used for picture and then the software recognizes the key points on the picture. The software will record precise posture information. The program uses user-selected images to determine angles between various body components
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Nov 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Vojta therapy and Routine physical therapy in people with Stroke and Stroke Ischemic, run by University of Lahore at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 10 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Wajeeha Mahmood, BSPT,PPDPT,MSNMPT (03349867317, 70137173@student.uol.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Posture control (time frame: 8 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Nov 2025.