Spiritual CareNCT07246954
A Chaplain-clinician Led Spiritual Care (PEACE) Intervention on Spiritual/Religious Beliefs Related to Medical Care in Patients With Advanced Cancer: a Pilot Clinical Trial
A study testing Peace Intervention in people with Spiritual Care and Advanced Cancer, run by M.D. Anderson Cancer Center at 1 site in United States.
Trial summary
To examine the feasibility and acceptability of chaplain-clinician led spiritual care (PEACE: Perception, Exploring, Addressing, Compassionate Connection, Embracing) intervention in patients with advanced cancer. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Spiritual Care, Advanced Cancer
- What is being tested?
- Peace Intervention
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteUnited States
- Study dates
- 22 Dec 2025to 1 Jan 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Eligibility Criteria
- Participants with advanced cancer (locally advanced, metastatic, recurrent, or incurable) seen by the participant supportive/palliative care mobile team at MD Anderson Cancer Center.
- Respond "somewhat to A great deal" to the question in the RBEC questionnaire "I will accept every possible medical treatment because my faith tells me to do everything I can to stay alive longer".
- Participant s aged 18 years or over.
- Karnofsky performance status ≥30% at time of inclusion into study.
- Normal cognitive status as determined by the supportive care clinicians based on the ability to understand the nature of the study and consent process.
- Only English-speaking, as determined by their ability to understand the informed consent, the intervention, and the assessment tools.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
MD Anderson Cancer Center
Houston, Texas, 77030
Marvin Delgado Guay, MD, 713-745-8190, marvin.delgado@mdanderson.org
Marvin Delgado Guay, MD
About this study
To examine the feasibility and acceptability of chaplain-clinician led spiritual care (PEACE: Perception, Exploring, Addressing, Compassionate Connection, Embracing) intervention in patients with advanced cancer.
Read the detailed description
Primary Objectives
(Phase 1): To examine the feasibility and acceptability of a Chaplain-Clinician led spiritual care (PEACE: Perception, Exploring, Addressing, Compassionate Connection, Embracing) intervention in patients with advanced cancer admitted to a comprehensive cancer center in a single-arm pilot trial. Evaluation of feasibility will be per ≥70% participation in all sessions.
Acceptability will be assessed as ≥70% reporting satisfaction and ≥70% recommending PEACE intervention to others at the post-treatment assessment.
(Phase 2): To examine the within-group change in the influence of spiritual/religious beliefs on medical care (Question 2 in the Religious Beliefs in End-of-Life Medical Care [RBEC] tool: I will accept every possible medical treatment because my faith tells me to do everything I can to stay alive longer) from baseline to post-intervention assessments at 2 + 1 days in participants who participate in the PEACE intervention group and the usual care group.
- Conditions
- Spiritual Care, Advanced Cancer
- Being tested
- Peace Intervention, Usual Care
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Peace InterventionOther
Patients will participate in two PEACE intervention sessions, which will last 30-60 minutes each.
Usual CareOther
Usual care is a comprehensive evaluation of the physical, emotional, and spiritual needs of the patient by the Supportive/Palliative Care medical team.
| Study group | Role | What they receive |
|---|---|---|
| Phase 1 | Experimental | Patients will participate in two PEACE intervention sessions, which will last 30-60 minutes each. Receives: Other: Peace Intervention |
| Phase 2 | Experimental | Usual care is a comprehensive evaluation of the physical, emotional, and spiritual needs of the patient by the Supportive/Palliative Care medical team Receives: Other: Peace Intervention; Other: Usual Care |
What is being measured
The primary outcome is the main question the study is designed to answer.
RBEC Questionnaire
Measured: Through study completion; an average of 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Nov 2025
- Study start22 Dec 2025
- Primary completion1 Jan 2027 (estimated)
- Study completion1 Jan 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Spiritual CareStudies of the same condition, open and under way.
- More trials run by M.D. Anderson Cancer CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- M.D. Anderson Cancer Center
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Marvin Delgado Guay, MD, Principal investigator, M.D. Anderson Cancer Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07246954
- Sponsor's protocol ID
- 2025-1052
- Other IDs
- NCI-2025-08254
- Status last verified
- Sep 2026
- First submitted
- 4 Nov 2025
- Last updated
- 25 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Chaplain-clinician Led Spiritual Care (PEACE) Intervention on Spiritual/Religious Beliefs Related to Medical Care in Patients With Advanced Cancer: a Pilot Clinical Trial
- ClinicalTrials.gov ID
- NCT07246954
- Acronym / sponsor ID
- 2025-1052
- Conditions
- Spiritual Care, Advanced Cancer
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- M.D. Anderson Cancer CenterUniversity, hospital or other
- Study start
- 22 Dec 2025 (actual)
- Primary completion
- 1 Jan 2027 (estimated)
- Study completion
- 1 Jan 2029 (estimated)
- First posted
- 24 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To examine the feasibility and acceptability of chaplain-clinician led spiritual care (PEACE: Perception, Exploring, Addressing, Compassionate Connection, Embracing) intervention in patients with advanced cancer.
Detailed description
Primary Objectives
(Phase 1): To examine the feasibility and acceptability of a Chaplain-Clinician led spiritual care (PEACE: Perception, Exploring, Addressing, Compassionate Connection, Embracing) intervention in patients with advanced cancer admitted to a comprehensive cancer center in a single-arm pilot trial. Evaluation of feasibility will be per ≥70% participation in all sessions.
Acceptability will be assessed as ≥70% reporting satisfaction and ≥70% recommending PEACE intervention to others at the post-treatment assessment.
(Phase 2): To examine the within-group change in the influence of spiritual/religious beliefs on medical care (Question 2 in the Religious Beliefs in End-of-Life Medical Care [RBEC] tool: I will accept every possible medical treatment because my faith tells me to do everything I can to stay alive longer) from baseline to post-intervention assessments at 2 + 1 days in participants who participate in the PEACE intervention group and the usual care group.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Phase 1 | Experimental | Other: Peace InterventionPatients will participate in two PEACE intervention sessions, which will last 30-60 minutes each. |
| Phase 2 | Experimental | Other: Peace Intervention, Other: Usual CareUsual care is a comprehensive evaluation of the physical, emotional, and spiritual needs of the patient by the Supportive/Palliative Care medical team |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Peace InterventionPatients will participate in two PEACE intervention sessions, which will last 30-60 minutes each. | Other | Phase 1, Phase 2 |
| Usual CareUsual care is a comprehensive evaluation of the physical, emotional, and spiritual needs of the patient by the Supportive/Palliative Care medical team. | Other | Phase 2 |
Primary outcome
RBEC Questionnaire
Time frame: Through study completion; an average of 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Sep 2026.
- MD Anderson Cancer CenterLink provided by the sponsor.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Marvin Delgado Guay, MD principal investigator
M.D. Anderson Cancer Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Peace Intervention in people with Spiritual Care and Advanced Cancer, run by M.D. Anderson Cancer Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 25 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Marvin Delgado Guay, MD (713-745-8190, marvin.delgado@mdanderson.org), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
RBEC Questionnaire (time frame: Through study completion; an average of 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Sep 2026.