Placenta Accrete SpectrumNCT07250412
The Accuracy Of 3D Color Ultrasonography for Detecting the Degree of Placenta Accreta Spectrum Invasion
A study testing Cesarian section in people with Placenta Accrete Spectrum, run by Sohag University at 1 site in Egypt.
Trial summary
To evaluate the correlation between preoperative ultrasound imaging findings by 3D Color Doppler Ultrasound and the intraoperative severity of Placenta Accreta Spectrum (PAS) disorders, in order to assess the diagnostic accuracy of sonographic markers and their utility in predicting the extent of placental invasion. Read more about this study
- Who is it for?
- Ages 16 to 45 years, women only
- Conditions the study is for
- Placenta Accrete Spectrum
- What is being tested?
- Cesarian section
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Sep 2025to 1 Mar 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 to 45 years
- Women only
- No healthy volunteers
- Child, Adult
Inclusion Criteria: Pregnant women with clinical or ultrasound suspicion of PAS, including:
- Placenta previa or low-lying placenta
- History of previous cesarean section(s) or uterine surgery (e.g., myomectomy, D\&C) 2. Gestational age ≥ 28 weeks at the time of ultrasound evaluation 3. Undergoing planned cesarean delivery in the study hospital 4. Availability of preoperative ultrasound imaging performed using a standardized protocol.
- Patient can provide informed Written consent and Agree to participate in the study - Exclusion Criteria: Patients with incomplete or poor-quality ultrasound data 2. Unavailability of intraoperative confirmation of placental invasion 3. Patients with placental abruption or other causes of acute bleeding requiring emergency delivery without imaging 4. Loss to follow-up prior to delivery 5. Declined consent or withdrew participation from the study -
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
To evaluate the correlation between preoperative ultrasound imaging findings by 3D Color Doppler Ultrasound and the intraoperative severity of Placenta Accreta Spectrum (PAS) disorders, in order to assess the diagnostic accuracy of sonographic markers and their utility in predicting the extent of placental invasion.
- Conditions
- Placenta Accrete Spectrum
- Being tested
- Cesarian section
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cesarian sectionProcedure or surgery
Cesarian section for detection the degree of placenta Accreta spectrum invasion comparaple to 3D color Doppler
| Study group | Role | What they receive |
|---|---|---|
| Ultrasonography | Active comparator | Not described Receives: Procedure: Cesarian section |
What is being measured
The primary outcome is the main question the study is designed to answer.
Correlation between preoperative ultrasound findings and the confirmed degree of Placenta Accreta Spectrum (PAS) severity (classified as accreta, increta, or percreta). o The classification will be based on intraoperative surgical findings.
Measured: Patient preg 28 wks compare finding intraoperative
Correlation between preoperative ultrasound findings and the confirmed degree of Placenta Accreta Spectrum (PAS) severity (classified as accreta, increta, or percreta). o The classification will be based on intraoperative surgical findings.
Measured: Pt preg for more than 28wks preg and compare finding intraoperative
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Nov 2025
- Study start10 Sep 2025
- Primary completion10 Sep 2025
- Study completion1 Mar 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Placenta Accrete SpectrumStudies of the same condition, open and under way.
- More trials run by Sohag UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sohag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohamed Atef Ahmed, Sohag University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07250412
- Sponsor's protocol ID
- Soh-med-25-8____12MS
- Status last verified
- Sep 2025
- First submitted
- 30 Sep 2025
- Last updated
- 26 Nov 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 26 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Accuracy Of 3D Color Ultrasonography for Detecting the Degree of Placenta Accreta Spectrum Invasion
- ClinicalTrials.gov ID
- NCT07250412
- Acronym / sponsor ID
- Soh-med-25-8____12MS
- Conditions
- Placenta Accrete Spectrum
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Sohag UniversityUniversity, hospital or other
- Study start
- 10 Sep 2025 (actual)
- Primary completion
- 10 Sep 2025 (actual)
- Study completion
- 1 Mar 2026 (estimated)
- First posted
- 26 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To evaluate the correlation between preoperative ultrasound imaging findings by 3D Color Doppler Ultrasound and the intraoperative severity of Placenta Accreta Spectrum (PAS) disorders, in order to assess the diagnostic accuracy of sonographic markers and their utility in predicting the extent of placental invasion.
Study design
- Primary purpose
- Diagnosis
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Ultrasonography | Active comparator | Procedure: Cesarian section |
Who may qualify
- Ages
- 16 to 45 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cesarian sectionCesarian section for detection the degree of placenta Accreta spectrum invasion comparaple to 3D color Doppler | Procedure or surgery | Ultrasonography |
Primary outcome
Correlation between preoperative ultrasound findings and the confirmed degree of Placenta Accreta Spectrum (PAS) severity (classified as accreta, increta, or percreta). o The classification will be based on intraoperative surgical findings.
Time frame: Patient preg 28 wks compare finding intraoperative
Correlation between preoperative ultrasound findings and the confirmed degree of Placenta Accreta Spectrum (PAS) severity (classified as accreta, increta, or percreta). o The classification will be based on intraoperative surgical findings.
Time frame: Pt preg for more than 28wks preg and compare finding intraoperative
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Nov 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cesarian section in people with Placenta Accrete Spectrum, run by Sohag University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 26 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Correlation between preoperative ultrasound findings and the confirmed degree of Placenta Accreta Spectrum (PAS) severity (classified as accreta, increta, or percreta). o The classification will be based on intraoperative surgical findings. (time frame: Patient preg 28 wks compare finding intraoperative). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Nov 2025.