Congenital Ectopia LentisNCT07252349
Influence of Different Needle Insertion Positions on the Clinical Efficacy of Suture-Fixated Transscleral IOL Implantation Without Knots
A study testing Transscleral Suture-Fixated Intraocular Lens Implantation (Suture Needle Insertion at 2.5 mm Posterior to the Limbus) in people with Congenital Ectopia Lentis, run by Zhongshan Ophthalmic Center, Sun Yat-sen University at 1 site in China.
Trial summary
This is a single-blind, single-center, parallel-group randomized controlled trial with the following objectives: First, researchers aim to compare the clinical efficacy of 2mm and 2.5mm post-limbal needle insertion in sutureless transscleral IOL fixation for patients with congenital ectopia lentis. Read more about this study
- Who is it for?
- Ages 4 to 18 years
- Conditions the study is for
- Congenital Ectopia Lentis
- What is being tested?
- Transscleral Suture-Fixated Intraocular Lens Implantation (Suture Needle Insertion at 2.5 mm Posterior to the Limbus)
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 54 participants
- Where
- 1 siteChina
- Study dates
- 25 Dec 2025to 31 Aug 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 4 to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Who may be able to join
- Patients aged 4-18 years (regardless of gender) who meet the indications for transscleral suture-fixated intraocular lens implantation
- Patients who can complete a follow-up period of at least 3 months after surgery;
- Patients or their legal guardians who provide informed consent to participate in this study.
Who cannot join
- Patients with concurent secondary qlaucoma, retinal detachment, strabismus, or other relevant ocular complications (excludingrefractive errors);
- Patients participating in other trials that may affect the results of this study.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site
Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology andVisual Science, Guangzhou, Guangdong
Guangdong, Province, 510060
Guangming Jin, +86 13560035613, jinguangming@gzzoc.com
About this study
Official title: Influence of Different Needle Insertion Positions on the Clinical Efficacy of Suture-Fixated Transscleral IOL Implantation Without Knots: A Randomized Controlled Trial
This is a single-blind, single-center, parallel-group randomized controlled trial with the following objectives: First, researchers aim to compare the clinical efficacy of 2mm and 2.5mm post-limbal needle insertion in sutureless transscleral IOL fixation for patients with congenital ectopia lentis. Second, the goal is to investigate the mean absolute refractive prediction error, IOL tilt and decentration, uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), and corneal endothelial cell count at 3 months postoperatively. Third, it intends to explore the incidence of postoperative complications of the two needle insertion positions in this specific surgical method. Finally, this study aims to provide evidence for ophthalmic clinical practice, explore the optimal needle insertion point, and offer more precise and safe surgical plans for patients requiring sutureless transscleral IOL fixation.
Read the detailed description
This is a professional translation conforming to medical academic writing standards (with unified key terms and specified abbreviation as required):
For patients with insufficient capsular bag support due to congenital developmental abnormalities, trauma, or other reasons, who have indications for intraocular lens (IOL) implantation, IOL suspension surgery is the main surgical method. Sutureless transscleral IOL fixation is one of the commonly used IOL suspension surgeries currently. Compared with traditional transscleral suture fixation, sutureless transscleral IOL fixation can effectively reduce suture-related complications while ensuring safety and effectiveness, with higher surgical safety.
In transscleral IOL fixation, previous studies have commonly used 2mm and 2.5mm post-limbal positions as needle insertion sites. The 2.5mm post-limbal needle insertion point has a smaller mean absolute refractive prediction error and better clinical efficacy postoperatively. As an IOL suspension surgery, differences in needle insertion positions may affect postoperative refractive status, IOL stability, visual outcomes, and other parameters. Although existing literature has evaluated the overall clinical efficacy and safety of sutureless transscleral IOL fixation, to date, no study has systematically compared the clinical efficacy of this commonly used IOL suspension surgery at different needle insertion positions. Therefore, evaluating the impact of different needle insertion positions on surgical outcomes is crucial for optimizing surgical strategies and improving treatment precision.
In this randomized controlled trial, the investigators will systematically investigate the clinical efficacy of 2mm and 2.5mm post-limbal needle insertion points in sutureless transscleral IOL fixation. Through this study, the investigators aim to provide evidence for ophthalmic clinical practice, explore the optimal needle insertion point, and offer more precise and safe surgical plans for patients requiring sutureless transscleral IOL fixation.
- Conditions
- Congenital Ectopia Lentis
- Being tested
- Transscleral Suture-Fixated Intraocular Lens Implantation (Suture Needle Insertion at 2.5 mm Posterior to the Limbus)
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Transscleral Suture-Fixated Intraocular Lens Implantation (Suture Needle Insertion at 2.5 mm Posterior to the Limbus)Procedure or surgery
Participants in the intervention group should complete a comprehensive ophthalmic examination at baseline, undergo needle insertion 2.5mm post-limbal during surgery, and receive routine follow-up at 1 week, 1 month, and 3 months postoperatively.
| Study group | Role | What they receive |
|---|---|---|
| intervention group | Experimental | Participants in the intervention group should complete a comprehensive ophthalmic examination at baseline, undergo needle insertion 2.5mm post-limbal during surgery, and receive routine follow-up at 1 week, 1 month, and 3 months postoperatively. Receives: Procedure: Transscleral Suture-Fixated Intraocular Lens Implantation (Suture Needle Insertion at 2.5 mm Posterior to the Limbus) |
| compare group | No intervention | Participants in the intervention group should complete a comprehensive ophthalmic examination at baseline, undergo needle insertion 2mm post-limbal during surgery, and receive routine follow-up at 1 week, 1 month, and 3 months postoperatively. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Refractive Predictive Error of Patients at the 3-month Postoperative Follow-up
Case report form records
Measured: 3-month Postoperative Follow-up
Secondary outcomes (4)
Uncorrected Visual Acuity (UCVA) and Best-Corrected Visual Acuity (BCVA) of Patients at the 3-Month Postoperative Follow-up
Measured using the EDTRS chart
Measured: 3-month Postoperative Follow-up
lOL Tilt and Decentration in Patients at the 3-Month Postoperative Follow-up
Measured by the Casia 2 AS-OCT Instrument
Measured: 3-month Postoperative Follow-up
Corneal Endothelial Cell Count of Patients at the 3-Month Postoperative Follow-up
Measured using a corneal endothelial microscope
Measured: 3-month Postoperative Follow-up
Incidence of Postoperative Complications at the 3-Month Postoperative Follow-up
Measured: 3-month Postoperative Follow-up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Nov 2025
- Study start25 Dec 2025 (estimated)
- Primary completion3 Feb 2027 (estimated)
- Study completion31 Aug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (13)Papers the sponsor has linked to this study.
- Other trials for Congenital Ectopia LentisStudies of the same condition, open and under way.
- More trials run by Zhongshan Ophthalmic Center, Sun Yat-sen UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 54 participants (estimated)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Guangming Jin, Zhongshan Ophthalmic Center, Sun Yat-sen University
- Investigators
- Danying Zheng, Study chair, Guangdong Provincial Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology, ZhongshanOphthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual SodGuangzhou, GuangdongGuangming Jin, Principal investigator, Guangdong Provincial Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology, ZhongshanOphthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangzhou, Guangdong
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07252349
- Sponsor's protocol ID
- 2025KYPJ136
- Status last verified
- Oct 2025
- First submitted
- 18 Nov 2025
- Last updated
- 18 Dec 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Publications
Qu Y, Duan P, Huo S, Li F, Li J. Sutured Intrascleral Posterior Chamber Intraocular Lens Fixation with Ciliary Sulcus Location Guided by Ultrasonic Biological Microscopy: A Retrospective Analysis of Anatomical and Refractive Outcome. J Ophthalmol. 2020 Jun 4;2020:5843410. doi: 10.1155/2020/5843410. eCollection 2020.
PubMed 32587761Kim J, Lee PY, Park MS, Cho BJ, Kwon S. Comparison of outcomes between modified double-flanged sutureless scleral fixation and conventional sutured scleral fixation. Sci Rep. 2024 Jul 12;14(1):16111. doi: 10.1038/s41598-024-66762-y.
PubMed 38997328Yoon EG, Eom Y, Woo M, Jeon HS, Kim SJ, Song JS, Kim HM. Clinical Outcomes of Intrascleral Fixation of Intraocular Lens Compared to Ciliary Sulcus Implantation and Transscleral Fixation. Korean J Ophthalmol. 2023 Apr;37(2):128-136. doi: 10.3341/kjo.2022.0093. Epub 2023 Feb 9.
PubMed 36758538Dubinsky-Pertzov B, Mahler OS, Hecht I, Shemer A, Or L, Gazit I, Pras E, Einan-Lifshitz A. Accuracy of Intraocular Lens Calculation Formulas for the Four-Flanged Fixation Technique in Eyes With No Capsular Support. J Refract Surg. 2022 Oct;38(10):668-673. doi: 10.3928/1081597X-20220919-01. Epub 2022 Oct 1.
PubMed 36214349Leuzinger-Dias M, Lima-Fontes M, Rodrigues R, Oliveira-Ferreira C, Madeira C, Falcao-Reis F, Fernandes V, Rocha-Sousa A, Falcao M. Scleral Fixation of Akreos AO60 Intraocular Lens Using Gore-Tex Suture: An Eye on Visual Outcomes and Postoperative Complications. J Ophthalmol. 2021 Dec 20;2021:9349323. doi: 10.1155/2021/9349323. eCollection 2021.
PubMed 34966559Micheletti JM, Weber N, McCauley MB, Doe EA, Coffee RE, Caplan MB. Punch and rescue technique for scleral fixation of dislocated single-piece intraocular lenses. J Cataract Refract Surg. 2022 Feb 1;48(2):247-250. doi: 10.1097/j.jcrs.0000000000000845.
PubMed 34670946Zeilinger J, Kronschlager M, Schlatter A, Ruiss M, Bayer N, Findl O. Influence of Sutureless Scleral Fixation Techniques With 3-Piece Intraocular Lenses on Dislocation Force. Am J Ophthalmol. 2024 Aug;264:229-234. doi: 10.1016/j.ajo.2024.03.001. Epub 2024 Mar 10.
PubMed 38461946Shi J, Zong Y, Wu K, Jiang C. Simplified Technique for Correcting Intraocular Lens Decentration in Scleral-Sutured Fixation Surgery. Retina. 2025 Jan 17. doi: 10.1097/IAE.0000000000004401. Online ahead of print.
PubMed 39841916Lee KRCK, Fung AT. Four-point subconjunctival scleral fixation technique using Gore-Tex suture. Clin Exp Ophthalmol. 2021 May;49(4):397-399. doi: 10.1111/ceo.13938. Epub 2021 May 11. No abstract available.
PubMed 33913234Dogan L, Edhem Yilmaz I. Quaternary Knot Technique: Suture Knot Burial without Scleral Flap or Incision for Trans-scleral Fixation. J Ophthalmic Vis Res. 2023 Jul 28;18(3):342-347. doi: 10.18502/jovr.v18i3.13784. eCollection 2023 Jul-Sep.
PubMed 37600913Czajka MP, Frajdenberg A, Johansson B. Technique for Sutured Scleral Fixation of One-Piece Hydrophobic Acrylic Intraocular Lenses Dislocated Into the Vitreous. Retina. 2023 Aug 1;43(8):1413-1416. doi: 10.1097/IAE.0000000000003008.
PubMed 33149099Byun Z, Kim DI, Kong M. LONG-TERM ANALYSIS OF INTRASCLERAL FIXATION OF INTRAOCULAR LENS: Trocar-Cannula-Based Sutureless Intrascleral Fixation Versus Sutured Scleral Fixation. Retina. 2023 May 1;43(5):815-822. doi: 10.1097/IAE.0000000000003721.
PubMed 36728892Choi HJ, Kwon OW, Byeon SH, Song JH. Clinical outcomes of combined pars plana vitrectomy and scleral fixation of the intraocular lens with a suspension bridge method in eyes with aphakia or insufficient capsular support. Acta Ophthalmol. 2021 Nov;99(7):e1006-e1012. doi: 10.1111/aos.14758. Epub 2021 Jan 9.
PubMed 33421312
Study at a glance
From the registry record, last updated by the sponsor on 18 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influence of Different Needle Insertion Positions on the Clinical Efficacy of Suture-Fixated Transscleral IOL Implantation Without Knots: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07252349
- Acronym / sponsor ID
- 2025KYPJ136
- Conditions
- Congenital Ectopia Lentis
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 54 participants (estimated)
- Lead sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen UniversityUniversity, hospital or other
- Study start
- 25 Dec 2025 (estimated)
- Primary completion
- 3 Feb 2027 (estimated)
- Study completion
- 31 Aug 2027 (estimated)
- First posted
- 26 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a single-blind, single-center, parallel-group randomized controlled trial with the following objectives: First, researchers aim to compare the clinical efficacy of 2mm and 2.5mm post-limbal needle insertion in sutureless transscleral IOL fixation for patients with congenital ectopia lentis. Second, the goal is to investigate the mean absolute refractive prediction error, IOL tilt and decentration, uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), and corneal endothelial cell count at 3 months postoperatively. Third, it intends to explore the incidence of postoperative complications of the two needle insertion positions in this specific surgical method. Finally, this study aims to provide evidence for ophthalmic clinical practice, explore the optimal needle insertion point, and offer more precise and safe surgical plans for patients requiring sutureless transscleral IOL fixation.
Detailed description
This is a professional translation conforming to medical academic writing standards (with unified key terms and specified abbreviation as required):
For patients with insufficient capsular bag support due to congenital developmental abnormalities, trauma, or other reasons, who have indications for intraocular lens (IOL) implantation, IOL suspension surgery is the main surgical method. Sutureless transscleral IOL fixation is one of the commonly used IOL suspension surgeries currently. Compared with traditional transscleral suture fixation, sutureless transscleral IOL fixation can effectively reduce suture-related complications while ensuring safety and effectiveness, with higher surgical safety.
In transscleral IOL fixation, previous studies have commonly used 2mm and 2.5mm post-limbal positions as needle insertion sites. The 2.5mm post-limbal needle insertion point has a smaller mean absolute refractive prediction error and better clinical efficacy postoperatively. As an IOL suspension surgery, differences in needle insertion positions may affect postoperative refractive status, IOL stability, visual outcomes, and other parameters. Although existing literature has evaluated the overall clinical efficacy and safety of sutureless transscleral IOL fixation, to date, no study has systematically compared the clinical efficacy of this commonly used IOL suspension surgery at different needle insertion positions. Therefore, evaluating the impact of different needle insertion positions on surgical outcomes is crucial for optimizing surgical strategies and improving treatment precision.
In this randomized controlled trial, the investigators will systematically investigate the clinical efficacy of 2mm and 2.5mm post-limbal needle insertion points in sutureless transscleral IOL fixation. Through this study, the investigators aim to provide evidence for ophthalmic clinical practice, explore the optimal needle insertion point, and offer more precise and safe surgical plans for patients requiring sutureless transscleral IOL fixation.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| intervention group | Experimental | Procedure: Transscleral Suture-Fixated Intraocular Lens Implantation (Suture Needle Insertion at 2.5 mm Posterior to the Limbus)Participants in the intervention group should complete a comprehensive ophthalmic examination at baseline, undergo needle insertion 2.5mm post-limbal during surgery, and receive routine follow-up at 1 week, 1 month, and 3 months postoperatively. |
| compare group | No intervention | –Participants in the intervention group should complete a comprehensive ophthalmic examination at baseline, undergo needle insertion 2mm post-limbal during surgery, and receive routine follow-up at 1 week, 1 month, and 3 months postoperatively. |
Who may qualify
- Ages
- 4 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Key inclusion criteria (3 listed)
- Patients aged 4-18 years (regardless of gender) who meet the indications for transscleral suture-fixated intraocular lens implantation
- Patients who can complete a follow-up period of at least 3 months after surgery;
- Patients or their legal guardians who provide informed consent to participate in this study.
Key exclusion criteria (2 listed)
- Patients with concurent secondary qlaucoma, retinal detachment, strabismus, or other relevant ocular complications (excludingrefractive errors);
- Patients participating in other trials that may affect the results of this study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Transscleral Suture-Fixated Intraocular Lens Implantation (Suture Needle Insertion at 2.5 mm Posterior to the Limbus)Participants in the intervention group should complete a comprehensive ophthalmic examination at baseline, undergo needle insertion 2.5mm post-limbal during surgery, and receive routine follow-up at 1 week, 1 month, and 3 months postoperatively. | Procedure or surgery | intervention group |
Primary outcome
Refractive Predictive Error of Patients at the 3-month Postoperative Follow-up
Time frame: 3-month Postoperative Follow-up
Case report form records
4 secondary outcomes
Uncorrected Visual Acuity (UCVA) and Best-Corrected Visual Acuity (BCVA) of Patients at the 3-Month Postoperative Follow-up
Time frame: 3-month Postoperative Follow-up
lOL Tilt and Decentration in Patients at the 3-Month Postoperative Follow-up
Time frame: 3-month Postoperative Follow-up
Corneal Endothelial Cell Count of Patients at the 3-Month Postoperative Follow-up
Time frame: 3-month Postoperative Follow-up
Incidence of Postoperative Complications at the 3-Month Postoperative Follow-up
Time frame: 3-month Postoperative Follow-up
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Dec 2025.
- Results publication: PubMed 32587761Qu Y, Duan P, Huo S, Li F, Li J. Sutured Intrascleral Posterior Chamber Intraocular Lens Fixation with Ciliary Sulcus Location Guided by Ultrasonic Biological Microscopy: A Retrospective Analysis of Anatomical and Refractive Outcome. J Ophthalmol. 2020 Jun 4;2020:5843410. doi: 10.1155/2020/5843410. eCollection 2020.
- Results publication: PubMed 38997328Kim J, Lee PY, Park MS, Cho BJ, Kwon S. Comparison of outcomes between modified double-flanged sutureless scleral fixation and conventional sutured scleral fixation. Sci Rep. 2024 Jul 12;14(1):16111. doi: 10.1038/s41598-024-66762-y.
- Results publication: PubMed 36758538Yoon EG, Eom Y, Woo M, Jeon HS, Kim SJ, Song JS, Kim HM. Clinical Outcomes of Intrascleral Fixation of Intraocular Lens Compared to Ciliary Sulcus Implantation and Transscleral Fixation. Korean J Ophthalmol. 2023 Apr;37(2):128-136. doi: 10.3341/kjo.2022.0093. Epub 2023 Feb 9.
- Results publication: PubMed 36214349Dubinsky-Pertzov B, Mahler OS, Hecht I, Shemer A, Or L, Gazit I, Pras E, Einan-Lifshitz A. Accuracy of Intraocular Lens Calculation Formulas for the Four-Flanged Fixation Technique in Eyes With No Capsular Support. J Refract Surg. 2022 Oct;38(10):668-673. doi: 10.3928/1081597X-20220919-01. Epub 2022 Oct 1.
- Results publication: PubMed 34966559Leuzinger-Dias M, Lima-Fontes M, Rodrigues R, Oliveira-Ferreira C, Madeira C, Falcao-Reis F, Fernandes V, Rocha-Sousa A, Falcao M. Scleral Fixation of Akreos AO60 Intraocular Lens Using Gore-Tex Suture: An Eye on Visual Outcomes and Postoperative Complications. J Ophthalmol. 2021 Dec 20;2021:9349323. doi: 10.1155/2021/9349323. eCollection 2021.
- Results publication: PubMed 34670946Micheletti JM, Weber N, McCauley MB, Doe EA, Coffee RE, Caplan MB. Punch and rescue technique for scleral fixation of dislocated single-piece intraocular lenses. J Cataract Refract Surg. 2022 Feb 1;48(2):247-250. doi: 10.1097/j.jcrs.0000000000000845.
- Results publication: PubMed 38461946Zeilinger J, Kronschlager M, Schlatter A, Ruiss M, Bayer N, Findl O. Influence of Sutureless Scleral Fixation Techniques With 3-Piece Intraocular Lenses on Dislocation Force. Am J Ophthalmol. 2024 Aug;264:229-234. doi: 10.1016/j.ajo.2024.03.001. Epub 2024 Mar 10.
- Results publication: PubMed 39841916Shi J, Zong Y, Wu K, Jiang C. Simplified Technique for Correcting Intraocular Lens Decentration in Scleral-Sutured Fixation Surgery. Retina. 2025 Jan 17. doi: 10.1097/IAE.0000000000004401. Online ahead of print.
- Results publication: PubMed 33913234Lee KRCK, Fung AT. Four-point subconjunctival scleral fixation technique using Gore-Tex suture. Clin Exp Ophthalmol. 2021 May;49(4):397-399. doi: 10.1111/ceo.13938. Epub 2021 May 11. No abstract available.
- Results publication: PubMed 37600913Dogan L, Edhem Yilmaz I. Quaternary Knot Technique: Suture Knot Burial without Scleral Flap or Incision for Trans-scleral Fixation. J Ophthalmic Vis Res. 2023 Jul 28;18(3):342-347. doi: 10.18502/jovr.v18i3.13784. eCollection 2023 Jul-Sep.
- Results publication: PubMed 33149099Czajka MP, Frajdenberg A, Johansson B. Technique for Sutured Scleral Fixation of One-Piece Hydrophobic Acrylic Intraocular Lenses Dislocated Into the Vitreous. Retina. 2023 Aug 1;43(8):1413-1416. doi: 10.1097/IAE.0000000000003008.
- Results publication: PubMed 36728892Byun Z, Kim DI, Kong M. LONG-TERM ANALYSIS OF INTRASCLERAL FIXATION OF INTRAOCULAR LENS: Trocar-Cannula-Based Sutureless Intrascleral Fixation Versus Sutured Scleral Fixation. Retina. 2023 May 1;43(5):815-822. doi: 10.1097/IAE.0000000000003721.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Danying Zheng study chair
Guangdong Provincial Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology, ZhongshanOphthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual SodGuangzhou, Guangdong
Guangming Jin principal investigator
Guangdong Provincial Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology, ZhongshanOphthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangzhou, Guangdong
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Transscleral Suture-Fixated Intraocular Lens Implantation (Suture Needle Insertion at 2.5 mm Posterior to the Limbus) in people with Congenital Ectopia Lentis, run by Zhongshan Ophthalmic Center, Sun Yat-sen University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 18 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Guangming Jin (+86 13560035613, jinguangming@gzzoc.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Refractive Predictive Error of Patients at the 3-month Postoperative Follow-up (time frame: 3-month Postoperative Follow-up). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07252349, which also lists 13 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Dec 2025.