Implant OcclusionNCT07256379
Influence of Two Different Occlusal Schemes Following Single Molar Implant-supported Restorations.
A study testing Maximum Intercusption and Protective occlusion in people with Implant Occlusion, run by International Dental Contiuing Education at 1 site in Egypt.
Trial summary
Occlusal overload may lead to a number of complications; biological and mechanical such as crestal bone loss, screw loosening, prosthetic fracture and even implant failure . Inadequate occlusal scheme (occlusion) causes occlusal overload increasing mechanical stresses which are transferred to the crestal bone and… Read more about this study
- Who is it for?
- Ages 18 to 50 years
- Conditions the study is for
- Implant Occlusion
- What is being tested?
- Maximum Intercusption and Protective occlusion
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 24 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Oct 2023to 1 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients who have a single posterior (1st or second molar) bounded implant with opposing natural tooth teeth.
- Adults above the age of 18.
- Good oral hygiene.
- Patient accepts to provide informed consent.
Who cannot join
- Smokers.
- Pregnant and lactating females.
- Medically compromised patients.
- Patients with untreated active periodontal diseases.
- Patients with parafunctional habits.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Influence of Two Different Occlusal Schemes on Radiographic and Clinical Outcomes Following Single Molar Implant-supported Restorations. A 2-years Randomized Controlled Trial.
Occlusal overload may lead to a number of complications; biological and mechanical such as crestal bone loss, screw loosening, prosthetic fracture and even implant failure . Inadequate occlusal scheme (occlusion) causes occlusal overload increasing mechanical stresses which are transferred to the crestal bone and implant interface, leading to complications such as; Early implant failure, Early crestal bone loss, Intermediate to late implant failure, Intermediate to late implant bone loss, Screw loosening (abutment and prosthesis coping), Uncemented restoration, Component fracture, Porcelain fracture, Prosthesis fracture and Peri implant disease .Thus, a proper implant occlusal scheme plays a major role in the outcome of the implant treatment modality.
- Conditions
- Implant Occlusion
- Being tested
- Maximum Intercusption, Protective occlusion
- Keywords
- Implant Occlusion, protective occlusion
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Maximum IntercusptionProcedure or surgery
to evaluate crestal bone loss, chewing efficiency and prosthetic complications after single posterior implant restoration in protective occlusion in comparison to maximum intercuspation occlusion.
Protective occlusionProcedure or surgery
To evaluate crestal bone loss, chewing efficiency and prosthetic complications after single posterior implant restoration in protective occlusion in comparison to maximum intercuspation occlusion.
| Study group | Role | What they receive |
|---|---|---|
| Protective occlusion | Active comparator | According to the literature, Misch introduced the concept of implant-protective occlusion (IPO) (Misch and Bidez, 1994) based on basic prosthetic concepts, bone biomechanical principles and finite element analysis, which refers to an occlusal scheme designed for implant restoration, promoting the conditions for less biomechanical complications by reducing the stress to the implant interface and enhancing the longevity of the implant and prosthesis. It mainly entails the elimination of premature occlusal contacts or interferences. Receives: Procedure: Protective occlusion |
| Maximum Intercuspation | Experimental | Not described Receives: Procedure: Maximum Intercusption |
What is being measured
The primary outcome is the main question the study is designed to answer.
Marginal Bone Loss
- To evaluate marginal bone loss using bitewing radiographs in mm.
Measured: 2 years
Stability
- to assess implant micromotion in both groups by resonance frequency analysis (Osstell®) in mm.
Measured: 2 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Dec 2025
- Study start1 Oct 2023
- Primary completion1 Nov 2025
- Study completion1 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Implant OcclusionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 24 participants (actual)
Sponsor and investigators
- Lead sponsor
- International Dental Contiuing Education
- Sponsor type
- Research network
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07256379
- Sponsor's protocol ID
- IDCE-16112025
- Status last verified
- Jun 2026
- First submitted
- 20 Nov 2025
- Last updated
- 26 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influence of Two Different Occlusal Schemes on Radiographic and Clinical Outcomes Following Single Molar Implant-supported Restorations. A 2-years Randomized Controlled Trial.
- ClinicalTrials.gov ID
- NCT07256379
- Acronym / sponsor ID
- IDCE-16112025
- Conditions
- Implant Occlusion
- Keywords
- Implant Occlusion, protective occlusion
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 24 participants (actual)
- Lead sponsor
- International Dental Contiuing EducationResearch network
- Study start
- 1 Oct 2023 (actual)
- Primary completion
- 1 Nov 2025 (actual)
- Study completion
- 1 Dec 2025 (actual)
- First posted
- 1 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Occlusal overload may lead to a number of complications; biological and mechanical such as crestal bone loss, screw loosening, prosthetic fracture and even implant failure . Inadequate occlusal scheme (occlusion) causes occlusal overload increasing mechanical stresses which are transferred to the crestal bone and implant interface, leading to complications such as; Early implant failure, Early crestal bone loss, Intermediate to late implant failure, Intermediate to late implant bone loss, Screw loosening (abutment and prosthesis coping), Uncemented restoration, Component fracture, Porcelain fracture, Prosthesis fracture and Peri implant disease .Thus, a proper implant occlusal scheme plays a major role in the outcome of the implant treatment modality.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Protective occlusion | Active comparator | Procedure: Protective occlusionAccording to the literature, Misch introduced the concept of implant-protective occlusion (IPO) (Misch and Bidez, 1994) based on basic prosthetic concepts, bone biomechanical principles and finite element analysis, which refers to an occlusal scheme designed for implant restoration, promoting the conditions for less biomechanical complications by reducing the stress to the implant interface and enhancing the longevity of the implant and prosthesis. It mainly entails the elimination of premature occlusal contacts or interferences. |
| Maximum Intercuspation | Experimental | Procedure: Maximum Intercusption |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Patients who have a single posterior (1st or second molar) bounded implant with opposing natural tooth teeth.
- Adults above the age of 18.
- Good oral hygiene.
- Patient accepts to provide informed consent.
Key exclusion criteria (5 listed)
- Smokers.
- Pregnant and lactating females.
- Medically compromised patients.
- Patients with untreated active periodontal diseases.
- Patients with parafunctional habits.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Maximum Intercusptionto evaluate crestal bone loss, chewing efficiency and prosthetic complications after single posterior implant restoration in protective occlusion in comparison to maximum intercuspation occlusion. | Procedure or surgery | Maximum Intercuspation |
| Protective occlusionTo evaluate crestal bone loss, chewing efficiency and prosthetic complications after single posterior implant restoration in protective occlusion in comparison to maximum intercuspation occlusion. | Procedure or surgery | Protective occlusion |
Primary outcome
Marginal Bone Loss
Time frame: 2 years
• To evaluate marginal bone loss using bitewing radiographs in mm.
Stability
Time frame: 2 years
• to assess implant micromotion in both groups by resonance frequency analysis (Osstell®) in mm.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jun 2026.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Maximum Intercusption and Protective occlusion in people with Implant Occlusion, run by International Dental Contiuing Education at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Marginal Bone Loss (time frame: 2 years). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jun 2026.