ShockNCT07264374
Femoral Vein, Internal Jugular Vein and Inferior Vein Cava Collapsibility Indices in Polytrauma Patients by Sonographic Evaluation Before and After Resuscitation.
An observational study of Shock and Hyopvolemia, run by Assiut University at 1 site in Egypt.
Trial summary
The aim of this study is to evaluate correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED by sonographic evaluation before and after resuscitation. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Shock, Hyopvolemia
- What is being tested?
- Ultrasound assesment of FV,IJV and IVC collabsibillity indecis
- Type of treatment
- Medical device
- How many people
- 50 participants
- Where
- 1 siteEgypt
- Study dates
- 15 Dec 2025to 15 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The study population will include adult patients aged 18-65 years presenting with shock to the emergency department and requiring volume status assessment through both IVC,FV and IJV collabsibility indecis by ultrasound.
Who may be able to join
- Adult patients aged ≥ 18years. ( Patients presented by hypovolemic shock
Who cannot join
- Patient refusal Body Mass Index > 40 kg/m2. Cardiac patients or cardiac tamponade Aortic injury or for cardio-thoracic emergent operation Patients with abdominal mass or other pathology as abdominal collection. Any patient needs emergent surgical intervention History of pulmonary artery hypertension. Femoral vein occlusion. Pregnancy. Pulmonary oedema. Patients will need mechanical ventilation.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site
Emeregency medicine department ,Assiut University
Asyut, Weledea
Mahmoud Ahmed Abdelrady Mahmoud, M.B.B.Ch, 20+01013174106, ammmahmoud1998@gmail.com
About this study
Official title: Comparative Study of Femoral Vein, Internal Jugular Vein and Inferior Vein Cava Collapsibility Indices in Polytrauma Patients Presenting to the Emergency Department by Sonographic Evaluation Before and After Resuscitation.
The aim of this study is to evaluate correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED by sonographic evaluation before and after resuscitation.
Read the detailed description
Polytrauma patients often present with hemodynamic instability where rapid and accurate assessment of intravascular volume is crucial. Central venous pressure monitoring, though considered a standard, is invasive and not always feasible in emergency settings. Point-of-care ultrasound (POCUS) provides a non-invasive alternative through assessment of venous collapsibility indices.
The inferior vena cava (IVC) collapsibility index is commonly used, but its evaluation may be limited in cases of abdominal trauma, obesity, or technical difficulties. The internal jugular vein (IJV) and femoral vein (FV) are superficial, easily accessible, and may provide reliable alternatives.
This study aims to compare the collapsibility indices of the IVC, IJV, and FV in polytrauma patients before and after resuscitation using sonographic evaluation. The objective is to determine their relative accuracy and feasibility as non-invasive markers of intravascular volume status to guide resuscitation in emergency settings.
- Conditions
- Shock, Hyopvolemia
- Being tested
- Ultrasound assesment of FV,IJV and IVC collabsibillity indecis
- Medical subject headings
- Shock
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound assesment of FV,IJV and IVC collabsibillity indecisDevice
Ultrasound-Guided Inferior Vena Cava,femoral vein and internal jugular vein collabsibilty indecis Assessment This intervention involves bedside ultrasound measurement of the inferior vena cava (IVC) diameter and calculation of the IVC collapsibility/distensibility index. Assessments will be performed both at initial presentation and after fluid resuscitation in shock patients. The procedure is non-invasive, rapid, and performed according to standardized emergency ultrasound protocols.
What is being measured
The primary outcome is the main question the study is designed to answer.
correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED before and after resuscitation.
Measured: correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients at time of presentation to the ED and after one hour of resuscitation.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Dec 2025
- Study start15 Dec 2025 (estimated)
- Primary completion15 Nov 2026 (estimated)
- Study completion15 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ShockStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mahmoud Ahmed Abdelrady Mahmoud, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07264374
- Sponsor's protocol ID
- FV-IJV-IVC-CI-shocked-2025
- Status last verified
- Sep 2025
- First submitted
- 1 Oct 2025
- Last updated
- 4 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Study of Femoral Vein, Internal Jugular Vein and Inferior Vein Cava Collapsibility Indices in Polytrauma Patients Presenting to the Emergency Department by Sonographic Evaluation Before and After Resuscitation.
- ClinicalTrials.gov ID
- NCT07264374
- Acronym / sponsor ID
- FV-IJV-IVC-CI-shocked-2025
- Conditions
- Shock, Hyopvolemia
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 15 Dec 2025 (estimated)
- Primary completion
- 15 Nov 2026 (estimated)
- Study completion
- 15 Dec 2026 (estimated)
- First posted
- 4 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to evaluate correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED by sonographic evaluation before and after resuscitation.
Detailed description
Polytrauma patients often present with hemodynamic instability where rapid and accurate assessment of intravascular volume is crucial. Central venous pressure monitoring, though considered a standard, is invasive and not always feasible in emergency settings. Point-of-care ultrasound (POCUS) provides a non-invasive alternative through assessment of venous collapsibility indices.
The inferior vena cava (IVC) collapsibility index is commonly used, but its evaluation may be limited in cases of abdominal trauma, obesity, or technical difficulties. The internal jugular vein (IJV) and femoral vein (FV) are superficial, easily accessible, and may provide reliable alternatives.
This study aims to compare the collapsibility indices of the IVC, IJV, and FV in polytrauma patients before and after resuscitation using sonographic evaluation. The objective is to determine their relative accuracy and feasibility as non-invasive markers of intravascular volume status to guide resuscitation in emergency settings.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The study population will include adult patients aged 18-65 years presenting with shock to the emergency department and requiring volume status assessment through both IVC,FV and IJV collabsibility indecis by ultrasound.
Key inclusion criteria (1 listed)
- Adult patients aged ≥ 18years. ( Patients presented by hypovolemic shock
Key exclusion criteria (1 listed)
- Patient refusal Body Mass Index > 40 kg/m2. Cardiac patients or cardiac tamponade Aortic injury or for cardio-thoracic emergent operation Patients with abdominal mass or other pathology as abdominal collection. Any patient needs emergent surgical intervention History of pulmonary artery hypertension. Femoral vein occlusion. Pregnancy. Pulmonary oedema. Patients will need mechanical ventilation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound assesment of FV,IJV and IVC collabsibillity indecisUltrasound-Guided Inferior Vena Cava,femoral vein and internal jugular vein collabsibilty indecis Assessment This intervention involves bedside ultrasound measurement of the inferior vena cava (IVC) diameter and calculation of the IVC collapsibility/distensibility index. Assessments will be performed both at initial presentation and after fluid resuscitation in shock patients. The procedure is non-invasive, rapid, and performed according to standardized emergency ultrasound protocols. | Device | – |
Primary outcome
correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED before and after resuscitation.
Time frame: correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients at time of presentation to the ED and after one hour of resuscitation.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Dec 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Shock and Hyopvolemia, run by Assiut University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 4 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mahmoud Ahmed Abdelrady Mahmoud, M.B.B.Ch (20+01013174106, ammmahmoud1998@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED before and after resuscitation. (time frame: correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients at time of presentation to the ED and after one hour of resuscitation.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Dec 2025.