FormaldehydeDETOXANAPATHNCT07264504
Experimentation of Formaldehyde Purification by Plants in the Anatomy and Cytology Department
A study testing Biological measurement of urinary formic acid and Plant installation in people with Formaldehyde and Pathological Anatomy and Cytology, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
Trial summary
Formaldehyde is notably used as a tissue fixator in pathological anatomy. Despite its toxicity, it continues to be widely used because it is currently not substitutable. Some plants have shown their ability to absorb formaldehyde. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Formaldehyde, Pathological Anatomy and Cytology
- What is being tested?
- Biological measurement of urinary formic acid and Plant installation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteFrance
- Study dates
- 25 Sep 2024to May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- To work in the Department of Pathological Anatomy and Cytology
- Adult (> 18 years old)
- Patient information and collection of non-opposition
Who cannot join
- Pregnant woman
- Patients under guardianship or safeguarding of justice
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
CHRU Amiens
Amiens, 80090
Denis Chatelain, Pr, 33+322088281, chatelain.denis@chu-amiens.fr
About this study
Formaldehyde is notably used as a tissue fixator in pathological anatomy. Despite its toxicity, it continues to be widely used because it is currently not substitutable. Some plants have shown their ability to absorb formaldehyde. The investigators would like to show if the installation of plants in the Anatomy and Cytology Department of the Amiens University Hospital reduces the exposure to formaldehyde of the staff of this department. After carrying out atmospheric and biological measurements the investigators will install 15 plants in both rooms where the staff is most exposed to formaldehyde : the macroscopy room and the reception room. The atmospheric and biological measurements will be redone after two months.
- Conditions
- Formaldehyde, Pathological Anatomy and Cytology
- Being tested
- Biological measurement of urinary formic acid, Plant installation
- Keywords
- formaldehyde, plants, pathological anatomy and cytology, remediation, purification, occupational exposure, occupational health, carcinogen
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Biological measurement of urinary formic acidBiological
Biological measurement of urinary formic acid
Plant installationOther
plant installation
| Study group | Role | What they receive |
|---|---|---|
| laboratory staff | Experimental | Before / after installation of plants Receives: Biological: Biological measurement of urinary formic acid; Other: Plant installation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Atmospheric formaldehyde concentration
Variation of Atmospheric measurement of formaldehyde between before and after plant installation
Measured: 2 months
Secondary outcomes (1)
Variation of urinary formic acid concentration
Variation of Biological measurement of urinary formic acid between before and after plant installation
Measured: 2 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Dec 2025
- Study start25 Sep 2024
- Primary completion31 Dec 2024
- Study completionMay 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for FormaldehydeStudies of the same condition, open and under way.
- More trials run by Centre Hospitalier Universitaire, AmiensThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire, Amiens
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07264504
- Sponsor's protocol ID
- PI2023_843_0095
- Acronym
- DETOXANAPATH
- Status last verified
- Dec 2025
- First submitted
- 6 May 2025
- Last updated
- 4 Dec 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Experimentation of Formaldehyde Purification by Plants in the Anatomy and Cytology Department
- ClinicalTrials.gov ID
- NCT07264504
- Acronym / sponsor ID
- DETOXANAPATH / PI2023_843_0095
- Conditions
- Formaldehyde, Pathological Anatomy and Cytology
- Keywords
- formaldehyde, plants, pathological anatomy and cytology, remediation, purification, occupational exposure, occupational health, carcinogen
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Centre Hospitalier Universitaire, AmiensUniversity, hospital or other
- Study start
- 25 Sep 2024 (actual)
- Primary completion
- 31 Dec 2024 (actual)
- Study completion
- May 2026 (estimated)
- First posted
- 4 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Formaldehyde is notably used as a tissue fixator in pathological anatomy. Despite its toxicity, it continues to be widely used because it is currently not substitutable. Some plants have shown their ability to absorb formaldehyde. The investigators would like to show if the installation of plants in the Anatomy and Cytology Department of the Amiens University Hospital reduces the exposure to formaldehyde of the staff of this department. After carrying out atmospheric and biological measurements the investigators will install 15 plants in both rooms where the staff is most exposed to formaldehyde : the macroscopy room and the reception room. The atmospheric and biological measurements will be redone after two months.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| laboratory staff | Experimental | Biological: Biological measurement of urinary formic acid, Other: Plant installationBefore / after installation of plants |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- To work in the Department of Pathological Anatomy and Cytology
- Adult (> 18 years old)
- Patient information and collection of non-opposition
Key exclusion criteria (2 listed)
- Pregnant woman
- Patients under guardianship or safeguarding of justice
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Biological measurement of urinary formic acidBiological measurement of urinary formic acid | Biological | laboratory staff |
| Plant installationplant installation | Other | laboratory staff |
Primary outcome
Atmospheric formaldehyde concentration
Time frame: 2 months
Variation of Atmospheric measurement of formaldehyde between before and after plant installation
1 secondary outcome
Variation of urinary formic acid concentration
Time frame: 2 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Dec 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Biological measurement of urinary formic acid and Plant installation in people with Formaldehyde and Pathological Anatomy and Cytology, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 4 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Denis CHATELAIN, Pr (33+32288281, chatelain.denis@chu-amiens.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Atmospheric formaldehyde concentration (time frame: 2 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Dec 2025.