Health Adult SubjectsCOMITEX-BSPPNCT07270627
French Military Firefighters to Assess Relationships Between Exposome and Health.
An observational study of Health Adult Subjects and Exposure Occupational, run by Direction Centrale du Service de Santé des Armées at 1 site in France.
Trial summary
The aim of the study is to describe professional exposures and health events among French military firefighters (both active-duty personnel and veterans) and identify potential relationships between the exposome (the total history of occupational and personal exposures) and health status in these populations. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Health Adult Subjects, Exposure Occupational, Health Behavior, Risky
- How many people
- 1,811 participants
- Where
- 1 siteFrance
- Study dates
- 1 Jan 2026to 30 Jun 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Active-duty personnel from Paris firefighters brigade as a whole. Veterans from Paris firefighters brigade with known email address.
Who may be able to join
- Active-duty or veteran military personnel from French Paris firefighter brigade.
- Aged at least 18.
- Not opposed to participate to the study
Who cannot join
- Opposition to participate
- veterans under legal protection
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Cohorte Militaire et Son Exposome : étude Pilote rétrospective au Sein de la Population Des Sapeurs-pompiers (Actuellement en Exercice et Anciens Sapeurs-pompiers) de la Brigade Des Sapeurs Pompiers de Paris
The aim of the study is to describe professional exposures and health events among French military firefighters (both active-duty personnel and veterans) and identify potential relationships between the exposome (the total history of occupational and personal exposures) and health status in these populations. The study is based on a self-administered questionnaire that collects retrospective and present information about exposures and health conditions.
Read the detailed description
This group of military personnel is professionally exposed, in the diversity of its activities (rescue of victims but also firefighting, protection of property, technological risks, traffic accidents, assistance to individuals, etc.), to multiple health risks, as specified in a report by ANSES (ANSES 2019):
- chemical and particulate substances (polycyclic aromatic hydrocarbons (PAHs) present in fire smoke in particular, asbestos, diesel emissions);
- biological agents (viruses, bacteria, mold, etc.) or physical agents (noise, ionizing or non-ionizing radiation such as electromagnetic fields, optical radiation, radioactivity, extreme temperatures and pressures, vibrations, etc.);
- organizational constraints (time constraints, intensity and pace of work) and psychosocial constraints, including exposure to violence.
Furthermore, in 2007, the International Agency for Research on Cancer (IARC) classified firefighting as "probably carcinogenic to humans" based on limited evidence of cancer in humans, particularly non-Hodgkin's lymphoma, prostate cancer, and testicular cancer (IARC 2007). In 2022, occupational exposure of firefighters was considered "carcinogenic to humans" based on sufficient evidence for mesothelioma and bladder cancer and limited evidence for colon, prostate, and testicular cancers, melanoma, and non-Hodgkin's lymphoma (IARC 2022, Senate 2024).
A study conducted within the BSPP would not only provide better documentation of the impact of the military firefighting profession on health, but also estimate the feasibility of such a study: participation and adherence rates to the cohort, acceptability of the inclusion questionnaire and the questions asked with feedback. The data collected in the questionnaires that accompany nationwide cohort studies are indeed substantial, with a wide variety of questions requiring memory recall. Consequently, the choice and structure of the questions asked are essential in order to minimize the amount of missing data (non-response bias) and maintain a satisfactory quality of data collection, thereby ensuring the internal and external validity of the results obtained. The study among active and former firefighters will thus validate the method chosen to include participants in the future general military cohort, as well as the initial questionnaire. At the end of the questionnaire, questions about the participants' experience will be asked in order to assess the acceptance and feasibility of a future study.
- Conditions
- Health Adult Subjects, Exposure Occupational, Health Behavior, Risky, Occupational Health, Exposure, Firefighters
- Keywords
- Occupational exposure, health, military, exposome, occupational
- Medical subject headings
- Health Risk Behaviors
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Active-duty firefighters (military) | Active-duty firefighters who will be considered several subgroups according exposure studied. | |
| Veteran firesoldiers | Veteran firesoldiers who will partitioned in several subgroups according exposure studied. |
What is being measured
The primary outcome is the main question the study is designed to answer.
To identify associations between occupational and environnment exposures and the health status reported by current and former military firefighters,
To identify associations between occupational and environnment exposures and the health status reported by current and former military firefighters, through difference in prevalence of the health events (muscoskelatal, psychologic, cardiovascular... ) studied between those exposed to one or more risk factors (chemical/ physical/ psychological) and those not exposed to these factors.
Measured: Period at enrollment in the study (from January 2026 to March 2026) of Health outcome (with retrospective assessment of exposure in the past as firefighter).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Dec 2025
- Study start1 Jan 2026
- Primary completion30 Jun 2026
- Study completion30 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Health Adult SubjectsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 1,811 participants (actual)
Sponsor and investigators
- Lead sponsor
- Direction Centrale du Service de Santé des Armées
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07270627
- Sponsor's protocol ID
- 2023PBMD02
- Acronym
- COMITEX-BSPP
- Status last verified
- Nov 2025
- First submitted
- 10 Sep 2025
- Last updated
- 28 Aug 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: (security and regulation)
Study at a glance
From the registry record, last updated by the sponsor on 28 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Cohorte Militaire et Son Exposome : étude Pilote rétrospective au Sein de la Population Des Sapeurs-pompiers (Actuellement en Exercice et Anciens Sapeurs-pompiers) de la Brigade Des Sapeurs Pompiers de Paris
- ClinicalTrials.gov ID
- NCT07270627
- Acronym / sponsor ID
- COMITEX-BSPP / 2023PBMD02
- Conditions
- Health Adult Subjects, Exposure Occupational, Health Behavior, Risky, Occupational Health, Exposure, Firefighters
- Keywords
- Occupational exposure, health, military, exposome, occupational
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 1,811 participants (actual)
- Lead sponsor
- Direction Centrale du Service de Santé des ArméesUniversity, hospital or other
- Collaborators
- Institut National de la Santé Et de la Recherche Médicale, France
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 30 Jun 2026 (actual)
- Study completion
- 30 Jun 2026 (actual)
- First posted
- 8 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of the study is to describe professional exposures and health events among French military firefighters (both active-duty personnel and veterans) and identify potential relationships between the exposome (the total history of occupational and personal exposures) and health status in these populations. The study is based on a self-administered questionnaire that collects retrospective and present information about exposures and health conditions.
Detailed description
This group of military personnel is professionally exposed, in the diversity of its activities (rescue of victims but also firefighting, protection of property, technological risks, traffic accidents, assistance to individuals, etc.), to multiple health risks, as specified in a report by ANSES (ANSES 2019):
- chemical and particulate substances (polycyclic aromatic hydrocarbons (PAHs) present in fire smoke in particular, asbestos, diesel emissions);
- biological agents (viruses, bacteria, mold, etc.) or physical agents (noise, ionizing or non-ionizing radiation such as electromagnetic fields, optical radiation, radioactivity, extreme temperatures and pressures, vibrations, etc.);
- organizational constraints (time constraints, intensity and pace of work) and psychosocial constraints, including exposure to violence.
Furthermore, in 2007, the International Agency for Research on Cancer (IARC) classified firefighting as "probably carcinogenic to humans" based on limited evidence of cancer in humans, particularly non-Hodgkin's lymphoma, prostate cancer, and testicular cancer (IARC 2007). In 2022, occupational exposure of firefighters was considered "carcinogenic to humans" based on sufficient evidence for mesothelioma and bladder cancer and limited evidence for colon, prostate, and testicular cancers, melanoma, and non-Hodgkin's lymphoma (IARC 2022, Senate 2024).
A study conducted within the BSPP would not only provide better documentation of the impact of the military firefighting profession on health, but also estimate the feasibility of such a study: participation and adherence rates to the cohort, acceptability of the inclusion questionnaire and the questions asked with feedback. The data collected in the questionnaires that accompany nationwide cohort studies are indeed substantial, with a wide variety of questions requiring memory recall. Consequently, the choice and structure of the questions asked are essential in order to minimize the amount of missing data (non-response bias) and maintain a satisfactory quality of data collection, thereby ensuring the internal and external validity of the results obtained. The study among active and former firefighters will thus validate the method chosen to include participants in the future general military cohort, as well as the initial questionnaire. At the end of the questionnaire, questions about the participants' experience will be asked in order to assess the acceptance and feasibility of a future study.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Active-duty firefighters (military) | – | –Active-duty firefighters who will be considered several subgroups according exposure studied. |
| Veteran firesoldiers | – | –Veteran firesoldiers who will partitioned in several subgroups according exposure studied. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Active-duty personnel from Paris firefighters brigade as a whole. Veterans from Paris firefighters brigade with known email address.
Key inclusion criteria (3 listed)
- Active-duty or veteran military personnel from French Paris firefighter brigade.
- Aged at least 18.
- Not opposed to participate to the study
Key exclusion criteria (2 listed)
- Opposition to participate
- veterans under legal protection
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
To identify associations between occupational and environnment exposures and the health status reported by current and former military firefighters,
Time frame: Period at enrollment in the study (from January 2026 to March 2026) of Health outcome (with retrospective assessment of exposure in the past as firefighter).
To identify associations between occupational and environnment exposures and the health status reported by current and former military firefighters, through difference in prevalence of the health events (muscoskelatal, psychologic, cardiovascular... ) studied between those exposed to one or more risk factors (chemical/ physical/ psychological) and those not exposed to these factors.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Aug 2026.
- Individual participant dataSharing planned: No. (security and regulation)
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Health Adult Subjects and Exposure Occupational, run by Direction Centrale du Service de Santé des Armées at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
To identify associations between occupational and environnment exposures and the health status reported by current and former military firefighters, (time frame: Period at enrollment in the study (from January 2026 to March 2026) of Health outcome (with retrospective assessment of exposure in the past as firefighter).). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Aug 2026.