Periodontal DiseaseNCT07271563
Assessment of Pentraxin Levels in the Gingival Fluid of Abutment Teeth in the Context of the Use of Fixed Dentures
An observational study of Periodontal Disease and Periodontal Diseases, run by Jagiellonian University at 1 site in Poland.
Trial summary
The use of fixed dentures in prosthetic treatment requires a thorough analysis of clinical factors such as: the condition of the abutments subject to grinding procedures, the degree of their loosening, the extent of missing teeth, and the condition of the periodontal tissues. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Periodontal Disease, Periodontal Diseases, Prosthodontics
- What is being tested?
- Diagnostic Pentraxine test
- How many people
- 90 participants
- Where
- 1 sitePoland
- Study dates
- 1 Mar 2023to 1 Aug 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: The study material consist of 90 patients, of both sexes, aged between 35-48 years, who report for prosthetic treatment with fixed dentures to the University Dental Clinic at the Institute of Dentistry in Krakow, in the period: March 2023- August 2024.
Who may be able to join
- appropriate age range of patients, indication for the use of fixed dentures, no signs of gingivitis in the clinical examination
Who cannot join
- any autoimmune disease or other systemic disease which could alter the course of periodontal disease, the desire to withdraw from participation in the research and the occurrence of general and local diseases
Trial locations and contacts
1 site in 1 country.
About this study
The use of fixed dentures in prosthetic treatment requires a thorough analysis of clinical factors such as: the condition of the abutments subject to grinding procedures, the degree of their loosening, the extent of missing teeth, and the condition of the periodontal tissues. An important step in prosthetic treatment is planning subsequent procedures, including the grinding of the crowns of the natural teeth. Often, the initial stages of gingivitis are not visible during a clinical examination [1-4].
- Conditions
- Periodontal Disease, Periodontal Diseases, Prosthodontics
- Being tested
- Diagnostic Pentraxine test
- Medical subject headings
- Periodontal Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Diagnostic Pentraxine testDiagnostic test
Diagnostic test - in order to measure Pantraxine level in gingival fluid was performed.
What is being measured
The primary outcome is the main question the study is designed to answer.
Concentration of pentraxine
Measured: March 2023- August 2024
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Dec 2025
- Study start1 Mar 2023
- Primary completion1 Aug 2024
- Study completion1 Aug 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Periodontal DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Retrospective
- Enrolment
- 90 participants (actual)
Sponsor and investigators
- Lead sponsor
- Jagiellonian University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Andrzej Gala, Jagiellonian University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07271563
- Sponsor's protocol ID
- 1072.6120.131.2023
- Status last verified
- Dec 2025
- First submitted
- 15 Nov 2025
- Last updated
- 9 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 9 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessment of Pentraxin Levels in the Gingival Fluid of Abutment Teeth in the Context of the Use of Fixed Dentures
- ClinicalTrials.gov ID
- NCT07271563
- Acronym / sponsor ID
- 1072.6120.131.2023
- Conditions
- Periodontal Disease, Periodontal Diseases, Prosthodontics
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 90 participants (actual)
- Lead sponsor
- Jagiellonian UniversityUniversity, hospital or other
- Study start
- 1 Mar 2023 (actual)
- Primary completion
- 1 Aug 2024 (actual)
- Study completion
- 1 Aug 2024 (actual)
- First posted
- 9 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The use of fixed dentures in prosthetic treatment requires a thorough analysis of clinical factors such as: the condition of the abutments subject to grinding procedures, the degree of their loosening, the extent of missing teeth, and the condition of the periodontal tissues. An important step in prosthetic treatment is planning subsequent procedures, including the grinding of the crowns of the natural teeth. Often, the initial stages of gingivitis are not visible during a clinical examination [1-4].
Study design
- Observational model
- Case-control
- Time perspective
- Retrospective
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- The study material consist of 90 patients, of both sexes, aged between 35-48 years, who report for prosthetic treatment with fixed dentures to the University Dental Clinic at the Institute of Dentistry in Krakow, in the period: March 2023- August 2024.
Key inclusion criteria (1 listed)
- appropriate age range of patients, indication for the use of fixed dentures, no signs of gingivitis in the clinical examination
Key exclusion criteria (1 listed)
- any autoimmune disease or other systemic disease which could alter the course of periodontal disease, the desire to withdraw from participation in the research and the occurrence of general and local diseases
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Diagnostic Pentraxine testDiagnostic test - in order to measure Pantraxine level in gingival fluid was performed. | Diagnostic test | – |
Primary outcome
Concentration of pentraxine
Time frame: March 2023- August 2024
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Dec 2025.
Related trials for Periodontal Disease
Not yet recruitingObservational study
Periodontal Status and Biomarkers in MASLD
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Recruiting
Thermosensitive Hyaluronic Gel With Octenidine as an Adjunctive to Subgingival Instrumentation
Periodontal Disease
Active, not recruitingObservational study
A Retrospective Comparative Evaluation of Omega-3 and Resveratrol Supplementation in Patients With Periodontitis
Periodontitis
Recruiting
Effects of Different Activation Techniques on Antimicrobial Photodynamic Therapy in Apical Periodontitis
Apical Periodontitis, Endodontic Retreatment
Recruiting
Ozone Gel Versus Chlorohexidine Gel as an Adjunct to Non-Surgical Treatment of Stage II Periodontitis Grade B Among Smokers Patients
Ozone Gel, Chlorohexidine Gel
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Periodontal Disease and Periodontal Diseases, run by Jagiellonian University at 1 site in Poland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Poland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Concentration of pentraxine (time frame: March 2023- August 2024). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Dec 2025.