StrokeNCT07272759
Feasibility Study of Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) Program Among People With Stroke in Bang
A study testing Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) Program in people with Stroke, run by Tokyo Metropolitan University at 1 site in Bangladesh.
Trial summary
Stroke causes major disability issues in Bangladesh and often leaves people unable to look after themselves, work, or participate in family and community life. Most stroke survivors in Bangladesh do not receive adequate rehabilitation, and existing services focus mainly on physical exercises, not on helping people… Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Stroke
- What is being tested?
- Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) Program
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 6 participants
- Where
- 1 siteBangladesh
- Study dates
- 20 Oct 2025to 30 Mar 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Aged 18-64 years,
- Diagnosed with stroke (ischemic/hemorrhagic) 3-24 months prior,
- Medically stable and able to provide informed consent,
- MoCA score ≥18.
Who cannot join
- Severe receptive aphasia,
- Major psychiatric disorders,
- Unstable medical conditions
Trial locations and contacts
1 site in 1 country.
Bangladesh1 site
Centre for the Rehabilitation of the Paralysed (CRP)
Dhaka
About this study
Stroke causes major disability issues in Bangladesh and often leaves people unable to look after themselves, work, or participate in family and community life. Most stroke survivors in Bangladesh do not receive adequate rehabilitation, and existing services focus mainly on physical exercises, not on helping people return to meaningful activities.
The REAP programme is a new therapy approach that remediates skills through structured training, educates patients and families on stroke management, adapts tasks or environments to make daily activities easier, and promotes participation in meaningful roles and activities.
This study will test whether the REAP programme can be delivered successfully in a Bangladeshi rehabilitation centre, whether patients find it acceptable, and whether it helps people become more independent and improves quality of life.
- Conditions
- Stroke
- Being tested
- Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) Program
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) ProgramOther
The REAP program consists of four core components designed to address the complex needs of stroke survivors:
- Remediation
- Education
- Adaptation
- Promotion
| Study group | Role | What they receive |
|---|---|---|
| Stroke patients who are taking rehabilitation | Experimental | Stroke patients aged 18-64 years, diagnosed with stroke (ischemic/hemorrhagic) 3-6 months prior, medically stable and able to provide informed consent, MoCA score ≥18. Receives: Other: Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) Program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Barthel Index
Assesses independence in activities of daily living (ADLs).
Measured: From enrollment to 12 weeks
Montreal Cognitive Assessment (MoCA)
Screens for cognitive impairment.
Measured: Enrollment to 12 weeks
Bangladeshi Occupational Self-Assessment - Short Form (BOSA-SF) (
Evaluates perceived occupational competence and values within the local context.
Measured: Enrollment to 12 weeks
Fugl-Meyer Assessment (FMA)
Assesses motor recovery post-stroke
Measured: Enrollment to 12 weeks
Occupational Balance Questionnaire
Measures balance between different occupational areas in everyday life.
Measured: Enrollment to 12 weeks
Life Satisfaction Questionnaire (LiSat-11)
Assesses subjective life satisfaction across various domains
Measured: Enrollment to 12 weeks
Zarit Caregiver Burden Scale
Assesses the level of burden experienced by informal caregivers
Measured: Enrollment to 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Dec 2025
- Study start20 Oct 2025
- Primary completion20 Dec 2025 (estimated)
- Study completion30 Mar 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 6 participants (actual)
Sponsor and investigators
- Lead sponsor
- Tokyo Metropolitan University
- Sponsor type
- University, hospital or other
- Collaborators
- Centre for the Rehabilitation of the Paralysed, Bangladesh
- Responsible party
- Principal investigator, Azharul Islam, Tokyo Metropolitan University
- Investigators
- Peter Bontje, PhD, Study director, Tokyo Metropolitan University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07272759
- Sponsor's protocol ID
- CRP-ERC-R&E-0401-0479
- Status last verified
- Nov 2025
- First submitted
- 26 Nov 2025
- Last updated
- 9 Dec 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 9 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Feasibility Study of Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) Program Among People With Stroke in Bang
- ClinicalTrials.gov ID
- NCT07272759
- Acronym / sponsor ID
- CRP-ERC-R&E-0401-0479
- Conditions
- Stroke
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 6 participants (actual)
- Lead sponsor
- Tokyo Metropolitan UniversityUniversity, hospital or other
- Collaborators
- Centre for the Rehabilitation of the Paralysed, Bangladesh
- Study start
- 20 Oct 2025 (actual)
- Primary completion
- 20 Dec 2025 (estimated)
- Study completion
- 30 Mar 2026 (estimated)
- First posted
- 9 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Stroke causes major disability issues in Bangladesh and often leaves people unable to look after themselves, work, or participate in family and community life. Most stroke survivors in Bangladesh do not receive adequate rehabilitation, and existing services focus mainly on physical exercises, not on helping people return to meaningful activities.
The REAP programme is a new therapy approach that remediates skills through structured training, educates patients and families on stroke management, adapts tasks or environments to make daily activities easier, and promotes participation in meaningful roles and activities.
This study will test whether the REAP programme can be delivered successfully in a Bangladeshi rehabilitation centre, whether patients find it acceptable, and whether it helps people become more independent and improves quality of life.
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Stroke patients who are taking rehabilitation | Experimental | Other: Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) ProgramStroke patients aged 18-64 years, diagnosed with stroke (ischemic/hemorrhagic) 3-6 months prior, medically stable and able to provide informed consent, MoCA score ≥18. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Aged 18-64 years,
- Diagnosed with stroke (ischemic/hemorrhagic) 3-24 months prior,
- Medically stable and able to provide informed consent,
- MoCA score ≥18.
Key exclusion criteria (3 listed)
- Severe receptive aphasia,
- Major psychiatric disorders,
- Unstable medical conditions
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) ProgramThe REAP program consists of four core components designed to address the complex needs of stroke survivors: 1. Remediation 2. Education 3. Adaptation 4. Promotion | Other | Stroke patients who are taking rehabilitation |
Primary outcome
Barthel Index
Time frame: From enrollment to 12 weeks
Assesses independence in activities of daily living (ADLs).
Montreal Cognitive Assessment (MoCA)
Time frame: Enrollment to 12 weeks
Screens for cognitive impairment.
Bangladeshi Occupational Self-Assessment - Short Form (BOSA-SF) (
Time frame: Enrollment to 12 weeks
Evaluates perceived occupational competence and values within the local context.
Fugl-Meyer Assessment (FMA)
Time frame: Enrollment to 12 weeks
Assesses motor recovery post-stroke
Occupational Balance Questionnaire
Time frame: Enrollment to 12 weeks
Measures balance between different occupational areas in everyday life.
Life Satisfaction Questionnaire (LiSat-11)
Time frame: Enrollment to 12 weeks
Assesses subjective life satisfaction across various domains
Zarit Caregiver Burden Scale
Time frame: Enrollment to 12 weeks
Assesses the level of burden experienced by informal caregivers
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Dec 2025.
Related trials for Stroke
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ELATE Study: Evaluating Large-vessel Acute Thrombectomy in Extended Time Window
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Web-Based Tele-Rehabilitation Using Action Observation and Mirror Therapy for Subacute Stroke: A Randomized Controlled Trial
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Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Peter Bontje, PhD study director
Tokyo Metropolitan University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) Program in people with Stroke, run by Tokyo Metropolitan University at 1 site in Bangladesh.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 9 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Bangladesh. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Barthel Index (time frame: From enrollment to 12 weeks). The study lists 7 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Dec 2025.