ABO IncompatibilityNCT07273448

Study on the Clinical Outcomes of ABO-Incompatible Living Donor Liver Transplantation

An observational study of ABO Incompatibility and Liver Transplant Surgery, run by Zhi-Jun Zhu.

Enrolling by invitation

Enrolling by invitation. The study team selects and invites participants, usually from an existing group of patients.

Official record

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Trial summary

Evaluate the postoperative survival rate and incidence of rejection in patients undergoing ABO-incompatible living donor liver transplantation; analyze the occurrence of secondary endpoint events such as postoperative vascular complications and biliary complications; and explore relevant risk factors affecting… Read more about this study

Who is it for?: Any age
Conditions the study is for: ABO Incompatibility, Liver Transplant Surgery, Living Donor Liver Transplantation
How many people: 100 participants
Where: No sites listed yet
Study dates: 1 Jan 2014to 31 Dec 2029
Phase: Observational

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages Any age
All sexes
No healthy volunteers
Child, Adult, Older adult

Study population: All eligible patients who underwent ABO-incompatible living donor liver transplantation between January 1, 2014 and December 31, 2028 and met the inclusion and exclusion criteria.

Who may be able to join

Underwent ABO-incompatible living donor liver transplantation
Complete and intact clinical and follow-up data

Who cannot join

Non-primary liver transplantation
Combined other organ transplantation
Incomplete clinical data or loss to follow-up

About this study

Read the detailed description

Prospective and retrospective

Conditions: ABO Incompatibility, Liver Transplant Surgery, Living Donor Liver Transplantation

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Study groups in NCT07273448
Study group	Role	What they receive
ABO-Incompatible Living Donor Liver Transplantation Patients		Evaluate the postoperative survival rate and incidence of rejection in patients undergoing ABO-incompatible living donor liver transplantation; analyze the occurrence of secondary endpoint events such as postoperative vascular complications and biliary complications; and explore relevant risk factors affecting prognosis.

What is being measured

The primary outcome is the main question the study is designed to answer.

Postoperative survival rate
Measured: Minimum follow-up period of 1 year postoperatively.
incidence of acute rejection
Measured: Within 1 year postoperatively

Secondary outcomes (2)

Vascular complications
Measured: Within 1 year postoperatively
Biliary complications
Measured: Within 1 year postoperatively

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1 Jan 201431 Dec 2029

First posted9 Dec 2025
Study start1 Jan 2014
Primary completion31 Dec 2028 (estimated)
Study completion31 Dec 2029 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for ABO IncompatibilityStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Observational
Observational model: Cohort
Time perspective: Other
Enrolment: 100 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07273448
Sponsor's protocol ID: BFH20251127006
Status last verified: Nov 2025
First submitted: 20 Nov 2025
Last updated: 20 May 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No