Anorexia NervosaPriCo-SCASANCT07274722
Influence of Control Deprivation on the Use of the Analytical Cognitive Style in Anorexic Subjects
A study of Anorexia Nervosa, run by Centre Hospitalier Henri Laborit at 1 site in France.
Trial summary
The use of an analytical cognitive style is a specific feature of anorexia nervosa and is thought to contribute to the maintenance of the disorder, in particular by encouraging fragmented body perception and a focus on certain parts of the body to the detriment of overall harmony and coherence. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Anorexia Nervosa
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 54 participants
- Where
- 1 siteFrance
- Study dates
- 4 Apr 2024to 3 Apr 2028
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Be undergoing treatment at Centre Hospitalier Laborit (CHL) or Centre Hospitalier Universitaire (CHU) de Poitiers for an Eating Disorder (ED) of the Anorexia Nervosa type.
- Patients must meet the diagnostic criteria for Anorexia Nervosa according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5; American Psychiatric Association, APA, 2013), or present a sub-clinical symptomatology requiring treatment:
- Restriction of energy intake relative to requirements, leading to a significantly low body weight, taking into account age, sex, developmental stage, and physical health; (B) Intense fear of gaining weight or becoming fat, or persistent behavior that interferes with weight gain, even when at a significantly low weight; (C) Disturbance in the way body weight or shape is experienced, undue influence of body weight or shape on self-esteem, or persistent lack of recognition of the seriousness of the current low body weight.
Who cannot join
- Objection of the referring therapist
- Currently receiving cognitive remediation targeting mental flexibility and central coherence
- Body Mass Index (BMI) less than 14
- Inability to understand instructions in French
- Visual impairment or dyslexia
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
Centre Hospitalier Henri Laborit
Poitiers, 86000
Nematollah Jaafari, Professor, +33 516 52 61 18, nemat.jaafari@ch-poitiers.fr
About this study
The use of an analytical cognitive style is a specific feature of anorexia nervosa and is thought to contribute to the maintenance of the disorder, in particular by encouraging fragmented body perception and a focus on certain parts of the body to the detriment of overall harmony and coherence. The need for control has also been described as an important element in the pathology. At the same time, some authors have shown that, outside of any pathology, recourse to the analytical cognitive style could respond to a need to restore control and, in turn, improve the feeling of control. However, at present, no causal relationship has been demonstrated between the feeling of loss of control and the analytical cognitive style in anorexia nervosa. However, such a relationship would enable us to gain a better understanding of the underlying mechanisms of the disorder and to better target the treatment of patients.
- Conditions
- Anorexia Nervosa
- Being tested
- Cognitive Control Deprivation Task
- Medical subject headings
- Anorexia Nervosa
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cognitive Control Deprivation TaskOther
The investigators will measure the reaction time to the detection of a stimulus requiring analytical information processing compared with the time required to detect a stimulus requiring global information processing. These measurements will be carried out before and after a cognitive control deprivation experiment, which will be used to activate a need for control in the experimental context. The two measures will then be compared to examine the changes that occur after the deprivation of control.
| Study group | Role | What they receive |
|---|---|---|
| Cognitive Control Deprivation | Experimental | Not described Receives: Other: Cognitive Control Deprivation Task |
What is being measured
The primary outcome is the main question the study is designed to answer.
Reaction time
Measured: Baseline (before cognitive control deprivation) and immediately post-task (after cognitive control deprivation on Day 1)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Dec 2025
- Study start4 Apr 2024
- Primary completion3 Apr 2028 (estimated)
- Study completion3 Apr 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anorexia NervosaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 54 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Henri Laborit
- Sponsor type
- University, hospital or other
- Collaborators
- Centre de Recherches sur la Cognition et l'Apprentissage
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07274722
- Sponsor's protocol ID
- 2023-A00826-39
- Acronym
- PriCo-SCASA
- Status last verified
- Oct 2026
- First submitted
- 3 Jun 2025
- Last updated
- 22 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No