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Piriformis SyndromeNCT07278193

Foam Rolling and Dynamic Stretching in Piriformis Syndrome

A study testing Group A (Foam Rolling) and Group B (Foam rolling and Dynamic Stretching) in people with Piriformis Syndrome, run by University of Lahore at 1 site in Pakistan.

Active, not recruiting

Under way, not looking for participants. Everyone needed has enrolled. The study is still running.

Official record
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Trial summary

To compare the combined effects of foam rolling and dynamic stretching in patients with piriformis syndrome. 1. Warm-Up (2-3 minutes) Objective: Increase blood flow and prepare muscles for stretching. Marching in Place - 30 seconds Pelvic Tilts - 10 reps Gentle Hip Circles - 10 reps each direction 2. Read more about this study

Who is it for?
Ages 35 to 50 years
Conditions the study is for
Piriformis Syndrome
What is being tested?
Group A (Foam Rolling) and Group B (Foam rolling and Dynamic Stretching)
Could I receive a placebo?
No, everyone receives an active treatment
How many people
40 participants
Where
1 sitePakistan
Study dates
31 Oct 2025to 2 Jan 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 35 to 50 years
  • All sexes
  • No healthy volunteers
  • Adult

Who may be able to join

  • Age 35-50 years diagnosed with Piriformis Syndrome based on clinical findings. (Chang et al., 2024)
  • Having positive FAIR test is commonly used to diagnose piriformis syndrome.
  • Pain intensity of at least 4 on the numeric pain rating scale (NPRS) at baseline(A Penichet-Tomas et al., 2021).
  • DIAGNOSTIC CRITERIA OF PIRIFORMIS SYNDROME
  • The diagnostic criteria for piriformis syndrome include clinical history, physical examination findings. The symptoms include buttock pain radiating to the posterior thigh or leg, worsened by sitting, climbing stairs, or activities that stretch the piriformis muscle. Physical examination, tenderness over the piriformis muscle or sciatic notch and a positive FAIR test (Flexion, Adduction, and Internal Rotation) are indicative. Additional tests, such as the Pace test and Straight Leg Raise with external rotation.

Who cannot join

  • Current use of medications such as strong analgesics or muscle relaxants. (e.g., injections, surgery) within the last three months.
  • Uncontrolled medical conditions, such as active infections, cancer, or cardiovascular issues that may interfere with the study or the participant's ability to complete the protocol safely(Alfonso Penichet-Tomas et al., 2021).
  • History of lumbar disc herniation, spinal stenosis, or other serious lumbar spine pathologies that may cause similar symptoms.
  • Prior surgeries in the lumbar spine, hip, or pelvis that may interfere with the study's outcomes(Pişirici et al., 2020).

Trial locations and contacts

1 site in 1 country.

Pakistan1 site
  • University of Lahore teaching hospital

    Lahore, Punjab Province, 54000

Other trials in Pakistan

About this study

Official title: Combined Effects of Foam Rolling and Dynamic Stretching in Patients With Piriformis Syndrome

To compare the combined effects of foam rolling and dynamic stretching in patients with piriformis syndrome.

  1. Warm-Up (2-3 minutes) Objective: Increase blood flow and prepare muscles for stretching.
Read more
  • Marching in Place - 30 seconds
  • Pelvic Tilts - 10 reps
  • Gentle Hip Circles - 10 reps each direction
  1. Intervention Phase (8-10 minutes) Group 1: Foam Rolling Alone (FR) (~10 minutes)
  • Piriformis Foam Rolling: 30-60 sec per side (2-3 sets)
  • Glutes \& Lower Back Foam Rolling: 30 sec each (2-3 sets)
  • Hamstrings \& IT Band Foam Rolling: 30 sec each (2-3 sets) Focus: Slow, controlled rolling with sustained pressure on tender spots. Group 2: Foam Rolling + Dynamic Stretching (FR+DS) (~10-12 minutes) Step 1: Foam Rolling (~5-6 minutes, same as Group 1) Step 2: Dynamic Stretching (~5-6 minutes)
  • Dynamic Piriformis Stretch: Standing knee-to-opposite-shoulder pull (10 reps per leg)
  • Leg Swings: Forward and sideways (10 reps each leg)
  • Walking Lunges with Rotation: 10 reps per leg
  • Hip Circles \& Controlled Butt Kicks: 10 reps each
  1. Cool-Down (2-3 minutes) Objective: Reduce muscle tension and promote recovery.
  • Seated Piriformis Stretch: 30 sec hold per side (2 sets)
  • Hamstring Stretch: 30 sec hold per leg
  • Lower Back Stretch (Child's Pose): 30 sec

Progression \& Adjustments

  • Gradual increase in duration or intensity as tolerated.
  • Modify exercises if discomfort or pain occurs.
  • After week 4, increase dynamic stretch duration if flexibility improves.

Outcome Measures

The effectiveness of the intervention will be assessed through the following key outcome measures:

  1. Pain Level - Evaluating changes in discomfort intensity during daily activities and movement.
  2. Range of Motion (ROM) - Measuring improvements in hip flexibility and mobility.
Read the detailed description

To compare the combined effects of foam rolling and dynamic stretching in patients with piriformis syndrome.

Inclusion Criteria:

  • Age 35-50 years diagnosed with Piriformis Syndrome based on clinical findings. (Chang et al., 2024)
  • Having positive FAIR test is commonly used to diagnose piriformis syndrome.
  • Pain intensity of at least 4 on the numeric pain rating scale (NPRS) at baseline(A Penichet-Tomas et al., 2021).

DIAGNOSTIC CRITERIA OF PIRIFORMIS SYNDROME

The diagnostic criteria for piriformis syndrome include clinical history, physical examination findings. The symptoms include buttock pain radiating to the posterior thigh or leg, worsened by sitting, climbing stairs, or activities that stretch the piriformis muscle. Physical examination, tenderness over the piriformis muscle or sciatic notch and a positive FAIR test (Flexion, Adduction, and Internal Rotation) are indicative. Additional tests, such as the Pace test and Straight Leg Raise with external rotation.

Exclusion Criteria:

  • Current use of medications such as strong analgesics or muscle relaxants. (e.g., injections, surgery) within the last three months.
  • Uncontrolled medical conditions, such as active infections, cancer, or cardiovascular issues that may interfere with the study or the participant's ability to complete the protocol safely(Alfonso Penichet-Tomas et al., 2021).
  • History of lumbar disc herniation, spinal stenosis, or other serious lumbar spine pathologies that may cause similar symptoms.
  • Prior surgeries in the lumbar spine, hip, or pelvis that may interfere with the study's outcomes(Pişirici et al., 2020).
  • ASSESMENT TOOL
  • Pain (NPRS): Pain will be measured using the NPRS (Numeric pain rating scale) which assesses the intensity of pain on a scale ranging from 0 no pain to 10 worst imaginable pain. Participants will report their pain levels at baseline and post-intervention to determine the efficacy of foam rolling and dynamic stretching.
  • ROM (Goniometer):The piriformis muscle plays a crucial role in hip movement and stabilization. Its primary function is external rotation of the hip with a normal range of motion (ROM) of 0°-45°. Additionally, the piriformis assists in hip abduction with a typical range of 0°-45°. Interestingly, the piriformis also supports internal rotation with a normal ROM of 0°-35°. These movements are assessed using a goniometer to measure hip rotation, where improvements in internal and external rotation, as well as abduction ROM, indicate reduced piriformis tightness and enhanced hip flexibility
  • SF-12 (QoL): The SF-12 (Short Form Health Survey) is a validated tool used to assess quality of life (QoL) across physical and mental health domains. It provides a concise yet comprehensive evaluation of functional limitations, pain, and overall well-being. Among individuals with piriformis syndrome, SF-12 can effectively measure the impact of pain and muscle tightness on daily activities and mental health.

Randomization: Randomization will be performed using a computer-generated method, ensuring that participants are randomly assigned to both groups. This process will minimize bias, and then half of the data will be allocated to each group for analysis.

Treatment Plan

Group A (Foam Rolling): Participants will use a foam roller to apply pressure to the piriformis muscle and surrounding areas, targeting tight spots and trigger points. This technique helps release muscle tension, improve blood circulation, and alleviate pain by using slow, controlled rolling motions that will last 5-10 minutes twice daily, 3 sessions per week for up to 8 weeks.

Group B (Foam rolling and Dynamic Stretching): Group B will receive foam rolling with dynamic stretching. Hot pack will be applied 5-3 min before rolling and dynamic stretching. The rolling helps release muscle tension, improve blood circulation, and alleviate pain by using slow, controlled rolling motions will last 5-10 minutes. The stretching routine will include exercises like hip swings, seated piriformis stretches, and Dynamic Figure-Four Stretch supine stretch. Each stretching session will last 10-15 minutes and will be conducted twice daily (3 days a week) for 8 weeks. This approach ensures gradual improvement in muscle flexibility and joint mobility while maintaining participant safety and comfort throughout the intervention. Ultrasound therapy will be applied after stretching.

Routine Physical Therapy

Duration: 8 weeks Frequency: Twice daily, 3 days a week Session Duration: 10-15 minutes per session

Being tested
Group A (Foam Rolling), Group B (Foam rolling and Dynamic Stretching)
Keywords
foam rolling, dynamic stretching, piriformis muscle, Quality of life
Medical subject headings
Piriformis Muscle Syndrome

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Group A (Foam Rolling)Other

    Foam Rolling Alone (FR) (~10 minutes)

    • Piriformis Foam Rolling: 30-60 sec per side (2-3 sets)
    • Glutes \& Lower Back Foam Rolling: 30 sec each (2-3 sets)
    • Hamstrings \& IT Band Foam Rolling: 30 sec each (2-3 sets) Focus: Slow, controlled rolling with sustained pressure on tender spots.
  • Group B (Foam rolling and Dynamic Stretching)Other

    Dynamic Stretching (~5-6 minutes)

    • Dynamic Piriformis Stretch: Standing knee-to-opposite-shoulder pull (10 reps per leg)
    • Leg Swings: Forward and sideways (10 reps each leg)
    • Walking Lunges with Rotation: 10 reps per leg
    • Hip Circles \& Controlled Butt Kicks: 10 reps each
    1. Cool-Down (2-3 minutes) Objective: Reduce muscle tension and promote recovery.
    • Seated Piriformis Stretch: 30 sec hold per side (2 sets)
    • Hamstring Stretch: 30 sec hold per leg
    • Lower Back Stretch (Child's Pose): 30 sec
Study groups in NCT07278193
Study groupRoleWhat they receive
Group A (Foam Rolling):ExperimentalParticipants will use a foam roller to apply pressure to the piriformis muscle and surrounding areas, targeting tight spots and trigger points. This technique helps release muscle tension, improve blood circulation, and alleviate pain by using slow, controlled rolling motions that will last 5-10 minutes twice daily, 3 sessions per week for up to 8 weeks.
Receives: Other: Group A (Foam Rolling)
Group B (Foam rolling and Dynamic Stretching)ExperimentalGroup B (Foam rolling and Dynamic Stretching): Group B will receive foam rolling with dynamic stretching. Hot pack will be applied 5-3 min before rolling and dynamic stretching. The rolling helps release muscle tension, improve blood circulation, and alleviate pain by using slow, controlled rolling motions will last 5-10 minutes. The stretching routine will include exercises like hip swings, seated piriformis stretches, and Dynamic Figure-Four Stretch supine stretch. Each stretching session will last 10-15 minutes and will be conducted twice daily (3 days a week) for 8 weeks. This approach ensures gradual improvement in muscle flexibility and joint mobility while maintaining participant safety and comfort throughout the intervention. Ultrasound therapy will be applied after stretching.
Receives: Other: Group B (Foam rolling and Dynamic Stretching)

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Goniometer

    Range of motion will be measured using the Goniometer. Its primary function is external rotation of the hip with a normal range of motion (ROM) of 0°- 45°additionally, the piriformis assists in hip abduction with a typical range of 0°-45°. Interestingly, the piriformis also supports internal rotation with a normal ROM of 0°-35°.

    Measured: At baseline, 4th week and 8th week

  2. NPRS (Numeric pain rating scale)

    Pain will be measured using the NPRS (Numeric pain rating scale) which assesses the intensity of pain on a scale ranging from 0 no pain to 10 worst imaginable pain. Participants will report their pain levels at baseline and post-intervention to determine the efficacy of foam rolling and dynamic stretching

    Measured: Each outcome variable will be measured at baseline, mid-intervention and post-intervention

Secondary outcomes (1)
  1. SF-12 (Short Form Health Survey)

    The SF-12 (Short Form Health Survey) is a validated tool used to assess quality of life (QoL) across physical and mental health domains. It provides a concise yet comprehensive evaluation of functional limitations, pain, and overall well-being. Among individuals with piriformis syndrome, SF-12 can effectively measure the impact of pain and muscle tightness on daily activities and mental health (Zhou et al., 2024).

    Measured: At baseline, 4th week and 8th week

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted11 Dec 2025
  2. Study start31 Oct 2025
  3. Primary completion25 Dec 2025 (estimated)
  4. Study completion2 Jan 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Model description
Model Description
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
40 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07278193
Sponsor's protocol ID
UOL/IREB/25/09/0047
Status last verified
Nov 2025
First submitted
30 Nov 2025
Last updated
11 Dec 2025
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing Group A (Foam Rolling) and Group B (Foam rolling and Dynamic Stretching) in people with Piriformis Syndrome, run by University of Lahore at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: under way, not looking for participants, as of the sponsor's last update on 11 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Goniometer (time frame: At baseline, 4th week and 8th week). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Dec 2025.

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