Intraoperative Lung Protective VentilationIOLPVCZNCT07282899
Intraoperative Lung Protective Ventilation in Czech Republic
An observational study of Intraoperative Lung Protective Ventilation, run by Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s..
Trial summary
This questionnaire-based study aims to evaluate the adherence to and current clinical practices regarding intraoperative lung-protective ventilation (IOLPV) among anesthesiologists in the Czech Republic. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Intraoperative Lung Protective Ventilation
- How many people
- 800 participants
- Where
- No sites listed yet
- Study dates
- 1 Feb 2026to 1 Aug 2026
- How long will I take part?
- 20 Days
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Anaesthesiologists in Czech republic
Who may be able to join
- anaesthesiologist practiting in Czech republic
Who cannot join
- not lincensed anaesthesiologist
- anaesthesiologist outside Czech republic
About this study
Official title: Overview of Intraoperative Lung Protective Ventilation in Czech Republic
This questionnaire-based study aims to evaluate the adherence to and current clinical practices regarding intraoperative lung-protective ventilation (IOLPV) among anesthesiologists in the Czech Republic. Despite the established role of IOLPV in reducing postoperative pulmonary complications in selected populations, its routine application during general anesthesia for elective surgeries remains variable. The survey focuses on identifying common ventilation strategies, attitudes toward lung recruitment maneuvers, tidal volume selection, use of PEEP, and awareness of existing recommendations. The results will provide insight into national practice patterns, perceived barriers, and educational needs, helping to inform future guidelines, training initiatives, and efforts to enhance patient safety and postoperative outcomes across Czech anesthesia departments.
Read the detailed description
This study is designed as an observational cross-sectional survey focusing on attitudes, knowledge, and practical application of intraoperative lung-protective ventilation among anesthesiology professionals in the Czech Republic. The primary aim is to describe the prevalence of LPV-related practices during general anesthesia in adult surgical patients. Key elements of LPV include the use of lower tidal volumes adjusted to predicted body weight, titrated PEEP, avoidance of unnecessary high oxygen fractions, and a judicious approach to lung recruitment maneuvers. The study evaluates whether these components are routinely utilized and if so, under what clinical circumstances.
Secondary aims of the study include identifying barriers that may prevent anesthesiologists from applying LPV techniques, such as concerns about hemodynamic instability, limited training, lack of standardized protocols, insufficient monitoring capabilities, or doubts regarding clinical benefit. The survey also investigates how clinicians perceive the safety of recruitment maneuvers and whether they encounter adverse effects such as hypotension, desaturation, or barotrauma. The survey explores whether respondents view LPV as universally beneficial or applicable only to specific patient groups such as obese or critically ill individuals. The study further investigates whether national or departmental protocols and guidelines for ventilation exist at respondents' workplaces, whether ventilator settings are standardized, and whether institutional education or quality improvement initiatives support evidence-based ventilation.
The target population consists of anesthesiologists and anesthesiology trainees actively involved in perioperative care in hospitals across the Czech Republic. Participation is voluntary and anonymous, with no patient-level data collected. Demographic information such as level of training, years of experience, type of institution, and exposure to specialized perioperative or intensive care practice is included to allow subgroup comparisons. Data collection is conducted online via a secure electronic questionnaire with an estimated completion time of approximately five to eight minutes. The distribution strategy includes professional organizations, departmental mailing lists, and professional association communication channels to maximize nationwide representation.
The study utilizes a structured questionnaire composed of multiple-choice and ordinal-scale items that address five thematic categories: general anesthetic ventilation practices including tidal volume and FiO₂ selection; PEEP use and adherence to recommendations; indications and frequency of recruitment maneuvers; perceived safety and complications associated with LPV; and institutional culture, including guideline availability and ventilator technology. Respondents are asked to report how they usually manage typical elective surgical cases rather than unusual or high-risk scenarios, allowing insight into real-world standard practices. The results will quantify how closely routine clinical practice aligns with currently available scientific evidence and international perioperative ventilation recommendations.
The primary outcome is the proportion of respondents reporting ventilation settings that meet predefined LPV criteria in their routine practice. Secondary outcomes include differences in adherence between trainee and consultant anesthesiologists, between academic and non-academic hospitals, between centers with and without formal local protocols, and between clinicians with differing exposure to intensive care medicine. The data will be analyzed descriptively and comparatively to identify significant trends or variability within the national practice environment. Findings from this survey may provide a basis for future interventional or educational studies and facilitate development of nationwide recommendations.
The study is conducted in accordance with ethical research principles, including the Declaration of Helsinki and relevant European data protection regulations. Ethical approval is being obtained prior to survey initiation. Participation is fully voluntary, and no identifying personal data are collected; responses are recorded and analyzed only in aggregated form. No clinical intervention is performed, and therefore no additional risks to patients or participants are expected. The expected benefits of this research include improved understanding of current perioperative respiratory practices and identification of potential gaps where updated knowledge translation or institutional support may be necessary.
The overall purpose of this project is to contribute to improving perioperative patient outcomes by strengthening evidence-based ventilation strategies during general anesthesia. By highlighting current practice and potential challenges in implementation, the results can support targeted educational efforts, standardized national recommendations, and greater awareness of intraoperative pulmonary protection among Czech anesthesia providers. The data will also help position Czech clinical practice within the broader European context and may encourage future collaborative research initiatives focused on postoperative pulmonary complication reduction and enhanced quality of anesthesia care.
- Keywords
- general anaesthesia, intraoperative lung protective ventilation
What is being measured
The primary outcome is the main question the study is designed to answer.
Adherence to IOLPV
Number of respondents that respond that meet IOLPV guidelines
Measured: 20 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Dec 2025
- Study start1 Feb 2026 (estimated)
- Primary completion1 Jul 2026 (estimated)
- Study completion1 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Intraoperative Lung Protective VentilationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 800 participants (estimated)
- Target duration
- 20 Days
Sponsor and investigators
- Lead sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Michal Kalina, Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07282899
- Sponsor's protocol ID
- IOLPVCZ
- Acronym
- IOLPVCZ
- Status last verified
- Dec 2025
- First submitted
- 2 Dec 2025
- Last updated
- 15 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: IPD will be shared through research office of the main department of the principal investigator on reasonable request.
Study at a glance
From the registry record, last updated by the sponsor on 15 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Overview of Intraoperative Lung Protective Ventilation in Czech Republic
- ClinicalTrials.gov ID
- NCT07282899
- Acronym / sponsor ID
- IOLPVCZ / IOLPVCZ
- Keywords
- general anaesthesia, intraoperative lung protective ventilation
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 800 participants (estimated)
- Lead sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.University, hospital or other
- Study start
- 1 Feb 2026 (estimated)
- Primary completion
- 1 Jul 2026 (estimated)
- Study completion
- 1 Aug 2026 (estimated)
- First posted
- 15 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This questionnaire-based study aims to evaluate the adherence to and current clinical practices regarding intraoperative lung-protective ventilation (IOLPV) among anesthesiologists in the Czech Republic. Despite the established role of IOLPV in reducing postoperative pulmonary complications in selected populations, its routine application during general anesthesia for elective surgeries remains variable. The survey focuses on identifying common ventilation strategies, attitudes toward lung recruitment maneuvers, tidal volume selection, use of PEEP, and awareness of existing recommendations. The results will provide insight into national practice patterns, perceived barriers, and educational needs, helping to inform future guidelines, training initiatives, and efforts to enhance patient safety and postoperative outcomes across Czech anesthesia departments.
Detailed description
This study is designed as an observational cross-sectional survey focusing on attitudes, knowledge, and practical application of intraoperative lung-protective ventilation among anesthesiology professionals in the Czech Republic. The primary aim is to describe the prevalence of LPV-related practices during general anesthesia in adult surgical patients. Key elements of LPV include the use of lower tidal volumes adjusted to predicted body weight, titrated PEEP, avoidance of unnecessary high oxygen fractions, and a judicious approach to lung recruitment maneuvers. The study evaluates whether these components are routinely utilized and if so, under what clinical circumstances.
Secondary aims of the study include identifying barriers that may prevent anesthesiologists from applying LPV techniques, such as concerns about hemodynamic instability, limited training, lack of standardized protocols, insufficient monitoring capabilities, or doubts regarding clinical benefit. The survey also investigates how clinicians perceive the safety of recruitment maneuvers and whether they encounter adverse effects such as hypotension, desaturation, or barotrauma. The survey explores whether respondents view LPV as universally beneficial or applicable only to specific patient groups such as obese or critically ill individuals. The study further investigates whether national or departmental protocols and guidelines for ventilation exist at respondents' workplaces, whether ventilator settings are standardized, and whether institutional education or quality improvement initiatives support evidence-based ventilation.
The target population consists of anesthesiologists and anesthesiology trainees actively involved in perioperative care in hospitals across the Czech Republic. Participation is voluntary and anonymous, with no patient-level data collected. Demographic information such as level of training, years of experience, type of institution, and exposure to specialized perioperative or intensive care practice is included to allow subgroup comparisons. Data collection is conducted online via a secure electronic questionnaire with an estimated completion time of approximately five to eight minutes. The distribution strategy includes professional organizations, departmental mailing lists, and professional association communication channels to maximize nationwide representation.
The study utilizes a structured questionnaire composed of multiple-choice and ordinal-scale items that address five thematic categories: general anesthetic ventilation practices including tidal volume and FiO₂ selection; PEEP use and adherence to recommendations; indications and frequency of recruitment maneuvers; perceived safety and complications associated with LPV; and institutional culture, including guideline availability and ventilator technology. Respondents are asked to report how they usually manage typical elective surgical cases rather than unusual or high-risk scenarios, allowing insight into real-world standard practices. The results will quantify how closely routine clinical practice aligns with currently available scientific evidence and international perioperative ventilation recommendations.
The primary outcome is the proportion of respondents reporting ventilation settings that meet predefined LPV criteria in their routine practice. Secondary outcomes include differences in adherence between trainee and consultant anesthesiologists, between academic and non-academic hospitals, between centers with and without formal local protocols, and between clinicians with differing exposure to intensive care medicine. The data will be analyzed descriptively and comparatively to identify significant trends or variability within the national practice environment. Findings from this survey may provide a basis for future interventional or educational studies and facilitate development of nationwide recommendations.
The study is conducted in accordance with ethical research principles, including the Declaration of Helsinki and relevant European data protection regulations. Ethical approval is being obtained prior to survey initiation. Participation is fully voluntary, and no identifying personal data are collected; responses are recorded and analyzed only in aggregated form. No clinical intervention is performed, and therefore no additional risks to patients or participants are expected. The expected benefits of this research include improved understanding of current perioperative respiratory practices and identification of potential gaps where updated knowledge translation or institutional support may be necessary.
The overall purpose of this project is to contribute to improving perioperative patient outcomes by strengthening evidence-based ventilation strategies during general anesthesia. By highlighting current practice and potential challenges in implementation, the results can support targeted educational efforts, standardized national recommendations, and greater awareness of intraoperative pulmonary protection among Czech anesthesia providers. The data will also help position Czech clinical practice within the broader European context and may encourage future collaborative research initiatives focused on postoperative pulmonary complication reduction and enhanced quality of anesthesia care.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 20 Days
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Anaesthesiologists in Czech republic
Key inclusion criteria (1 listed)
- anaesthesiologist practiting in Czech republic
Key exclusion criteria (2 listed)
- not lincensed anaesthesiologist
- anaesthesiologist outside Czech republic
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Adherence to IOLPV
Time frame: 20 days
Number of respondents that respond that meet IOLPV guidelines
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Dec 2025.
- Individual participant dataSharing planned: Yes. IPD will be shared through research office of the main department of the principal investigator on reasonable request.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Intraoperative Lung Protective Ventilation, run by Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s..
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 15 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Adherence to IOLPV (time frame: 20 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Dec 2025; AzTrials last refreshed its copy on 31 Oct 2026.