Glycaemic Response MeasurementsNCT07286981
Glycemic Index of Date Cultivars and Date-based Products
A study testing Date Cultivars and Date-based Products in people with Glycaemic Response Measurements, run by King Saud University at 1 site in Saudi Arabia.
Trial summary
Dates are widely consumed worldwide and hold substantial cultural importance in many Middle Eastern communities. Despite growing interest in measuring the glycemic response and glycemic index of foods for both research and practical applications, studies examining the glycemic properties of different date cultivars… Read more about this study
- Who is it for?
- Ages 18 to 55 yearsHealthy volunteers can take part
- Conditions the study is for
- Glycaemic Response Measurements
- What is being tested?
- Date Cultivars and Date-based Products
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteSaudi Arabia
- Study dates
- 16 Aug 2024to 25 May 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 55 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy adults aged 18 to 55 years
- Normotensive (normal blood pressure)
- Normal fasting glucose levels
- Not taking any prescription medication
- Able and willing to provide written informed consent
Who cannot join
- Morbid obesity (BMI > 40 kg/m²)
- Pre-diabetic status
- Pregnancy
- Any gastrointestinal disorders
- History of gastroenteritis within the preceding six months
- Previous gastrointestinal surgeries
Show all 9Show fewer
- Smoking
- Presence of chronic conditions (e.g., asthma, rheumatoid arthritis)
- Presence of acute illnesses (e.g., respiratory or urinary tract infections)
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Assessment of the Glycemic Index of Various Saudi Date Cultivars and Date-based Products. in Healthy Adults
Dates are widely consumed worldwide and hold substantial cultural importance in many Middle Eastern communities. Despite growing interest in measuring the glycemic response and glycemic index of foods for both research and practical applications, studies examining the glycemic properties of different date cultivars and their derived products remain limited. This study aims to determine the glycemic index (GI) and glycemic load (GL) of commonly consumed Saudi date cultivars and their derived products in healthy subjects, and to evaluate their potential impact on postprandial glucose responses. The study will consist of 4 phases as follows: phase 1: Date varieties at Tamer stage; phase 2: date varieties at Rutab stage; phase 3: Date's debs; phase 4: Date's paste. For each phase, ten subjects will be asked to attend the laboratory in the morning after an overnight fast on several occasions. Each visit will be separated from the next by a "washout" day. The reference food, 50 g of glucose dissolve in 250 ml water will be tested on 3 alternating days to diminish day to day variation of glucose tolerance. 50g equivalent carbohydrates of dates will be consumed with 250 ml of water. Participants will be blinded to the type of the dates. Glucose will be measured in capillary blood samples following the two hours of the test meal consumption, at 15 min interval (0, 15, 30, 45, 60, 90 and 120 min) . A qualified technician will perform all blood glucose measurements.
- Conditions
- Glycaemic Response Measurements
- Being tested
- Date Cultivars and Date-based Products
- Keywords
- glycemic index, Glycemic load, Dates, Tamer, Rutab, Date paste, Date molasses
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Date Cultivars and Date-based ProductsOther
Also called Tamer, Rutab, Date paste, Date molasses
Participants will consume 50 g of available carbohydrates from each date or date-based product, including 13 Tamer varieties, 12 Rutab varieties, 3 types of date paste, and 3 types of date molasses. Each product will be tested in a separate session.. The intervention will also include consumption of a glucose reference solution (50 g glucose) on three separate occasions.
| Study group | Role | What they receive |
|---|---|---|
| Single Group - Crossover Consumption of Date Products and Glucose Reference | Experimental | All participants will receive the glucose reference solution on three separate occasions and will consume the date or date-based product in individual sessions. Participants serve as their own control in a crossover design. Capillary blood glucose will be measured at several time points (0-120 minutes) after consumption to assess the glycemic index and load for each product. Receives: Other: Date Cultivars and Date-based Products |
What is being measured
The primary outcome is the main question the study is designed to answer.
Glycemic Index
The glycemic index of each date cultivar and date-based product will be determined on designated test days by calculating the incremental area under the blood glucose response curve (iAUC) over the 120-minute postprandial period following consumption of a portion containing 50 g of available carbohydrates, relative to the iAUC of a reference glucose solution. Blood glucose measurements will be obtained at baseline (fasting) and at predefined time points up to 120 minutes after ingestion.
Measured: Baseline (fasting) and up to 120 minutes post-consumption on each test day.
Secondary outcomes (1)
Glycemic Load (GL) of Fresh and Processed Date Products
The glycemic load of each date-based product will be calculated on each test day using the measured glycemic index and the available carbohydrate content of a typical serving, based on blood glucose measurements obtained at baseline and up to 120 minutes post-consumption.
Measured: Baseline (fasting) and up to 120 minutes post-consumption on each test day.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Dec 2025
- Study start16 Aug 2024
- Primary completion25 May 2025
- Study completion25 May 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Glycaemic Response MeasurementsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- This is a randomized crossover interventional study, where each participant serves as his or her own control. All volunteers consume the reference glucose solution on three occasions and then consume each date product in separate sessions. After each test food, blood glucose is measured repeatedly over 120 minutes to determine the postprandial responses and subsequently calculate the glycemic index and glycemic load.
- Masking
- None (open label)
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- King Saud University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Maha Alhussain, King Saud University
- Investigators
- Maha Alhussain, PhD, Study director, King Saud University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07286981
- Sponsor's protocol ID
- 24/1428
- Status last verified
- May 2025
- First submitted
- 3 Dec 2025
- Last updated
- 31 Dec 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Notably, individual participant data will not be shared to ensure the privacy and confidentiality of the study participants. The data includes personal health information and making them publicly available might risk the identification of participants despite efforts to anonymize them.
Publications
Brouns F, Bjorck I, Frayn KN, Gibbs AL, Lang V, Slama G, Wolever TM. Glycaemic index methodology. Nutr Res Rev. 2005 Jun;18(1):145-71. doi: 10.1079/NRR2005100.
PubMed 19079901
Study at a glance
From the registry record, last updated by the sponsor on 31 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessment of the Glycemic Index of Various Saudi Date Cultivars and Date-based Products. in Healthy Adults
- ClinicalTrials.gov ID
- NCT07286981
- Acronym / sponsor ID
- 24/1428
- Conditions
- Glycaemic Response Measurements
- Keywords
- glycemic index, Glycemic load, Dates, Tamer, Rutab, Date paste, Date molasses
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- King Saud UniversityUniversity, hospital or other
- Study start
- 16 Aug 2024 (actual)
- Primary completion
- 25 May 2025 (actual)
- Study completion
- 25 May 2025 (actual)
- First posted
- 16 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Dates are widely consumed worldwide and hold substantial cultural importance in many Middle Eastern communities. Despite growing interest in measuring the glycemic response and glycemic index of foods for both research and practical applications, studies examining the glycemic properties of different date cultivars and their derived products remain limited. This study aims to determine the glycemic index (GI) and glycemic load (GL) of commonly consumed Saudi date cultivars and their derived products in healthy subjects, and to evaluate their potential impact on postprandial glucose responses. The study will consist of 4 phases as follows: phase 1: Date varieties at Tamer stage; phase 2: date varieties at Rutab stage; phase 3: Date's debs; phase 4: Date's paste. For each phase, ten subjects will be asked to attend the laboratory in the morning after an overnight fast on several occasions. Each visit will be separated from the next by a "washout" day. The reference food, 50 g of glucose dissolve in 250 ml water will be tested on 3 alternating days to diminish day to day variation of glucose tolerance. 50g equivalent carbohydrates of dates will be consumed with 250 ml of water. Participants will be blinded to the type of the dates. Glucose will be measured in capillary blood samples following the two hours of the test meal consumption, at 15 min interval (0, 15, 30, 45, 60, 90 and 120 min) . A qualified technician will perform all blood glucose measurements.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- This is a randomized crossover interventional study, where each participant serves as his or her own control. All volunteers consume the reference glucose solution on three occasions and then consume each date product in separate sessions. After each test food, blood glucose is measured repeatedly over 120 minutes to determine the postprandial responses and subsequently calculate the glycemic index and glycemic load.
| Arm | Type | Receives |
|---|---|---|
| Single Group - Crossover Consumption of Date Products and Glucose Reference | Experimental | Other: Date Cultivars and Date-based ProductsAll participants will receive the glucose reference solution on three separate occasions and will consume the date or date-based product in individual sessions. Participants serve as their own control in a crossover design. Capillary blood glucose will be measured at several time points (0-120 minutes) after consumption to assess the glycemic index and load for each product. |
Who may qualify
- Ages
- 18 to 55 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Healthy adults aged 18 to 55 years
- Normotensive (normal blood pressure)
- Normal fasting glucose levels
- Not taking any prescription medication
- Able and willing to provide written informed consent
Key exclusion criteria (9 listed)
- Morbid obesity (BMI > 40 kg/m²)
- Pre-diabetic status
- Pregnancy
- Any gastrointestinal disorders
- History of gastroenteritis within the preceding six months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Date Cultivars and Date-based ProductsAlso: Tamer, Rutab, Date paste, Date molassesParticipants will consume 50 g of available carbohydrates from each date or date-based product, including 13 Tamer varieties, 12 Rutab varieties, 3 types of date paste, and 3 types of date molasses. Each product will be tested in a separate session.. The intervention will also include consumption of a glucose reference solution (50 g glucose) on three separate occasions. | Other | Single Group - Crossover Consumption of Date Products and Glucose Reference |
Primary outcome
Glycemic Index
Time frame: Baseline (fasting) and up to 120 minutes post-consumption on each test day.
The glycemic index of each date cultivar and date-based product will be determined on designated test days by calculating the incremental area under the blood glucose response curve (iAUC) over the 120-minute postprandial period following consumption of a portion containing 50 g of available carbohydrates, relative to the iAUC of a reference glucose solution. Blood glucose measurements will be obtained at baseline (fasting) and at predefined time points up to 120 minutes after ingestion.
1 secondary outcome
Glycemic Load (GL) of Fresh and Processed Date Products
Time frame: Baseline (fasting) and up to 120 minutes post-consumption on each test day.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Dec 2025.
- Background: PubMed 19079901Brouns F, Bjorck I, Frayn KN, Gibbs AL, Lang V, Slama G, Wolever TM. Glycaemic index methodology. Nutr Res Rev. 2005 Jun;18(1):145-71. doi: 10.1079/NRR2005100.
- Individual participant dataSharing planned: No. Notably, individual participant data will not be shared to ensure the privacy and confidentiality of the study participants. The data includes personal health information and making them publicly available might risk the identification of participants despite efforts to anonymize them.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Maha Alhussain, PhD study director
King Saud University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Date Cultivars and Date-based Products in people with Glycaemic Response Measurements, run by King Saud University at 1 site in Saudi Arabia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 31 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Saudi Arabia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Glycemic Index (time frame: Baseline (fasting) and up to 120 minutes post-consumption on each test day.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07286981, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Dec 2025; AzTrials last refreshed its copy on 7 Nov 2026.