Preoperative Clear Fluid FastingTimbarc-1NCT07288281
"Duration of Preoperative Clear Fluids Fasting in Patients Undergoing Liver Transplant"
An observational study of Preoperative Clear Fluid Fasting and Liver Transplant Recipient, run by Medical University of Warsaw at 1 site in Poland.
Trial summary
The goal of this prospective observational study is to report the duration of preoperative clear fluids fasting in patients undergoing liver transplant. It will also learn about the relationship between the duration of preoperative clear fluids fasting and changes in hemodynamic variables and metabolic profile at… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Preoperative Clear Fluid Fasting, Liver Transplant Recipient
- How many people
- 100 participants
- Where
- 1 sitePoland
- Study dates
- 1 Jun 2025to 1 Feb 2026
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients with liver diseases scheduled for elective liver transplant at University Clinical Centre of Medical University of Warsaw
Who may be able to join
- patients scheduled for elective liver transplant
Who cannot join
- patients unable to give detailed answer on clear fluid fasting due to severe hepatic encephalopathy or cognitive impairment
- lack of written informed consent
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Poland1 site, 1 recruiting
- Recruiting
University Clinical Centre of Medical University of Warsaw
Warsaw, Warszawa, 02-097
Paula Dudek, medical doctor, +48225992001, paula.dudek@wum.edu.pl
About this study
Official title: "Duration of Preoperative Clear Fluids Fasting in Patients Undergoing Liver Transplant. A Prospective Observational Study: the "Timbarc-1" a Pilot Study"
The goal of this prospective observational study is to report the duration of preoperative clear fluids fasting in patients undergoing liver transplant. It will also learn about the relationship between the duration of preoperative clear fluids fasting and changes in hemodynamic variables and metabolic profile at various anesthesia and transplant phases. The main questions it aims to answer are:
- How long liver recipient fast from clear fluids before liver transplant?
- Is there any relationship between the duration of preoperative clear fluids fasting and changes in blood pressure and hear rate after the induction of anesthesia?
- Is there any relationship between the duration of preoperative clear fluids fasting and blood glucose concentration, blood lactate concentration and acid base balance during anesthesia for liver transplant?
Read the detailed description
Clear fluids include water, certain juices without pulp (like apple or grape), clear sodas, tea or coffee without milk or cream, clear broth, sports drinks, gelatin, and popsicles without fruit pulp or yogurt.
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| liver recipient | liver transplant recipient undergoing liver transplantation in University Clinical Center of Medical University of Warsaw |
What is being measured
The primary outcome is the main question the study is designed to answer.
clear fluids fasting
duration of preoperative clear fluids fasting in patients undergoing liver transplant
Measured: before the induction of anesthesia
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Dec 2025
- Study start1 Jun 2025
- Primary completion31 Dec 2025 (estimated)
- Study completion1 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Preoperative Clear Fluid FastingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Medical University of Warsaw
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07288281
- Sponsor's protocol ID
- KB/67/2025
- Acronym
- Timbarc-1
- Status last verified
- Jun 2025
- First submitted
- 4 Dec 2025
- Last updated
- 7 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- "Duration of Preoperative Clear Fluids Fasting in Patients Undergoing Liver Transplant. A Prospective Observational Study: the "Timbarc-1" a Pilot Study"
- ClinicalTrials.gov ID
- NCT07288281
- Acronym / sponsor ID
- Timbarc-1 / KB/67/2025
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Medical University of WarsawUniversity, hospital or other
- Study start
- 1 Jun 2025 (actual)
- Primary completion
- 31 Dec 2025 (estimated)
- Study completion
- 1 Feb 2026 (estimated)
- First posted
- 17 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this prospective observational study is to report the duration of preoperative clear fluids fasting in patients undergoing liver transplant. It will also learn about the relationship between the duration of preoperative clear fluids fasting and changes in hemodynamic variables and metabolic profile at various anesthesia and transplant phases. The main questions it aims to answer are:
- How long liver recipient fast from clear fluids before liver transplant?
- Is there any relationship between the duration of preoperative clear fluids fasting and changes in blood pressure and hear rate after the induction of anesthesia?
- Is there any relationship between the duration of preoperative clear fluids fasting and blood glucose concentration, blood lactate concentration and acid base balance during anesthesia for liver transplant?
Detailed description
Clear fluids include water, certain juices without pulp (like apple or grape), clear sodas, tea or coffee without milk or cream, clear broth, sports drinks, gelatin, and popsicles without fruit pulp or yogurt.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 1 Day
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| liver recipient | – | –liver transplant recipient undergoing liver transplantation in University Clinical Center of Medical University of Warsaw |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with liver diseases scheduled for elective liver transplant at University Clinical Centre of Medical University of Warsaw
Key inclusion criteria (1 listed)
- patients scheduled for elective liver transplant
Key exclusion criteria (2 listed)
- patients unable to give detailed answer on clear fluid fasting due to severe hepatic encephalopathy or cognitive impairment
- lack of written informed consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
clear fluids fasting
Time frame: before the induction of anesthesia
duration of preoperative clear fluids fasting in patients undergoing liver transplant
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Jan 2026.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Preoperative Clear Fluid Fasting and Liver Transplant Recipient, run by Medical University of Warsaw at 1 site in Poland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 7 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Poland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Paula Dudek, Medical Doctor (+49225992001, paula.dudek@wum.edu.pl), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
clear fluids fasting (time frame: before the induction of anesthesia). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Jan 2026; AzTrials last refreshed its copy on 26 Oct 2026.