CancerSURGENCT07290309
Survivors Uniting for Remote Guided Exercise
A study testing Virtually Supervised Exercise Sessions and Asynchronous Group in people with Cancer and Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), run by Colorado State University at 1 site in United States.
Trial summary
The goal of this research study is to look at how live, online group exercise compares to recorded videos for helping increase physical activity levels, improve physical fitness and quality of life, and reduce loneliness among those living with and beyond cancer. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Cancer, Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Physical Activity
- What is being tested?
- Virtually Supervised Exercise Sessions and Asynchronous Group
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 300 participants
- Where
- 1 siteUnited States
- Study dates
- 6 Feb 2026to 1 Mar 2030
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Able to speak/read English,
- Diagnosed with any type of cancer within the last 5 years
- Completed primary or adjuvant treatment (i.e., chemotherapy, radiation therapy, surgery) with no planned treatment within the next nine months. This does not include long-term or chronic therapies such as anti-hormone or targeted therapies (e.g., aromatase inhibitor, androgen deprivation therapy, immunotherapies)
Who cannot join
- Existing participation in ≥150 minutes per week of at least moderate intensity aerobic exercise
- Known contraindications for non-medically supervised moderate or greater intensity exercise (e.g., uncontrolled hypertension, inability to walk without an assistive device)
- Current or planned participation in another structured program or intervention intended to encourage participation in exercise or physical activity.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Elena M Lancioni, MPH contact
United States1 site, 1 recruiting
- Recruiting
Human Performance Clinical Research Lab
Fort Collins, Colorado, 80523
Elena Lancioni, 970-491-4653, patplab@colostate.edu
About this study
Official title: Efficacy of a Group-based Videoconference Intervention to Increase Physical Activity in Cancer Survivors
The goal of this research study is to look at how live, online group exercise compares to recorded videos for helping increase physical activity levels, improve physical fitness and quality of life, and reduce loneliness among those living with and beyond cancer. The following aims have been established for this study:
- Aim 1: Examine the effect of a group-based videoconference physical activity (PA) intervention on moderate to vigorous physical activity [MVPA] (i.e., aerobic and resistance exercise).
- Aim 2: Examine the effect of the intervention on additional health-related outcomes including physical fitness (i.e., aerobic endurance, muscular strength), and quality of life at both timepoints.
- Aim 3: Explore potential mediators and moderators of intervention effects. We will examine mediators (e.g., self-efficacy, outcome expectations, group cohesion) and moderators (e.g., age, cancer stage, neighborhood walkability) of the intervention on MVPA.
- Exploratory Aim: Determine whether a group-based videoconference PA intervention reduces loneliness among cancer survivors.
Researchers will randomize participants into one of two guided exercise groups that are 12-weeks long in duration. Participants will be asked to complete online fitness assessments and surveys as well as wear a physical activity monitor device and watch a few times throughout the study. The whole study is 9-months long in duration with a 6-month free-living period where no study activities will take place.
Read the detailed description
For cancer survivors, moderate to vigorous intensity physical activity (MVPA) is associated with up to 50% reductions in cancer-specific and all-cause mortality. Previous studies also consistently demonstrate that MVPA improves cancer survivor's' physical function and quality of life. However, recent estimates suggest that only 14.2% of cancer survivors engage in the amount of MVPA considered necessary to achieve these health benefits, indicating a need for effective and wide-reaching interventions to increase MVPA.
Supervised interventions that utilize behavior change techniques like goal setting, social support, self-monitoring, action planning, and instruction on how to perform behavior, are most successful in increasing PA among cancer survivors. However, delivering these interventions face-to-face can be resource intensive, and present a barrier to cancer survivors in terms of access (e.g., no programs available nearby, and recently, due to social distancing requirements of the COVID-19 pandemic).
Web, text messaging, and other remote or distance-based PA interventions for cancer survivors demonstrate promise however they exhibit a smaller magnitude of effect on MVPA and physical and psychosocial outcomes than those that are delivered face-to-face. Key factors for this diminished effect size may be lower adherence/compliance due to lack of supervision, and fewer opportunities available for social interaction and support. Cancer survivors acknowledge the importance of peer support for PA, report that one of the quintessential facilitators for engaging in PA is the social benefit and describe camaraderie and the opportunity to be surrounded by others with a shared experience as motivating for being physically active.
The majority of remote or distance-based PA interventions for cancer survivors have been delivered asynchronously (i.e., occurs through online channels without real-time interaction), which eliminates direct supervision from a qualified exercise professional, and presents a challenge for tangible social connections. Conversely, virtually supervised PA interventions (i.e., using videoconferencing) are delivered synchronously, offering the opportunity for real-time supervision and social interaction, while retaining the scalability and reach advantages of remote delivery modalities. However, to date, there have been no large-scale, randomized controlled trials testing the efficacy of a group-based videoconference intervention to increase MVPA in cancer survivors. Videoconferencing can expand the reach of supervised, group-based interventions while potentially enhancing the effects of asynchronous distance-delivered modalities on MVPA, physical, and psychosocial outcomes. Thus, with the substantial, beneficial effects of PA for cancer survivors and the scalability potential of videoconference delivery, findings from this study stand to have high impact not only on the field of PA/exercise for cancer survivorship but can also inform similar interventions and programs for other chronic disease populations.
- Conditions
- Cancer, Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Physical Activity, Physical Activity Behavior, Cancer (With or Without Metastasis), Cancer - Chronic Lymphocytic Leukemia
- Being tested
- Virtually Supervised Exercise Sessions, Asynchronous Group
- Keywords
- Exercise oncology, Physical activity for cancer survivors, Group based exercise, Virtual exercise, physical activity, exercise, remote study, Cancer survivors
- Medical subject headings
- Neoplasms, Colonic Neoplasms, Breast Neoplasms, Lymphoma, Multiple Myeloma, Motor Activity, Ovarian Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Virtually Supervised Exercise SessionsBehavioural
Also called Live, Group-Based Zoom Class
The 12-week intervention will consist of supervised exercise sessions twice per week, and PA behavior change discussion sessions twice per month (bi-weekly) throughout the study for a total of five sessions (Week 2, 4, 6, 8 and 10). Exercise and PA behavior change discussion sessions will be informed by social cognitive theory, operationalize several BCT's, and include group dynamics-based strategies to enhance group cohesion. Exercise sessions will take place twice per week, lasting approximately one hour.
Asynchronous GroupBehavioural
Also called Pre-recorded exercise videos
The comparator will be an "unsupported intervention",128 which will use the same technology and provide the same content as the intervention but subtract the human components. Participants in the control group will receive access to pre-recorded (i.e., asynchronous) videos of the exercise and discussion sessions. The exercise videos will follow the same format as those in the intervention (i.e., instructor led, circuit-style aerobic and resistance exercises). Discussion sessions will operationalize the same BCT's using PowerPoint slides. Comparator arm participants will receive instructions on how to access these videos via a unique participant login to a secure website, Canvas, the same recommendations to achieve PA guidelines, and the same home-based exercise equipment (along with instructions for use).
| Study group | Role | What they receive |
|---|---|---|
| Intervention (Virtually Supervised Exercise Class) | Experimental | Live, group-based exercise classes will be delivered 2x per week on Zoom for 12-weeks along with a total of 5 behavior change discussion sessions. Receives: Behavioral: Virtually Supervised Exercise Sessions |
| Comparator (Asynchronous Exercise Sessions) | Active comparator | Participants will watch pre-recorded exercise and discussion videos for 12-weeks. Receives: Behavioral: Asynchronous Group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in accelerometer measured moderate to vigorous physical activity from baseline to 3- and 6-month follow-up
MVPA will be compared between the intervention and comparator arm from baseline to post-intervention (primary endpoint) and six-month follow-up.
Measured: Assessed at baseline, 3-and 6-month follow-up
Change in self-reported moderate-to-vigorous intensity physical activity from baseline to 3 and 6 month follow-up
Assessed by Godin Leisure Time Exercise Questionnaire (GLTEQ)
Measured: Assessed at baseline, 3 and 6-month follow-up
Secondary outcomes (2)
Quality of life will be assessed by a quantitative self-report questionnaire
A quality of life survey will be sent at three time points throughout the study: Enrollment, 3-month follow-up, \& 6-month follow-up. QOL is assessed on a scale of (1-5) and has different subscales wherein some subscales have a reverse scoring system.
Measured: Assessed at baseline and 3 and 6 month follow-up
Physical fitness assessed by sit-to-stand and 2-minute step test
Participants will complete a total of three study assessments at the following timepoints: Enrollment, 3 -month follow-up, \& 6-month follow-up from program completion
Measured: Assessed at baseline and 3 and 6 month follow-up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Dec 2025
- Study start6 Feb 2026
- Primary completion1 Dec 2029 (estimated)
- Study completion1 Mar 2030 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CancerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This study is a two-arm randomized controlled trial. Following the NIH Stage Model for Behavioral Intervention Development, we propose a stage II intervention, with the goal of traditional efficacy testing consisting of experimental testing in research settings, with research-based providers
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 300 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Colorado State University
- Sponsor type
- University, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Responsible party
- Principal investigator, Heather Leach, Colorado State University
- Investigators
- Heather J Leach, PhD, Principal investigator, Colorado State University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07290309
- Sponsor's protocol ID
- 6002
- Other IDs
- 1R01CA296965-01
- Acronym
- SURGE
- Status last verified
- Mar 2026
- First submitted
- 15 Dec 2025
- Last updated
- 31 Mar 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 31 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Efficacy of a Group-based Videoconference Intervention to Increase Physical Activity in Cancer Survivors
- ClinicalTrials.gov ID
- NCT07290309
- Acronym / sponsor ID
- SURGE / 6002
- Conditions
- Cancer, Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Physical Activity, Physical Activity Behavior, Cancer (With or Without Metastasis), Cancer - Chronic Lymphocytic Leukemia
- Keywords
- Exercise oncology, Physical activity for cancer survivors, Group based exercise, Virtual exercise, physical activity, exercise, remote study, Cancer survivors
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 300 participants (estimated)
- Lead sponsor
- Colorado State UniversityUniversity, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Study start
- 6 Feb 2026 (actual)
- Primary completion
- 1 Dec 2029 (estimated)
- Study completion
- 1 Mar 2030 (estimated)
- First posted
- 18 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this research study is to look at how live, online group exercise compares to recorded videos for helping increase physical activity levels, improve physical fitness and quality of life, and reduce loneliness among those living with and beyond cancer. The following aims have been established for this study:
- Aim 1: Examine the effect of a group-based videoconference physical activity (PA) intervention on moderate to vigorous physical activity [MVPA] (i.e., aerobic and resistance exercise).
- Aim 2: Examine the effect of the intervention on additional health-related outcomes including physical fitness (i.e., aerobic endurance, muscular strength), and quality of life at both timepoints.
- Aim 3: Explore potential mediators and moderators of intervention effects. We will examine mediators (e.g., self-efficacy, outcome expectations, group cohesion) and moderators (e.g., age, cancer stage, neighborhood walkability) of the intervention on MVPA.
- Exploratory Aim: Determine whether a group-based videoconference PA intervention reduces loneliness among cancer survivors.
Researchers will randomize participants into one of two guided exercise groups that are 12-weeks long in duration. Participants will be asked to complete online fitness assessments and surveys as well as wear a physical activity monitor device and watch a few times throughout the study. The whole study is 9-months long in duration with a 6-month free-living period where no study activities will take place.
Detailed description
For cancer survivors, moderate to vigorous intensity physical activity (MVPA) is associated with up to 50% reductions in cancer-specific and all-cause mortality. Previous studies also consistently demonstrate that MVPA improves cancer survivor's' physical function and quality of life. However, recent estimates suggest that only 14.2% of cancer survivors engage in the amount of MVPA considered necessary to achieve these health benefits, indicating a need for effective and wide-reaching interventions to increase MVPA.
Supervised interventions that utilize behavior change techniques like goal setting, social support, self-monitoring, action planning, and instruction on how to perform behavior, are most successful in increasing PA among cancer survivors. However, delivering these interventions face-to-face can be resource intensive, and present a barrier to cancer survivors in terms of access (e.g., no programs available nearby, and recently, due to social distancing requirements of the COVID-19 pandemic).
Web, text messaging, and other remote or distance-based PA interventions for cancer survivors demonstrate promise however they exhibit a smaller magnitude of effect on MVPA and physical and psychosocial outcomes than those that are delivered face-to-face. Key factors for this diminished effect size may be lower adherence/compliance due to lack of supervision, and fewer opportunities available for social interaction and support. Cancer survivors acknowledge the importance of peer support for PA, report that one of the quintessential facilitators for engaging in PA is the social benefit and describe camaraderie and the opportunity to be surrounded by others with a shared experience as motivating for being physically active.
The majority of remote or distance-based PA interventions for cancer survivors have been delivered asynchronously (i.e., occurs through online channels without real-time interaction), which eliminates direct supervision from a qualified exercise professional, and presents a challenge for tangible social connections. Conversely, virtually supervised PA interventions (i.e., using videoconferencing) are delivered synchronously, offering the opportunity for real-time supervision and social interaction, while retaining the scalability and reach advantages of remote delivery modalities. However, to date, there have been no large-scale, randomized controlled trials testing the efficacy of a group-based videoconference intervention to increase MVPA in cancer survivors. Videoconferencing can expand the reach of supervised, group-based interventions while potentially enhancing the effects of asynchronous distance-delivered modalities on MVPA, physical, and psychosocial outcomes. Thus, with the substantial, beneficial effects of PA for cancer survivors and the scalability potential of videoconference delivery, findings from this study stand to have high impact not only on the field of PA/exercise for cancer survivorship but can also inform similar interventions and programs for other chronic disease populations.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- This study is a two-arm randomized controlled trial. Following the NIH Stage Model for Behavioral Intervention Development, we propose a stage II intervention, with the goal of traditional efficacy testing consisting of experimental testing in research settings, with research-based providers
| Arm | Type | Receives |
|---|---|---|
| Intervention (Virtually Supervised Exercise Class) | Experimental | Behavioral: Virtually Supervised Exercise SessionsLive, group-based exercise classes will be delivered 2x per week on Zoom for 12-weeks along with a total of 5 behavior change discussion sessions. |
| Comparator (Asynchronous Exercise Sessions) | Active comparator | Behavioral: Asynchronous GroupParticipants will watch pre-recorded exercise and discussion videos for 12-weeks. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Able to speak/read English,
- Diagnosed with any type of cancer within the last 5 years
- Completed primary or adjuvant treatment (i.e., chemotherapy, radiation therapy, surgery) with no planned treatment within the next nine months. This does not include long-term or chronic therapies such as anti-hormone or targeted therapies (e.g., aromatase inhibitor, androgen deprivation therapy, immunotherapies)
Key exclusion criteria (3 listed)
- Existing participation in ≥150 minutes per week of at least moderate intensity aerobic exercise
- Known contraindications for non-medically supervised moderate or greater intensity exercise (e.g., uncontrolled hypertension, inability to walk without an assistive device)
- Current or planned participation in another structured program or intervention intended to encourage participation in exercise or physical activity.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Virtually Supervised Exercise SessionsAlso: Live, Group-Based Zoom ClassThe 12-week intervention will consist of supervised exercise sessions twice per week, and PA behavior change discussion sessions twice per month (bi-weekly) throughout the study for a total of five sessions (Week 2, 4, 6, 8 and 10). Exercise and PA behavior change discussion sessions will be informed by social cognitive theory, operationalize several BCT's, and include group dynamics-based strategies to enhance group cohesion. Exercise sessions will take place twice per week, lasting approximately one hour. | Behavioural | Intervention (Virtually Supervised Exercise Class) |
| Asynchronous GroupAlso: Pre-recorded exercise videosThe comparator will be an "unsupported intervention",128 which will use the same technology and provide the same content as the intervention but subtract the human components. Participants in the control group will receive access to pre-recorded (i.e., asynchronous) videos of the exercise and discussion sessions. The exercise videos will follow the same format as those in the intervention (i.e., instructor led, circuit-style aerobic and resistance exercises). Discussion sessions will operationalize the same BCT's using PowerPoint slides. Comparator arm participants will receive instructions on how to access these videos via a unique participant login to a secure website, Canvas, the same recommendations to achieve PA guidelines, and the same home-based exercise equipment (along with instructions for use). | Behavioural | Comparator (Asynchronous Exercise Sessions) |
Primary outcome
Change in accelerometer measured moderate to vigorous physical activity from baseline to 3- and 6-month follow-up
Time frame: Assessed at baseline, 3-and 6-month follow-up
MVPA will be compared between the intervention and comparator arm from baseline to post-intervention (primary endpoint) and six-month follow-up.
Change in self-reported moderate-to-vigorous intensity physical activity from baseline to 3 and 6 month follow-up
Time frame: Assessed at baseline, 3 and 6-month follow-up
Assessed by Godin Leisure Time Exercise Questionnaire (GLTEQ)
2 secondary outcomes
Quality of life will be assessed by a quantitative self-report questionnaire
Time frame: Assessed at baseline and 3 and 6 month follow-up
Physical fitness assessed by sit-to-stand and 2-minute step test
Time frame: Assessed at baseline and 3 and 6 month follow-up
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Mar 2026.
- Study website where participants can learn more about the study and register interestLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Elena M Lancioni, MPH contact
Heather J Leach, PhD principal investigator
Colorado State University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Virtually Supervised Exercise Sessions and Asynchronous Group in people with Cancer and Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), run by Colorado State University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 31 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Heather J Leach, PhD ((970) 491-8951, heather.leach@colostate.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in accelerometer measured moderate to vigorous physical activity from baseline to 3- and 6-month follow-up (time frame: Assessed at baseline, 3-and 6-month follow-up). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Mar 2026.