Healthy AdultsPhase 4RCTNCT07291336
Comparing Dynamic Navigation to Static Navigation in the Implant Placement
A Phase 4 study testing Dynamic navigation system and Static Implant guide in people with Healthy Adults and Dental Implant, run by Ain Shams University at 1 site in Egypt.
Trial summary
Implant placement is preplanned by taking xrays and impressions for the mouth one group a guide is fabricated and used to guide the implant drilling all through to the implant placement the other group, no guide is fabricated, but the implant is placed by dynamic navigation through looking in a screen and checking… Read more about this study
- Who is it for?
- Ages 22 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy Adults, Dental Implant, Accuracy
- What is being tested?
- Dynamic navigation system and Static Implant guide
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 20 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Oct 2022to Jan 2026
- Phase
- Phase 4
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 22 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy patients at least 22 years old.
- At least one missing tooth to be restored using an implant in the upper jaw from the maxillary right 2nd premolar to the maxillary left 2nd premolar.
- At least six residual teeth in the affected jaw (5).
- Minimum of 5 mm available bone.
Who cannot join
- Medical condition or medication that would impair bone healing.
- Poor oral hygiene
- Inadequate bone width or height that may need bone augmentation. 5
- Alcohol users.
- Smoking more than 10 cigarettes per day.
- History of head and neck radiotherapy.
Show all 9Show fewer
- Pregnant females.
- Uncontrolled hypertensive or diabetic patient.
- Vulnerable group; prisoners, pregnant women, orphans…etc
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Ain Shams University, Faculty of Dentistry
Cairo
Mohamed Wagdy Bissar, Associate Professor, 01006687399 ext. +2, Mohamedwagdy.1@gmail.com
Hala Kamal Abdel Gaber, Professor, 01222338526 ext. +2, Dr.halakamal@hotmail.com
About this study
Official title: Accuracy Assessment of Dynamic Vs. Static Navigation Implant Placement Protocols (Randomized Controlled Trial)
Implant placement is preplanned by taking xrays and impressions for the mouth one group a guide is fabricated and used to guide the implant drilling all through to the implant placement the other group, no guide is fabricated, but the implant is placed by dynamic navigation through looking in a screen and checking where the implant is fully placed
- Conditions
- Healthy Adults, Dental Implant, Accuracy
- Being tested
- Dynamic navigation system, Static Implant guide
- Keywords
- dynamic navigation, static navigation, guide, Accuracy, delayed implant
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dynamic navigation systemDevice
Also called dCAIS
Dynamic navigation system called MiniNavident
Static Implant guideDevice
Tooth supported guide is prefabricated before the surgery
| Study group | Role | What they receive |
|---|---|---|
| sCAIS | Active comparator | Not described Receives: Device: Static Implant guide |
| dCAIS | Experimental | Not described Receives: Device: Dynamic navigation system |
What is being measured
The primary outcome is the main question the study is designed to answer.
Deviation
Deviation in Apical position, platform position and angular deviation
Measured: Baseline, Day 0
Secondary outcomes (2)
Patient Satisfaction Questionnaire
Patient satisfaction from procedure
Measured: 1 week
Time
Operating time taken for each procedure
Measured: Perioperative/ Periprocedural
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Dec 2025
- Study start1 Oct 2022
- Primary completionJan 2026 (estimated)
- Study completionJan 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Healthy AdultsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase 4
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 20 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ain Shams University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Salma Nabil Ahmed Lotfy Mobarek, Ain Shams University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07291336
- Sponsor's protocol ID
- 1113
- Acronym
- RCT
- Status last verified
- Nov 2025
- First submitted
- 22 Nov 2025
- Last updated
- 18 Dec 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: All IPD will be shared
Study at a glance
From the registry record, last updated by the sponsor on 18 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Accuracy Assessment of Dynamic Vs. Static Navigation Implant Placement Protocols (Randomized Controlled Trial)
- ClinicalTrials.gov ID
- NCT07291336
- Acronym / sponsor ID
- RCT / 1113
- Conditions
- Healthy Adults, Dental Implant, Accuracy
- Keywords
- dynamic navigation, static navigation, guide, Accuracy, delayed implant
- Phase
- Phase 4
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 20 participants (estimated)
- Lead sponsor
- Ain Shams UniversityUniversity, hospital or other
- Study start
- 1 Oct 2022 (actual)
- Primary completion
- Jan 2026 (estimated)
- Study completion
- Jan 2026 (estimated)
- First posted
- 18 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Implant placement is preplanned by taking xrays and impressions for the mouth one group a guide is fabricated and used to guide the implant drilling all through to the implant placement the other group, no guide is fabricated, but the implant is placed by dynamic navigation through looking in a screen and checking where the implant is fully placed
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| sCAIS | Active comparator | Device: Static Implant guide |
| dCAIS | Experimental | Device: Dynamic navigation system |
Who may qualify
- Ages
- 22 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Healthy patients at least 22 years old.
Key exclusion criteria (9 listed)
- Medical condition or medication that would impair bone healing.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dynamic navigation systemAlso: dCAISDynamic navigation system called MiniNavident | Device | dCAIS |
| Static Implant guideTooth supported guide is prefabricated before the surgery | Device | sCAIS |
Primary outcome
Deviation
Time frame: Baseline, Day 0
Deviation in Apical position, platform position and angular deviation
2 secondary outcomes
Patient Satisfaction Questionnaire
Time frame: 1 week
Time
Time frame: Perioperative/ Periprocedural
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Dec 2025.
- Individual participant dataSharing planned: Yes. All IPD will be shared
Related trials for Healthy Adults
RecruitingPhase 1
A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008)
Healthy
Not yet recruitingPhase 1
A Study to Learn How Different Amounts of the Study Medicine Called PF-08161842 Are Tolerated and Act in the Body in Healthy and Older Adults
Alzheimer Disease
Not yet recruiting
Nutrition Intervention for Older Adults and Research Training
Impaired Mobility
Active, not recruitingPhase 1
Trial to Evaluate Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults Aged 50 To 64 Years
Pneumonia, Bacterial
Not yet recruiting
Comparison Between Eccentric Hamstring Training and Sprint-Specific Training
Healthy Adult, Athlete
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A Phase 4 study testing Dynamic navigation system and Static Implant guide in people with Healthy Adults and Dental Implant, run by Ain Shams University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 18 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
What does this phase mean?
Phase 4 studies take place after a treatment is approved, to learn more about its long-term benefits and risks in everyday use.
Not every study follows the same path, and some studies (observational studies, device studies) have no phase.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Deviation (time frame: Baseline, Day 0). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Dec 2025.