Evaluation of the Effect of Perioperative Recruitment Maneuver Practice on Lung Ultrasound Score and Mechanical Power in Pediatric Patients

Pulmonary atelectasis refers to incomplete expansion of the alveoli and terminal bronchioles. Atelectasis impairs oxygenation of the blood and reduces lung compliance. Pulmonary atelectasis is common in patients undergoing general anesthesia. The pediatric patientgroup is more sensitive to hypoxemia due to lower functional residual capacity and increased metabolic requirements compared to adults. Therefore, preventing and detecting atelectasis is important. Recruitment maneuvers open collapsed alveoli, increase gas exchange, and improve oxygenation. Lung ultrasound is a fast, simple, non-invasive, and radiation-free technique for diagnosing anesthesia-induced atelectasis. Mechanical work is a recently defined ventilation parameter. This concept represents the energy transferred by the ventilator to the respiratory system per unit time. Part of this energy may directly affect lung tissue, causing ventilator-induced lung injury. Mechanical work is calculated based on a combination of parameters such as tidal volume, respiratory rate, driver pressure, and peak pressure. Mechanical work is a comprehensive measure that reflects the static and dynamic components of these variables together. In intensive care patients, both driving pressure and mechanical power have been shown to be associated with morbidity and mortality. However, in the pediatric patient group, the effect of mechanical power during the intraoperative period on postoperative pulmonary complications has not been sufficiently investigated. Limiting intraoperative mechanical power may reduce the risk of postoperative complications.This study aimed to determine the effectiveness of the recruitment maneuver in preventing atelectasis using lung ultrasound during the intraoperative period, to examine the relationship between the lung ultrasound score and mechanical power, and to demonstrate the effect of the recruitment maneuver on postoperative pulmonary complications.

During the study period, patients aged 1-14 years who underwent surgery in the operating rooms of Cerrahpaşa Medical Faculty, with an ASA score of 1-3, and a surgical duration of at least 2 hours will be included in the study. Patients with an ASA score of 4 or defined lung disease (patients using medication due to asthma and having made 2 emergency visits within 1 year), prematurity (< 36 weeks gestation/bronchopulmonary dysplasia), cystic fibrosis, diagnosed syndromic disease, congenital cardiac disease, abnormal chest X-ray, chest wall deformity, or history of previous chest surgery will be excluded from the study. All patients will be ventilated in VG-Pressure guaranteed mode, Tidal volume will be calculated as ideal body weight x 6-8 ml/kg GROUP 1: Fixed PEEP: 5 cm H2O, GROUP 2: PEEP: 5 cm H2O, 5 cycles, recruitment maneuver will be performed with pre-extubation plateau P < 35 cm H2O and vital capacity x 2

. GROUP 3: PEEP: 5 cm H2O, 5 cycles of recruitment maneuvers will be performed in the right-left lateral decubitus position before extubation with plateauP < 35 cm H2O and vital capacity x 2.

This study will be performed pre-induction (1), 5 minutes after intubation (2), pre-extubation (3), and finally 5 minutes after extubation (4). In the lung ultrasonographic examinations performed, each hemithorax will be divided into 6 regions, and pleural shift, A-line, Air Bronchogram, B score, and Consolidation score will be evaluated at each of the two Plaps points in terms of B score and consolidation score.

Lung scores will be calculated and recorded. Starting from the pre-induction period, at 5 minutes post-intubation and every hour thereafter, KAH, OAB, SpO2, FiO2, ETCO2, Peak P, Plateau P, Delta P, Compliance, driving pressures, mechanical power calculations, and values will be recorded.

Additionally, in groups where the recruitment maneuver is performed, pre- and post-maneuver values will be recorded. Additionally, in groups undergoing recruitment maneuvers, pre- and post-maneuver values will be recorded.

Mechanical power; MPvcv = RR x TV x (PIP - [(Pplat - PEEP) x 0.5]) x 0.098 Dynamic power : (TV x RR x [(Pplato + tPEEP) x 0.5) x 0.098 Driving force: (TV x RR x [ (Pplato - tPEEP) x 0.5] x 0.098 Mechanical Energy (0.098 (TV kg) (PIP -[(Pplato - PEEP) x 0.5] All patients will be premedicated with midazolam (0.05 -1 mg/kg) if vascular access is available, then taken to the operating room. After patients are taken to the operating room, standard monitoring will be performed (SPO2, ECG, and non-invasive blood pressure measurement). Following preoxygenation with 100% O2, induction will be performed with thiopental 5 mg/kg, propofol 2 mg/kg, fentanyl 2 mcg/kg, rocuronium 0.6 mg/kg. After tracheal intubation, the mechanical ventilator will be set to pressure-controlled mode with tidal volume: 8 ml/kg, PEEP: 5 cmH2O, FIO2: 40%, respiratory rate ETCO2: 35-45. Anesthesia maintenance will be provided with sevoflurane/oxygen. 2 mg/kg sugammadex will be used when waking patients. The Aldrete scoring system will be used for service transfer in the recovery unit.

Patients will be monitored for desaturation, fever, and oxygen needs during the 24-hour postoperative period, and findings will be recorded.